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Systems Analysis of Human Multigene Disorders

Natalia Maltsev, Andrey Rzhetsky, T. Conrad Gilliam (Herausgeber)

Buch | Hardcover

122 Seiten

2013
Springer-Verlag New York Inc.
978-1-4614-8777-7 (ISBN)

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Understanding the genetic architecture underlying complex multigene disorders is one of the major goals of human genetics in the upcoming decades. Advances in whole genome sequencing and the success of high throughput functional genomics allow supplementing conventional reductionist biology with systems-level approaches to human heredity and health as systems of interacting genetic, epigenetic, and environmental factors. This integrative approach holds the promise of unveiling yet unexplored levels of molecular organization and biological complexity. It may also hold the key to deciphering the multigene patterns of disease inheritance.

Wellness and Health Omics Linked to the Environment: the WHOLE approach to personalized medicine.- Characterizing Multi-omic Data in Systems Biology.- High-throughput Translational Medicine: Challenges and Solutions.- Computational approaches for human disease gene prediction and ranking.- A Personalized Treatment for Lung Cancer: Molecular Pathways, Targeted Therapies, and Genomic Characterization.- Index.

Reihe/Serie	Advances in Experimental Medicine and Biology ; 799
Zusatzinfo	12 Illustrations, color; XIII, 122 p. 12 illus. in color. With online files/update.
Verlagsort	New York, NY
Sprache	englisch
Maße	155 x 235 mm
Themenwelt	Mathematik / Informatik ► Informatik ► Theorie / Studium
	Informatik ► Weitere Themen ► Bioinformatik
	Studium ► 2. Studienabschnitt (Klinik) ► Humangenetik
	Naturwissenschaften ► Biologie
ISBN-10	1-4614-8777-3 / 1461487773
ISBN-13	978-1-4614-8777-7 / 9781461487777
Zustand	Neuware