Prebiotic Chemistry and Chemical Evolution of Nucleic Acids (eBook)

César Menor-Salván (Herausgeber)

eBook Download: PDF

2018 | 1st ed. 2018
XVI, 291 Seiten
Springer International Publishing (Verlag)
978-3-319-93584-3 (ISBN)

Infos

The origin of life is one of the biggest unsolved scientific questions. This book deals with the formation and first steps of the chemical evolution of nucleic acids, including the chemical roots behind the origin of their components from the simplest sources in a geochemical context. Chemical evolution encompasses the chemical processes and interactions conducive to self-assembly and supramolecular organization, leading to an increase of complexity and the emergence of life. 

The book starts with a personal account of the pioneering work of Stanley Miller and Jeffrey Bada on the Chemistry of Origins of Life and how the development of organic chemistry beginning in the 19th century led to the emergence of the field of prebiotic chemistry, situated at the frontier between organic, geo- and biochemistry. It then continues reviewing in tutorial manner current central topics regarding the organization of nucleic acids: the origin of nucleobases and nucleosides, their phosphorylation and polymerization and ultimately, their self-assembly and supramolecular organization at the inception of life.

Dr. Menor-Salvan is astrobiologist and Professor of Biochemistry at Universidad de Alcala (Spain), and scientist affiliated to the Center for Chemical Evolution (Georgia Institute of Technology, USA). His main research interest is the Prebiotic Chemistry and Chemical Evolution of biopolymers and Origins of Life. 

Inhalt

Introduction: Reminiscing about Stanley Miller and Prebiotic ChemistryJeff Bada  ([e-mail])1. From the dawn of Organic Chemistry to Astrobiology: an historical perspective on the Prebiotic Chemistry of nucleobasesCesar  Menor-Salvan ([e-mail])2. Decomposition and condensation of nucleotides in hydrothermal fields.Bruce Damer and David Deamer ([e-mail])3. Nucleobases on the primitive Earth:  their sources and stabilityJim Cleaves and Jeff Bada ([e-mail])4. The Case for Mineralogy in the Origins of LifeHyo Joong Kim and Steven Benner ([e-mail])5. Urea: a common reagent behind the origin of bases, nucleosides and nucleotides.Cesar Menor-Salvan6. -title pending-David Fialho and Nick Hud ([e-mail]). Georgia Institute of Technology.7. The origin of the ionized linker: Geochemical predestination for phosphate?Matthew Pasek ([e-mail]) University of South Florida8. Prebiotic phosphorylationBradley Burcar ([e-mail]) Georgia Institute of Technology9. The Chemical Space of Nucleic AcidsJames H Cleaves ([e-mail])10. RNA and Protein: The Molecular Symbiosis at the Core of LifeAnton Petrov, Jessica C Bowman and Loren D. Williams ([e-mail]). Georgia Institute of Technology11. On the origin of interactions between nucleic acids and peptidesIrene Chen ([e-mail]) and Celia Blanco de Torres.  University of California-Santa Barbara.12. Self-Replication and Information Transfer of Nucleic-Acids Mediated by Non-Aqueous Environments.Isaac Gallego ([e-mail] ) and Christine He

Produkt-Details

• Erscheint lt. Verlag: 1.8.2018
• Reihe/Serie: Nucleic Acids and Molecular Biology
• Reihe/Serie: Nucleic Acids and Molecular Biology
• Zusatzinfo: XVI, 291 p. 113 illus., 58 illus. in color.
• Verlagsort: Cham
• Sprache: englisch
• Themenwelt: Naturwissenschaften ► Biologie
• Themenwelt: Naturwissenschaften ► Chemie ► Organische Chemie
• Themenwelt: Technik ► Maschinenbau
• Schlagworte: chemistry of purines and pyrimidines • Evolution • nucleotide synthesis • Origina of life • phosphorylation • RNA-world
• ISBN-10: 3-319-93584-4 / 3319935844
• ISBN-13: 978-3-319-93584-3 / 9783319935843