Routes to Essential Medicines
Wiley-Blackwell (Verlag)
978-1-119-72286-1 (ISBN)
This comprehensive workbook helps readers become familiar with the structures and synthetic challenges associated with nearly 300 essential medicines and gain the skills needed for pharmaceutical development.
- Highlights nearly three hundred medicines on the latest World Health Organization (WHO) Model List of Essential Medicines and their manufacturing routes
- Features exercises that equip students with the skills necessary to solve similar real-world problems
- Includes a retrosynthetic analysis for each commodity chemical and supplies an extensive list of key journal and information sites and a library of reagents, solvents, and conditions for many common organic reactions
Peter J. Harrington, PhD, is the owner and primary consultant for Better Pharma Processes LLC, Boulder, Colorado, USA. Dr. Harrington is a pharmaceutical process design and development expert with more than twenty years' experience in timely process innovation for major pharmaceuticals. His publications include a book on pharmaceutical process chemistry for synthesis and several articles on organic and medicinal chemistry.
Introduction xix
A 1
Abacavir 1
Acetazolamide 3
Acetylcysteine 4
Acetylsalicylic Acid 4
Acyclovir 5
Albendazole 6
Allopurinol 7
Amidotriazoate 8
Amikacin 9
Amiloride 11
4-Aminosalicylic Acid 12
Amiodarone 13
Amitriptyline 15
Amlodipine 16
Amodiaquine 17
Amoxicillin 18
Ampicillin 20
Anastrozole 21
Artemether 23
Artesunate 24
Ascorbic Acid 26
Atazanavir 27
Atracurium Besylate 29
Atropine 32
Azathioprine 34
Azithromycin 35
Aztreonam 37
B 40
Beclomethasone Dipropionate 40
Bedaquiline 45
Bendamustine 47
Benznidazole 49
Benzoyl Peroxide 50
Benzyl Benzoate 51
Betamethasone 52
Bicalutamide 56
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viii Contents
Biperiden 57
Bisoprolol 58
Budesonide 59
Bupivacaine 62
C 63
Caffeine 63
Calcium Folinate/Folinic Acid 64
Capecitabine 65
Carbamazepine 67
Cefalexin 68
Cefazolin 69
Cefepime 71
Cefixime 73
Cefotaxime 75
Ceftaroline 77
Ceftazidime 81
Ceftriaxone 84
Chlorambucil 86
Chloramphenicol 87
Chlorhexidine 89
Chloroquine 90
Chloroxylenol 91
Chlorpromazine 92
Ciprofloxacin 93
Cisplatin, Carboplatin, Oxaliplatin 94
Clarithromycin 97
Clindamycin 99
Clofazimine 100
Clomifene 101
Clomipramine 102
Clopidogrel 103
Cloxacillin 105
Clotrimazole 106
Clozapine 107
Codeine 108
Colecalciferol 109
Cyclizine 112
Cyclophosphamide 113
Cycloserine 114
Cytarabine 114
D 116
Dacarbazine 116
Daclatasvir 117
Dapsone 119
Darunavir 120
Dasabuvir 122
Dasatinib 124
Delamanid 126
Desmopressin 129
Dexamethasone 131
Diazepam 136
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Contents ix
Diethylcarbamazine 137
Dihydroartemisinin 139
Diloxanide Furoate 140
Dimercaprol 141
Docetaxel 141
Docusate Sodium 145
Dolutegravir 145
Dopamine 147
Doxycycline 148
E 150
Efavirenz 150
Eflornithine 152
Emtricitabine 153
Enalapril 155
Entecavir 158
Ephedrine 160
Epinephrine 160
Ergocalciferol 162
Ergometrine 163
Estradiol Cypionate 164
Ethambutol 166
Ethinylestradiol 166
Ethionamide 167
Ethosuximide 169
Etonogestrel 169
Etoposide 173
F 175
Fentanyl 175
Fluconazole 176
Flucytosine 177
Fludarabine Phosphate 177
Fludrocortisone Acetate 179
Fluorouracil 180
Fluoxetine 181
Fluphenazine 182
Folic Acid 184
Fomepizole 185
Formoterol 186
Fosfomycin 189
Furosemide 191
G 192
Gemcitabine 192
Gliclazide 194
Glutaral 195
Glyceryl Trinitrate 196
H 197
Haloperidol 197
Halothane 199
Hydralazine 199
