Mathematics of DNA Structure, Function and Interactions
Springer-Verlag New York Inc.
978-1-4614-2452-9 (ISBN)
Because of its outstanding record of interdisciplinary research and training, the IMA was an ideal venue for the 2007-2008 IMA thematic year on Mathematics of Molecular and Cellular Biology. The kickoff event for this thematic year was a tutorial on Mathematics of Nucleic Acids, followed by the workshop Mathematics of Molecular and Cellular Biology, held September 15--21 at the IMA. This volume is dedicated to the memory of Nicholas R. Cozzarelli, a dynamic leader who fostered research and training at the interface between mathematics and molecular biology. It contains a personal remembrance of Nick Cozzarelli, plus 15 papers contributed by workshop speakers. The papers give an overview of state-of-the-art mathematical approaches to the understanding of DNA structure and function, and the interaction of DNA with proteins that mediate vital life processes.
Nick Cozzarelli: A Personal Remembrance.- Mathematical Methods in Dna Topology: Applications to Chromosome Organization and Site-Specific Recombination.- Conformational Statistics of Dna and Diffusion Equations on The Euclidean Group.- Perspectives On DNA Looping.- Differences Between Positively and Negatively Supercoiled DNA that Topoisomerases May Distinguish.- Calibration of Tethered Particle Motion Experiments.- Difference Topology: Analysis of High-Order DNA-Protin Assemblies.- Useful Intrusions of DNA Topology Into Experiments on Protein-DNA Geometry.- Topological Analysis of DNA-Protein Complexes.- Closing the Loop on Protein-DNA Interactions: Interplay Between Shape and Flexibility in Nucleoprotein Assemblies Having Implications for Biological Regulation.- Four-Way Helical Junctions in DNA Molecules.- Micromechanics of Single Supercoiled DNA Molecules.- Flexibility Of Nucleosomes On Topologically Constrained DNA.- The Mathematics of DNA Sturcture, Mechanics, and Dynamics.- Paradox Regained: a Topological Coupling of Nuclesomal DNA Wrapping and Chromatin Fibre Coiling.- Statistical-Mechanical Analysis of Enzymatic Topological Transformations in DNA Molecules.
| Reihe/Serie | The IMA Volumes in Mathematics and its Applications ; 150 |
|---|---|
| Zusatzinfo | 70 Illustrations, color; XII, 356 p. 70 illus. in color. |
| Verlagsort | New York, NY |
| Sprache | englisch |
| Maße | 155 x 235 mm |
| Themenwelt | Informatik ► Weitere Themen ► Bioinformatik |
| Mathematik / Informatik ► Mathematik ► Algebra | |
| Mathematik / Informatik ► Mathematik ► Angewandte Mathematik | |
| Medizin / Pharmazie | |
| Naturwissenschaften ► Biologie | |
| Technik ► Medizintechnik | |
| ISBN-10 | 1-4614-2452-6 / 1461424526 |
| ISBN-13 | 978-1-4614-2452-9 / 9781461424529 |
| Zustand | Neuware |
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