Clinical Trials with Missing Data (eBook)

A Guide for Practitioners

Michael O'Kelly, Bohdana Ratitch (Autoren)

eBook Download: PDF | EPUB

2014 | 1. Auflage
472 Seiten
John Wiley & Sons (Verlag)
978-1-118-76253-0 (ISBN)

Infos

This book provides practical guidance for statisticians,
clinicians, and researchers involved in clinical trials in the
biopharmaceutical industry, medical and public health
organisations. Academics and students needing an introduction to
handling missing data will also find this book invaluable.

The authors describe how missing data can affect the outcome and
credibility of a clinical trial, show by examples how a clinical
team can work to prevent missing data, and present the reader with
approaches to address missing data effectively.

The book is illustrated throughout with realistic case studies and
worked examples, and presents clear and concise guidelines to
enable good planning for missing data. The authors show how to
handle missing data in a way that is transparent and easy to
understand for clinicians, regulators and patients. New
developments are presented to improve the choice and implementation
of primary and sensitivity analyses for missing data. Many SAS code
examples are included - the reader is given a toolbox for
implementing analyses under a variety of assumptions.

Autor

MICHAEL O'KELLY, Senior Strategic Biostatistics Director, Quintiles Ireland Ltd, Ireland. BOHDANA RATITCH, Senior Biostatistician, Quintiles, Montreal, Canada.

Rezensionen

"In summary, the book is a must-have tool for any biostatistician dealing with missing data. It is an excellent reference book for postgraduate students or researchers working in the area of missing data." (Biometrical Journal, 1 June 2015)

"This is an excellent addition to the field, dealing with problems arising from missing data or unobserved data in clinical trials. It successfully bridges the gap between clinicians and statisticians using relatively common language to build common ground." (Doody's, 9 January 2015)

Produkt-Details

• Erscheint lt. Verlag: 14.2.2014
• Reihe/Serie: Statistics in Practice
• Reihe/Serie: Statistics in Practice
• Sprache: englisch
• Themenwelt: Mathematik / Informatik ► Mathematik ► Statistik
• Themenwelt: Mathematik / Informatik ► Mathematik ► Wahrscheinlichkeit / Kombinatorik
• Themenwelt: Medizin / Pharmazie ► Medizinische Fachgebiete
• Themenwelt: Studium ► Querschnittsbereiche ► Epidemiologie / Med. Biometrie
• Schlagworte: Clinical Trials • Klinische Studien • Medical Science • Medical Statistics & Epidemiology • Medizin • Medizinische Statistik u. Epidemiologie • Pharmaceutical Statistics • Pharmazeutische Statistik • Statistics • Statistik
• ISBN-10: 1-118-76253-3 / 1118762533
• ISBN-13: 978-1-118-76253-0 / 9781118762530