Mild Cognitive Impairment

Aging to Alzheimer's Disease

Buch | Hardcover

288 Seiten

2003
Oxford University Press Inc (Verlag)
978-0-19-512342-5 (ISBN)

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This book examines mild cognitive impairment (MCI), the transitional period between normal ageing and very early Alzheimer's disease (AD). It addresses the issues involved and includes chapters on clinical studies, neuropsychology, neuroimaging, neuropathology, biological markers, diagnostic approaches, and treatment.

What are the boundary zones between normal aging and Alzheimer's disease (AD)? Are many elderly people whom we regard as normal actually in the early stages of AD? Alzheimer's disease does not develop overnight; the early phases may last for years or even decades. Recently, clinical investigators have identified a transitional condition between normal aging and and very early Alzheimer's disease that they have called mild cognitive impairment, or MCI. This term typically refers to memory impairment beyond what one would expect in individuals of a given age whose other abilities to function in daily life are well preserved. Persons who meet the criteria for mild cognitive impairment have an increased risk of progressing to Alzheimer's disease in the near future. Though many questions about this condition and its underlying neuropathology remain open, full clinical trials are currently underway worldwide aimed at preventing the progression from MCI to Alzheimer's disease. This book addresses the spectrum of issues involved in mild cognitive impairment, and includes chapters on clinical studies, neuropsychology, neuroimaging, neuropathology, biological markers, diagnostic approaches, and treatment. It is intended for clinicians, researchers, and students interested in aging and cognition, among them neurologists, psychiatrists, geriatricians, clinical psychologists, and neuropsychologists.

1. Conceptual Overview ; 2. Clinical features ; 3. Neuropsychiatric symptoms ; 4. Normative neuropsychology in ageing and Mild Cognitive Impairment ; 5. Optimizing cognitive test norms for detection ; 6. Magnetic resonance imaging ; 7. Functional imaging ; 8. Spectrum of pathology ; 9. Neuropathological changes in normal aging, mild cognitive impairment and Alzheimer's disease ; 10. Biological markers ; 11. Clinical evaluation ; 12. Treatment of mild cognitive impairment and prospects for prevention of Alzheimer's disease

Erscheint lt. Verlag	27.2.2003
Zusatzinfo	numerous line drawings and 1 halftone
Verlagsort	New York
Sprache	englisch
Maße	239 x 160 mm
Gewicht	649 g
Themenwelt	Geisteswissenschaften ► Psychologie ► Biopsychologie / Neurowissenschaften
	Geisteswissenschaften ► Psychologie ► Klinische Psychologie
	Medizin / Pharmazie ► Medizinische Fachgebiete ► Geriatrie
	Medizin / Pharmazie ► Medizinische Fachgebiete ► Neurologie
ISBN-10	0-19-512342-5 / 0195123425
ISBN-13	978-0-19-512342-5 / 9780195123425
Zustand	Neuware