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Particle-Lung Interactions

Peter Gehr, Joachim Heyder (Herausgeber)

Buch | Hardcover
823 Seiten
2000
Marcel Dekker Inc (Verlag)
978-0-8247-9891-8 (ISBN)
CHF 279,95 inkl. MwSt
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Presents the developments in aerosol science and interactions between particles and the respiratory tract. This book covers therapeutic and diagnostic aspects of particle inhalation; surveys particles ranging in size from 0.0 1-10 microns interacting with pulmonary cells; and more. It is for pulmonologists, physiologists, allergists, and others.
This wide-ranging, comprehensive reference presents the latest developments in aerosol science and interactions between particles and the respiratory tract-utilizing an inter-disciplinary approach that integrates advances in physics, chemistry, and engineering with the epidemiological and biomedical sciences, and focusing on the dynamics of particle deposition, retention, and clearance.
Containing the work of more than 40 internationally recognized experts, Particle-Lung Interactions
covers therapeutic and diagnostic aspects of particle inhalation

surveys particles ranging in size from 0.01-10 microns interacting with pulmonary cells

analyzes stereological estimation of particle retention

reveals the sentinel of the pulmonary surveillance system

highlights the correlation between particulate air pollution and cardiovascular mortality

describes airborne irritants that activate neural reflexes

investigates particulate matter in clearance kinetics and inflammatory responses in the lungs

explores particle-surfactant interaction, keying on fine ambient particles at air-liquid interfaces

and more!
Abundantly referenced with over 2700 bibliographic citations, Particle-Lung Interactions is an indispensable resource for pulmonologists, physiologists, clinical immunologists, allergists, toxicologists, pediatricians and general practitioners, pharmacists, biochemists, surface physicists, and upper-level undergraduate, graduate, and medical school students in these disciplines.

Overview

Particle Interactions with the Respiratory Tract
Roger O. McClellan

Particles Interacting With The Lung

Environmental Particles
Alfred Wiedensohler, Frank Stratmann, and Ina Tegen
Particles Inhaled in the Occupational Setting
Joe L. Mauderly, Yung Sung Cheng, Neil F. Johnson, Mark D. Hoover, and Hsu-Chi Yeh
Medicinal Particles
Magnus Svartengren and Katharina Svartengren

Inhalation of Particles

Particle Deposition in the Respiratory Tract
Holger Schulz, Peter Brand, and Joachim Heyder
Structural and Interfacial Aspects of Particle Retention
Marianne Geiser, Vinzenz Im Hof, Samuel Schürch, and Peter Gehr
Clearance of Particles Deposited in the Lungs
Wolfgang G. Kreyling and Gerhard Scheuch

Molecular and Cellular Responses of the Lung to Inhaled Particles

Alterations in Gene Expression in Pulmonary Cells Following Particle Interactions
Jacob N. Finkelstein and Edward G. Barrett
Particle Uptake by Epithelial Cells
Andrew Churg
Responses of Inflammatory Cells
Robert B. Devlin, Andrew J. Ghio, and Daniel L. Costa
Dendritic Cells as Sentinels of Immune Surveillance in the Airways
Andrew S. McWilliam, Patrick G. Holt, and Peter Gehr
Potential Consequences of Interactions Between Aeroallergens and Cells Within the Respiratory Tree
Geoffrey A. Stewart, Andrew S. McWilliam, Cecile M. King, Philip J. Thompson, and Clive Robinson

Systemic Responses of the Lung to Inhaled Particles

Effect of Particles on Mucus and Mucociliary Clearance
Malcolm King
The Role of Surfactant in Disease Associated with Particle Exposure
Francis H. Y. Green, Peter Gehr, Martin M. Lee, and Samuel Schürch
Pathophysiological Mechanisms of Cardiopulmonary Effects
John J. Godleski and Robert W. Clarke
Neurally Mediated Cardiopulmonary and Systemic Responses to Inhaled Irrritants and Antigens
Donovan B. Yeates

Health Consequences

Interaction of Inhaled Particles with the Immune System
M. Ian Gilmour and Hillel S. Koren
Cardiopulmonary Consequences of Particle Inhalation
Mark W. Frampton, Jonathan M. Samet, and Mark J. Utell
Effects of Particulate Air Pollution Exposures
Douglas W. Dockery, C. Arden Pope III, and Frank E. Speizer

Reihe/Serie Lung Biology in Health and Disease
Verlagsort New York
Sprache englisch
Maße 216 x 279 mm
Gewicht 1179 g
Themenwelt Medizinische Fachgebiete Innere Medizin Pneumologie
Naturwissenschaften Biologie Humanbiologie
Technik Umwelttechnik / Biotechnologie
ISBN-10 0-8247-9891-0 / 0824798910
ISBN-13 978-0-8247-9891-8 / 9780824798918
Zustand Neuware
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