Cell Therapy
Springer Nature Switzerland AG (Verlag)
978-981--961260-4 (ISBN)
- Titel nicht im Sortiment
- Artikel merken
This book provides an overview of cell-based therapy for human diseases including the definition, history, and clinical applications of human stem cells and their use in regenerative medicine. It covers human pluripotent stem cells (human embryonic stem cells and human induced pluripotent stem cells), mesenchymal stem/stromal cells, and hematopoietic stem cells, bone marrow mononuclear cells. In terms of clinical applications, this book also provides an update on recent human trials using these cells to treat various diseases, including neurological disorders, pulmonary dysfunctions, metabolic/endocrine-related diseases, frailty, and cancer treatment. In addition, it discusses the authors' clinical trial experiences related to these conditions in a clinical setting to provide additional insight into regenerative medicine, especially cell-based therapy. The field of regenerative medicine has witnessed tremendous advancement in stem cell research and therapy in recent years, with thousands of preclinical studies supporting thousands of human clinical trials conducted worldwide. Emerging evidence in regenerative medicine and stem cell research suggests the treatments are safe, whereas their therapeutic potential, effectiveness, and mode of action require deeper investigation. It is important to introduce the science behind stem cell-based therapy to patients, clinicians, and researchers to further enhance understanding of responsible clinical conduct and so to educate and thus prevent the further emergence of unregulated, deceitful stem cell clinics solely operating for the sake of profit.
Liem Nguyen Thanh Prof. Liem Nguyen Thanh is an innovator in pediatric endoscopic surgery and stem cell transplantation. He is a pioneer in application of stem cell therapy for unmet diseases in children such as cerebral palsy, autism, bronchopulmonary dysplasia, biliary atresia...He was Director of Vietnam National Children Hospital from 2002 to 2012. Currently, Prof. Liem is Director of Vinmec Research Institute of Stem Cell and Gene Technology and President of Vietnam Association of regenerative medicine and cell therapy. He has published 127 studies in international reviewed journals. He is the co-author of Operative Pediatric Surgery, Ashcraft’s Pediatric Surgery, and Pediatric Laparoscopic and Thoracospoc Surgery. He has been invited to give lectures on pediatric surgery and stem cell applications in the US, Europe, and Asia. He has been honored with many prestige national awards. In 2018, he was awarded the Nikkei Asia Prize in the Science and Technology category and was categorized in the top 100 scientists in Asia by the Singapore journal in 2019. Nicholas Forsyth Nick joined Aberdeen University in 2023 as Vice Principal (Research). Included in this role are development and implementation of coherent research strategies at School and University levels. His personal research interests span fundamental stem and somatic cell biology through to applied tissue engineering and regenerative medicine. He has particular expertise in delineating the role of physiological oxygen on cell biology, tendon, and respiratory systems. Nick studied Molecular Biology at Glasgow University before undertaking a PhD Molecular Genetics (at the CRUK Beatson Institute). After his PhD studies he performed his first postdoctoral studies at the University of Texas Southwestern Medical Centre, Dallas, TX, USA. He then moved back to the UK and joined the Roslin Institute, Edinburgh completing his training. In 2006 Nick joined Keele University as a Lecturer in Stem Cell Biology before being awarded his Chair in 2015. In 2016, as Professor of Stem Cell Biology he was appointed as Director of the Research Institute for Science and Technology in Medicine. Nick was appointed as Dean of Research in the Faculty of Medicine in 2019 before moving to Aberdeen in 2023. Michael Heke Dr. Heke started his career in pharmaceutical research (Bayer). He works in stem cell research since 2001. In 2006 he instituted a seminal clinical trial for SC therapy in heart failure (University Medical School Düsseldorf). In 2010, he became head of Department of Knowledge Management (University of Cologne) and was Scientific Coordinator for large-scale EU-Projects. He co-founded the German Stem Cell Network (GSCN), appointed by the German Federal Ministry for Education and Research (BMBF). In 2013, he rejoined Rockefeller University to co-lead its Department of Stem Cell Biology. In 2016, he was appointed Deputy to the President of Stanford University, managing the Bing Presidential Laboratory (Biology Department). He serves as Senior Advisor at Vinmec Research Institute for Stem Cell & Gene Technology (Hanoi), since 2017. Currently, he is the Crowley Center for Regenerative Biotherapeutics’ CSO (Rochester) focusing on clinical translation of stem cell research in regenerative medicine and aesthetics.
Chapter 1. Cellular Architects of Healing: A History of Cell Therapy in Medicine .- Chapter 2. Embryonic Stem Cells: The Dawn of Regenerative Promise .- Chapter 3. Mesenchymal stem cells .- Chapter 4. Bone Marrow-derived Mononuclear Cells and Umbilical Cord Blood-Derived Mononuclear Cells .- Chapter 5. iPSC Technology Applying in Drug Discovery .- Chapter 6. Biology of Extracellular Vesicles from Mesenchymal Stem Cell .- Chapter 7. Cell Therapy for Cerebral Palsy .- Chapter 8. Cell Therapy for Autism Spectrum Disorders .- Chapter 9. Cell Therapy for Spinal Cord Injury.- Chapter 10. Cell Therapy for Spina Bifida.- Chapter 11. Cell Therapy for Traumatic Brain Injury.- Chapter 12. Cell Therapy for Cerebral Stroke .- Chapter 13. Cell Therapy for Liver Cirrhosis .- Chapter 14. Cell Therapy for Biliary Atresia.- Chapter 15. Cell Therapy for Diabetes Mellitus .- Chapter 16. Stem Cell Therapy for Myocardial Infarction, Non-ischemic Cardiomyopathies and Heart Failure .- Chapter 17. Cell therapy for Chronic Obstructive Pulmonary Disease .- Chapter 18. Stem cell therapy for Treatment of Bronchopulmonary Dysplasia .- Chapter 19. Cell Therapies for Cartilage Repair and Osteoarthritis .- Chapter 20. Cell Therapy for Ovarian Deficiency and Female Sexual Dysfunction .- Chapter 21. Cell Therapy for Testosterone Deficiency and Male Sexual Dysfunction .- Chapter 22. Stem Cell-based Therapy for Treatment of Frailty .- Chapter 23. Clinical Applications of Exosomes.- Chapter 24. iPSC Technology Applying in Cell Therapy.
| Erscheint lt. Verlag | 25.4.2025 |
|---|---|
| Zusatzinfo | Approx. 350 p. 70 illus. in color. |
| Verlagsort | Cham |
| Sprache | englisch |
| Maße | 155 x 235 mm |
| Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Biomedizin |
| Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie | |
| Technik ► Umwelttechnik / Biotechnologie | |
| Schlagworte | Anti-Aging • Clinical applications and human trials • Clinical translation • Degenerative Diseases • Metabolic/endocrine-related diseases • Neurological disorders • Organ regeneration • Pulmonary dysfunctions • Regeneration • Regenerative medicine • Stem Cells • Stem Cell Therapy • Tissue repair • Traumatic Injuries • Treatment of frailty • Treatment of incurable diseases |
| ISBN-10 | 981--961260-8 / 9819612608 |
| ISBN-13 | 978-981--961260-4 / 9789819612604 |
| Zustand | Neuware |
| Haben Sie eine Frage zum Produkt? |
aus dem Bereich
