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Bioinformatics for Immunomics -

Bioinformatics for Immunomics

Buch | Softcover
192 Seiten
2012
Springer-Verlag New York Inc.
978-1-4614-2485-7 (ISBN)
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This fourth volume of a series is dedicated to advances in immunomics. The focus is on systemic and integrative approaches in basic and clinical immunology, immunoinformatics, and immunologically relevant instrumentation and high-throughput screening methods.
Like many words, the term “immunomics” equates to different ideas contingent on context. For a brief span, immunomics meant the study of the Immunome, of which there were, in turn, several different definitions. A now largely defunct meaning rendered the Immunome as the set of antigenic peptides or immunogenic proteins within a single microorganism – be that virus, bacteria, fungus, or parasite – or microbial population, or antigenic or allergenic proteins and peptides derived from the environment as a whole, containing also proteins from eukaryotic sources. However, times have changed and the meaning of immunomics has also changed. Other newer definitions of the Immunome have come to focus on the plethora of immunological receptors and accessory molecules that comprise the host immune arsenal. Today, Immunomics or immunogenomics is now most often used as a synonym for high-throughput genome-based immunology. This is the study of aspects of the immune system using high-throughput techniques within a conc- tual landscape borne of both clinical and biophysical thinking.

Computational Vaccinology.- The Immuno Polymorphism Database.- The IMGT/HLA Database.- Ontology Development for the Immune Epitope Database.- TEPIDAS: A DAS Server for Integrating T-Cell Epitope Annotations.- Databases and Web-Based Tools for Innate Immunity.- Structural Immunoinformatics: Understanding MHC-Peptide-TR Binding.- Discovery of Conserved Epitopes Through Sequence Variability Analyses.- Tunable Detectors for Artificial Immune Systems: From Model to Algorithm.- Defining the Elusive Molecular Self.- A Bioinformatic Platform for a Bayesian, Multiphased, Multilevel Analysis in Immunogenomics.

Reihe/Serie Immunomics Reviews: ; 3
Zusatzinfo XVI, 192 p.
Verlagsort New York, NY
Sprache englisch
Maße 155 x 235 mm
Themenwelt Mathematik / Informatik Informatik Theorie / Studium
Informatik Weitere Themen Bioinformatik
Studium 2. Studienabschnitt (Klinik) Humangenetik
Studium Querschnittsbereiche Infektiologie / Immunologie
Studium Querschnittsbereiche Prävention / Gesundheitsförderung
Naturwissenschaften Biologie Genetik / Molekularbiologie
Naturwissenschaften Biologie Mikrobiologie / Immunologie
Schlagworte Bioinformatik • Immunologie
ISBN-10 1-4614-2485-2 / 1461424852
ISBN-13 978-1-4614-2485-7 / 9781461424857
Zustand Neuware
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