Computational Methods in Synthetic Biology

Buch | Hardcover

358 Seiten

2014
Humana Press Inc. (Verlag)
978-1-4939-1877-5 (ISBN)

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This volume provides complete coverage of the computational approaches currently used in Synthetic Biology. Chapters focus on computational methods and algorithms for the design of bio-components, insight on CAD programs, analysis techniques, and distributed systems. Written in the highly successful Methods in Molecular Biology series format, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results in the laboratory.

Authoritative and practical, Computational Methods in Synthetic Biology serves as a guide to plan in silico the in vivo or in vitro construction of a variety of synthetic bio-circuits.

Computational Protein Design Methods for Synthetic Biology.- Computer-Aided Design Of DNA Origami Structures.- Computational Design Of RNA Parts, Devices, and Transcripts With Kinetic Folding Algorithms Implemented On Multiprocessor Clusters.- Regulatory RNA Design Through Evolutionary Computation And Strand Displacement.- Programming Languages for Circuit Design.- Kappa Rule-Based Modelling in Synthetic Biology.- Modular Design Of Synthetic Gene Circuits With Biological Parts and Pools.- Computationally Guided Design Of Robust Gene Circuits.- Chemical Master Equation Closure for Computer-Aided Synthetic Biology.- Feedback loops in biological networks.- Efficient Analysis Methods in Synthetic Biology.- Using Computational Modeling and Experimental Synthetic Perturbations to Probe Biological Circuits.- In Silico Control Of Biomolecular Processes.- Stochastic Modular Analysis For Gene Circuits: Interplay Among Retroactivity, Nonlinearity, and Stochasticity.- Distributed Model Construction with Virtual Parts.- The Synthetic Biology Open Language.- Computational Methods For The Construction, Editing, and Error Correction Of DNA Molecules And Their Libraries.

Reihe/Serie	Methods in Molecular Biology ; 1244
Zusatzinfo	43 Illustrations, color; 93 Illustrations, black and white; XI, 358 p. 136 illus., 43 illus. in color.
Verlagsort	Totowa, NJ
Sprache	englisch
Maße	178 x 254 mm
Themenwelt	Mathematik / Informatik ► Informatik ► Theorie / Studium
	Informatik ► Weitere Themen ► Bioinformatik
	Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie
Schlagworte	algorithms • bio-components • CAD programs • computational methods • Distributed Systems • DNA assembly protocols • DNA Parts • gene circuit in silico • RNA devices • synthetic network
ISBN-10	1-4939-1877-X / 149391877X
ISBN-13	978-1-4939-1877-5 / 9781493918775
Zustand	Neuware