Control of Cell Fate in the Circulatory and Ventilatory Systems (eBook)
X, 538 Seiten
Springer New York (Verlag)
978-1-4614-0329-6 (ISBN)
The volumes in this authoritative series present a multidisciplinary approach to modeling and simulation of flows in the cardiovascular and ventilatory systems, especially multiscale modeling and coupled simulations. The cardiovascular and respiratory systems are tightly coupled, as their primary function is to supply oxygen to and remove carbon dioxide from the body's cells. Because physiological conduits have deformable and reactive walls, macroscopic flow behavior and prediction must be coupled to nano- and microscopic events in a corrector scheme of regulated mechanisms. Therefore, investigation of flows of blood and air in physiological conduits requires an understanding of the biology, chemistry, and physics of these systems together with the mathematical tools to describe their functioning.
Volumes 1 and 2 are devoted to cell organization and fate, as well as activities that are autoregulated and/or controlled by the cell environment. Volume 1 examined cellular features that allow adaptation to environmental conditions. Volume 2 begins with a survey of the cell types of the nervous and endocrine systems involved in the regulation of the vasculature and respiratory tract and growth factors. It then describes major cell events in the circulatory and ventilatory systems, such as cell growth, proliferation, migration, and death. Circadian cycles that drive rhythmic gene transcription are also covered.
The volumes in this authoritative series present a multidisciplinary approach to modeling and simulation of flows in the cardiovascular and ventilatory systems, especially multiscale modeling and coupled simulations. The cardiovascular and respiratory systems are tightly coupled, as their primary function is to supply oxygen to and remove carbon dioxide from the body's cells. Because physiological conduits have deformable and reactive walls, macroscopic flow behavior and prediction must be coupled to nano- and microscopic events in a corrector scheme of regulated mechanisms. Therefore, investigation of flows of blood and air in physiological conduits requires an understanding of the biology, chemistry, and physics of these systems together with the mathematical tools to describe their functioning. Volumes 1 and 2 are devoted to cell organization and fate, as well as activities that are autoregulated and/or controlled by the cell environment. Volume 1 examined cellular features that allow adaptation to environmental conditions. Volume 2 begins with a survey of the cell types of the nervous and endocrine systems involved in the regulation of the vasculature and respiratory tract and growth factors. It then describes major cell events in the circulatory and ventilatory systems, such as cell growth, proliferation, migration, and death. Circadian cycles that drive rhythmic gene transcription are also covered.
Introduction1. Remote Control2. Cell Growth and Proliferation3. Growth Factors4. Cell Survival and Death5. Circadian Clock6. Cell MotilityConcluding RemarksReferencesAppendix: Notations—Aliases and SymbolsNotations—Prefixes and SuffixesBiochemical, Medical, and Physical AliasesMathematical Symbols, Molecules, and Physical QuantitiesIndex
| Erscheint lt. Verlag | 1.11.2011 |
|---|---|
| Reihe/Serie | Biomathematical and Biomechanical Modeling of the Circulatory and Ventilatory Systems | Biomathematical and Biomechanical Modeling of the Circulatory and Ventilatory Systems |
| Zusatzinfo | X, 538 p. |
| Verlagsort | New York |
| Sprache | englisch |
| Themenwelt | Mathematik / Informatik ► Mathematik |
| Medizinische Fachgebiete ► Innere Medizin ► Kardiologie / Angiologie | |
| Studium ► 1. Studienabschnitt (Vorklinik) ► Physiologie | |
| Naturwissenschaften ► Biologie ► Zoologie | |
| Naturwissenschaften ► Physik / Astronomie ► Angewandte Physik | |
| Technik ► Bauwesen | |
| Schlagworte | blood flow prediction • cardiovascular systems modeling • cell cytoskeleton • cell environment • cell membrane • Cell signalling • cell types systems • cell types tract • macroscopic blood flow behavior • modeling respiratory function • modeling simulation of flows • physiological flows • systems biology • ventilatory systems modeling |
| ISBN-10 | 1-4614-0329-4 / 1461403294 |
| ISBN-13 | 978-1-4614-0329-6 / 9781461403296 |
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