Characterization of Impurities and Degradants Using Mass Spectrometry (eBook)

Birendra Pramanik, Mike S. Lee (Herausgeber)

Guodong Chen (Autor)

eBook Download: PDF | EPUB

2011 | 1. Auflage
496 Seiten
John Wiley & Sons (Verlag)
978-0-470-92136-4 (ISBN)

Infos

The book highlights the current practices and future trends in
structural characterization of impurities and degradants. It begins
with an overview of mass spectrometry techniques as related to the
analysis of impurities and degradants, followed by studies
involving characterization of process related impurities (including
potential genotoxic impurities), and excipient related impurities
in formulated products. Both general practitioners in
pharmaceutical research and specialists in analytical chemistry
field will benefit from this book that will detail step-by-step
approaches and new strategies to solve challenging problems related
to pharmaceutical research.

Autor

BIRENDRA N. PRAMANIK is a Distinguished Fellow at Merck Research Laboratories, where he directs spectroscopy programs covering mass spectrometry and NMR efforts. He was previously a distinguished fellow at Schering-Plough Research Institute. He received his PhD in organic chemistry under the late Professor Ajay K. Bose from Stevens Institute of Technology in 1977. MIKE S. LEE is President of Milestone Development Services, a provider of consulting services specializing in pharmaceutical analysis and accelerated drug discovery and development strategies in Newtown, Pennsylvania. He previously directed program research at Bristol-Myers Squibb, Pharmaceutical Research Institute in New Brunswick, New Jersey. GUODONG CHEN is Principal Scientist in Bioanalytical and Discovery Analytical Sciences at Bristol-Myers Squibb in Princeton, New Jersey. He heads a mass spectrometry group in support of drug discovery as well as development programs in small molecule pharmaceuticals and biologics. He received his PhD in analytical chemistry from Purdue University under the direction of Professor R. Graham Cooks.

Rezensionen

"It will be valuable for scientists working in industrial,
academic, and healthcare-related fields who use mass spectrometry
to investigate impurities and degradants." (Doody's, 16 September
2011)

Produkt-Details

• Erscheint lt. Verlag: 4.8.2011
• Reihe/Serie: Wiley Series on Pharmaceutical Science
• Reihe/Serie: Wiley Series on Pharmaceutical Science
• Sprache: englisch
• Themenwelt: Naturwissenschaften ► Chemie ► Analytische Chemie
• Themenwelt: Technik
• Schlagworte: Analytical Chemistry • Analytische Chemie • Chemie • Chemistry • Drug Discovery & Development • Klein- und Mittelbetrieb • Massenspektrometrie • Mass Spectrometry • Wirkstoffforschung u. -entwicklung
• ISBN-10: 0-470-92136-6 / 0470921366
• ISBN-13: 978-0-470-92136-4 / 9780470921364