Our Genes, Our Choices
Academic Press Inc (Verlag)
978-0-12-396952-1 (ISBN)
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Our Genes, Our Choices: How Genotype and Gene Interactions Affect Behavior — First Prize winner of the 2013 BMA Medical Book Award for Basic and Clinical Sciences — explains how the complexity of human behavior, including concepts of free will, derives from a relatively small number of genes, which direct neurodevelopmental sequence. Are people free to make choices, or do genes determine behavior? Paradoxically, the answer to both questions is "yes," because of neurogenetic individuality, a new theory with profound implications.
Author David Goldman uses judicial, political, medical, and ethical examples to illustrate that this lifelong process is guided by individual genotype, molecular and physiologic principles, as well as by randomness and environmental exposures, a combination of factors that we choose and do not choose.
Written in an authoritative yet accessible style, the book includes practical descriptions of the function of DNA, discusses the scientific and historical bases of genethics, and introduces topics of epigenetics and the predictive power of behavioral genetics.
David Goldman received his B.S. from Yale University in 1974, graduating in only three years, and his M.D. degree from the University of Texas Medical Branch in 1978. He joined the intramural program of the National Institutes of Health in 1979, and is currently Clinical Director and Chief of the Laboratory of Neurogenetics of the National Institute on Alcohol Abuse and Alcoholism. Throughout his career, he has identified genetic factors responsible for inherited differences in behavior, his laboratory pioneering in functional genomics – how differences in DNA sequence translate into behavioral differences from molecule to intermediate brain processes to behavior. He is recipient of many awards for his research and is one of the most highly cited scientists in biological psychiatry. His laboratory is currently exploring the genetics of substance use disorders and related health problems.
Chapter 1: INTRODUCTIONChapter 2: The Jinn in the genomeChapter 3: 2B or not 2B?Chapter 4: Stephen Mobley and his X-chromosomeChapter 5: Dial Multifactorial for Murder: The intersection of genes and cultureChapter 6: Distorted capacity: The measure of the impaired willChapter 7: Distorted capacity: Neuropsychiatric diseases and the impaired willChapter 8: Inheritance of Behavior and Genes “For Behavior Gene WarsChapter 9: The scientific and historic bases of genethics: Who watches the geneticists and by what principles? Chapter 10: The world is double helical DNA, RNA and proteins, in a few easy piecesChapter 11: The stochastic brain: From DNA blueprint to behaviorChapter 12: Reintroducing genes and behavior Chapter 13: Warriors and WorriersChapter 14: How many genes does it take to make a behavior? Chapter 15: The genesis and genetics of sexual behaviorChapter 16: Gene x environment interaction Chapter 17: The epigenetic revolution: Finding the imprint of the environment on the genomeChapter 18: DNA on TrialChapter 19: Parents and children: Neurogenetic determinism and Neurogenetic individualityChapter 20: Summing up genetic predictors of behavior
GlossarySuggested readingsIndex
| Verlagsort | San Diego |
|---|---|
| Sprache | englisch |
| Maße | 152 x 229 mm |
| Gewicht | 480 g |
| Themenwelt | Geisteswissenschaften ► Psychologie ► Biopsychologie / Neurowissenschaften |
| Studium ► 1. Studienabschnitt (Vorklinik) ► Physiologie | |
| Studium ► 2. Studienabschnitt (Klinik) ► Humangenetik | |
| ISBN-10 | 0-12-396952-2 / 0123969522 |
| ISBN-13 | 978-0-12-396952-1 / 9780123969521 |
| Zustand | Neuware |
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