Metchnikoff and the Origins of Immunology
From Metaphor to Theory
Seiten
1991
Oxford University Press Inc (Verlag)
978-0-19-506447-6 (ISBN)
Oxford University Press Inc (Verlag)
978-0-19-506447-6 (ISBN)
A critical study of the work of Elie Metchnikoff, the founding father of modern immunology. It explores Metchnikoff's development as an embryologist, showing how it prepared him to propose his theory of host-pathogen interaction.
This fascinating intellectual history is the first critical study of the work of Elie Metchnikoff, the founding father of modern immunology. Metchnikoff authored and championed the theory that phagocytic cells actively defend the host body against pathogens and diseased cells.
In this scientific biography, Tauber and Chernyak explore Metchnikoff's development as an embryologist, showing how it prepared him to propose his theory of host-pathogen interaction. They discuss the profound impact of Darwin's theory of evolution on his progress, and the influence of 19th century debates on vitalism, teleology, and mechanism. As a case study of scientific discovery, this work offers lucid insight into the process of creative science and its dependence on cultural and philosophic sources.
This fascinating intellectual history is the first critical study of the work of Elie Metchnikoff, the founding father of modern immunology. Metchnikoff authored and championed the theory that phagocytic cells actively defend the host body against pathogens and diseased cells.
In this scientific biography, Tauber and Chernyak explore Metchnikoff's development as an embryologist, showing how it prepared him to propose his theory of host-pathogen interaction. They discuss the profound impact of Darwin's theory of evolution on his progress, and the influence of 19th century debates on vitalism, teleology, and mechanism. As a case study of scientific discovery, this work offers lucid insight into the process of creative science and its dependence on cultural and philosophic sources.
Foreword; Preface; Introduction; Metchnikoff's early embryology; Metchnikoff's embryological studies after 1872; The problem of evolution in Metchnikoff's works; Metchnikoff's emerging concept of inflammation; The phagocytosis theory and its reception; The phagocyte eclipsed; Epilogue: From metaphor to theory; Notes and references; Appendix A: Morphologists vs. Darwinians, the modern debate; Appendix B: Current views of phagocyte function.
| Erscheint lt. Verlag | 31.10.1991 |
|---|---|
| Reihe/Serie | Monographs on the History and Philosophy of Biology |
| Verlagsort | New York |
| Sprache | englisch |
| Maße | 237 x 155 mm |
| Gewicht | 581 g |
| Themenwelt | Literatur ► Biografien / Erfahrungsberichte |
| Studium ► Querschnittsbereiche ► Geschichte / Ethik der Medizin | |
| Studium ► Querschnittsbereiche ► Infektiologie / Immunologie | |
| Naturwissenschaften ► Biologie ► Biochemie | |
| ISBN-10 | 0-19-506447-X / 019506447X |
| ISBN-13 | 978-0-19-506447-6 / 9780195064476 |
| Zustand | Neuware |
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