Human Immunodeficiency Virus (eBook)

Biology, Immunology, and Therapy

Emilio Emini (Herausgeber)

eBook Download: EPUB

2021
546 Seiten
Princeton University Press (Verlag)
978-0-691-22883-9 (ISBN)

Infos

The past few years have witnessed an explosive increase in our collective knowledge of the biology of the human immunodeficiency virus (HIV). Researchers have acquired new understanding of the virus's biochemistry, molecular biology, pathogenesis, genetics, and immunobiology. Resulting therapeutic advances have significantly prolonged the lives of thousands. Yet, the need to develop better therapies is ever more acute and--given the virus's continued spread through the human population--the need for an effective vaccine is urgent. These goals can be accomplished only through the experienced synthesis of information from the many disciplines participating in HIV research and through the insights of new investigators. This volume is designed to lower the barriers imposed on investigators by the sheer volume of available information--information that often can be found only in far-flung and specialized journals. It provides, in a single resource, an in-depth overview of the diverse areas that constitute HIV research. The result is a broad introduction for students and researchers new to the field as well as an integrated overview for researchers specialized in particular areas of HIV investigation. The volume will also benefit those seeking technical understanding of the virus's biology, including physicians treating HIV-infected patients. Each chapter is a comprehensive presentation of one area of current AIDS research--including work on the virus life cycle, epidemiology, genetics, protease and reverse transcriptase inhibitors, receptor and co-receptor interactions, therapeutic targets, clinical treatment, immunobiology, and vaccines--written by a leading researcher in that area. The contributors are Jon P. Anderson, Jan Balzarini, Elana Cherry, Thomas J. Coates, Chris Collins, Jon H. Condra, Mark B. Feinberg, Richard B. Gaynor, Matthias Gotte, Daria J. Hazuda, Spyros Kalams, Nathaniel R. Landau, Gerald H. Learn, Norman L. Letvin, James I. Mullins, Willscott E. Naugler, David Nickle, Matthew Rain, Allen G. Rodrigo, Daniel Shriner, Shalom Spira, Mario Stevenson, Todd Summers, Catherine Ulich, Joseph P. Vacca, Mark A. Wainberg, Bruce D. Walker, and Yang Wang.

Produkt-Details

• Erscheint lt. Verlag: 13.4.2021
• Zusatzinfo: 100 line illus.
• Sprache: englisch
• Themenwelt: Geisteswissenschaften ► Psychologie ► Sozialpsychologie
• Themenwelt: Medizin / Pharmazie ► Allgemeines / Lexika
• Themenwelt: Medizin / Pharmazie ► Gesundheitsfachberufe
• Themenwelt: Medizin / Pharmazie ► Medizinische Fachgebiete ► Medizinethik
• Themenwelt: Studium ► Querschnittsbereiche ► Infektiologie / Immunologie
• Schlagworte: Activation • Active Site • Amino acid • Antibody • Antigen • Antiviral Drug • Apoptosis • assay • CCR5 • CD4 • CD8 • Cell Culture • cell membrane • Chemokine • Chemokine receptor • Chemotherapy • Cofactor (biochemistry) • C-terminus • CXCR4 • Cytokine • Cytoplasm • Cytotoxic T cell • dendritic cell • Disease • Disease progression • DNA Synthesis • DNA, Viral • drug resistance • drug therapy • efficacy • Enzyme • Epidemic • Epitope • Feline immunodeficiency virus • gene expression • Gene product • glycoprotein • gp41 • HIV • HIV/Aids • HIV vaccine • Immortalised cell line • Immunodeficiency • Infection • infectivity • Integrase • in vitro • In vivo • Lentivirus • lymphocyte • Lysis • macrophage • major histocompatibility complex • Management of HIV/AIDS • Messenger RNA • Molecule • Moloney murine leukemia virus • monoclonal antibody • Mutagenesis • Mutation • mutation rate • Nucleic acid • Nucleotide • Oligonucleotide • opportunistic infection • pathogen • pathogenesis • Peptide • Phenotype • phosphorylation • Point mutation • Pre-integration complex • Processing (Chinese materia medica) • Processivity • Protease • Protein • Provirus • Receptor (biochemistry) • Resistance mutation • Retrovirus • reverse transcriptase • Reverse-transcriptase inhibitor • Ribonuclease H • RNA polymerase II • RNA, Viral • Simian immunodeficiency Virus • Superinfection • T Cell • Vaccine • Vertically transmitted infection • Viral envelope • viral load • Viral protein • Viral Replication • Viremia • Virus • virus assembly • vpr • VPU • Zidovudine
• ISBN-10: 0-691-22883-3 / 0691228833
• ISBN-13: 978-0-691-22883-9 / 9780691228839