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x Contents
Hydrochlorothiazide 200
Hydrocortisone 200
Hydroxycarbamide 203
Hydroxychloroquine 204
Hyoscine Butylbromide 205
I 207
Ibuprofen 207
Ifosfamide 208
Imatinib 209
Iohexol 210
Ipratropium Bromide 212
Irinotecan 214
Isoflurane 217
Isoniazid 218
Isosorbide Dinitrate 219
Itraconazole 219
Ivermectin 223
K 226
Ketamine 226
L 227
Lactulose 227
Lamivudine 228
Lamotrigine 229
Latanoprost 230
Ledipasvir 235
Leuprorelin 239
Levamisole 241
Levofloxacin 242
Levonorgestrel 244
Levothyroxine 247
Lidocaine 248
Linezolid 249
Loperamide 251
Lopinavir 252
Loratidine 255
Lorazepam 257
Losartan Potassium 259
Lumefantrine 261
M 263
Mannitol 263
Mebendazole 264
Medroxyprogesterone Acetate 265
Mefloquine 269
Meglumine Iotroxate 270
Melarsoprol 271
Mercaptopurine 272
Meropenem 274
Mesna 278
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Contents xi
Metformin 279
Methadone 279
Methotrexate 280
Methyldopa 282
Methylprednisolone 283
Methylthioninium Chloride 288
Metoclopramide 289
Metronidazole 290
Miconazole 291
Midazolam 292
Mifepristone 295
Miltefosine 298
Misoprostol 299
Moxifloxacin 302
N 305
Naloxone 305
Neostigmine Methylsulfate 306
Nevirapine 307
Niclosamide 309
Nicotinamide 309
Nifedipine 310
Nifurtimox 310
Nilotinib 311
Nitrofurantoin 313
Norethisterone and Norethisterone Enanate 314
O 317
Ofloxacin 317
Ombitasvir 319
Omeprazole 320
Ondansetron 322
Oseltamivir 323
Oxamniquine 325
Oxytocin 327
P 330
Paclitaxel 330
Paracetamol 333
Paritaprevir 334
Penicillamine 339
Pentamidine 340
Permethrin 341
Phenobarbital 342
Phenytoin 343
Piperacillin 344
Piperaquine 346
Praziquantel 347
Prednisolone 349
Primaquine 350
Procarbazine 352
Progesterone 353
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xii Contents
Proguanil 356
Propofol 356
Propranolol 357
Propylthiouracil 358
Prostaglandin E1 359
Prostaglandin E2 362
Pyrantel 366
Pyrazinamide 367
Pyridoxine 367
Pyridostigmine Bromide 369
Pyrimethamine 369
Pyronaridine 370
R 373
Raltegravir 373
Ranitidine 376
Retinoic Acid (All-trans) 377
Retinol (Vitamin A1) 378
Ribavirin 380
Rifabutin 382
Rifampicin 384
Rifapentine 386
Risperidone 389
Ritonavir 390
S 395
Salbutamol 395
Simeprevir 397
Simvastatin 402
Sodium Calcium Edetate 404
Sofosbuvir 405
Spironolactone 408
Succimer 410
Sulfadiazine and Silver Sulfadiazine 411
Sulfadoxine 412
Sulfamethoxazole 413
Sulfasalazine 415
Suramin 416
Suxamethonium Chloride 418
T 419
Tamoxifen 419
Tazobactam 421
Tenofovir Disoproxil 423
Terbinafine 424
Testosterone 425
Tetracaine 427
Tetracycline 428
Thiamine 428
Tigecycline 430
Timolol 434
Tranexamic Acid 435
Triclabendazole 436
Trimethoprim 437
Tropicamide 438
U 440
Ulipristal Acetate 440
V 445
Valganciclovir 445
Valproic Acid 447
Vecuronium Bromide 448
Velpatasvir 452
Verapamil 459
Vincristine 460
Vinorelbine 461
Voriconazole 463
W 466
Warfarin 466
X 467
Xylometazoline 467
Z 469
Zidovudine 469
Zoledronic Acid 471
A Demonstration: Amiodarone 472
Appendix A 478
Appendix B 594
Appendix C 595
Index 000
| Erscheinungsdatum | 09.12.2021 |
|---|---|
| Verlagsort | Hoboken |
| Sprache | englisch |
| Maße | 217 x 280 mm |
| Gewicht | 1374 g |
| Einbandart | kartoniert |
| Themenwelt | Medizin / Pharmazie ► Pharmazie |
| Naturwissenschaften ► Chemie ► Organische Chemie | |
| Technik ► Umwelttechnik / Biotechnologie | |
| ISBN-10 | 1-119-72286-1 / 1119722861 |
| ISBN-13 | 978-1-119-72286-1 / 9781119722861 |
| Zustand | Neuware |
| Haben Sie eine Frage zum Produkt? |
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