New Developments in Chromatin Research

Neil M Simpson, Valerie J Stewart (Herausgeber)

Buch | Hardcover

247 Seiten

2012
Nova Science Publishers Inc (Verlag)
978-1-62081-816-9 (ISBN)

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Chromatin is DNA plus the proteins (and RNA) that package DNA within the cell nucleus. The primary functions of chromatin are: to package DNA into a smaller volume to fit in the cell, to strengthen the DNA to allow mitosis and meiosis and prevent DNA damage, and to control gene expression and DNA replication. In this book, the authors present topical research in the study of chromatin including the varied functions of aurora kinases A and B in mitosis and carcinogenesis; the chromatin state of pluripotent stem cells; MITF meets chromatin in melanoma; the state of chromatin as an integrative indicator of cell stress; analysing DNA damage and its repair throughout entire genomes; the cloning process, structural characterisation of Revolver transposon and its patented application for chromosome tags; DNA damage and Rad16; and glucocorticoid-induced chromatin remodelling.

Preface; The Varied Functions of Aurora Kinases A & B in Mitosis & Carcinogenesis; New Developments in Chromatin Research: An Epigenetic Perspective; The Chromatin State of Pluripotent Stem Cells; MITF Meets Chromatin in Melanoma; The State of Chromatin as an Integrative Indicator of Cell Stress; A Genomics Approach to Analysing DNA Damage & its Repair throughout Entire Genomes; Recent Patent on Revolver-2: A Novel Transposon-Like Gene Useful for Chromosome Tags of Rye.

Zusatzinfo	Illustrations (some col.)
Verlagsort	New York
Sprache	englisch
Maße	260 x 180 mm
Gewicht	488 g
Themenwelt	Informatik ► Weitere Themen ► Bioinformatik
Themenwelt	Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie
ISBN-10	1-62081-816-7 / 1620818167
ISBN-13	978-1-62081-816-9 / 9781620818169
Zustand	Neuware