Handbook of Industrial Cell Culture

Mammalian, Microbial, and Plant Cells

Victor A. Vinci, Sarad R. Parekh (Herausgeber)

Buch | Softcover

536 Seiten

2010 | Softcover reprint of hardcover 1st ed. 2003
Humana Press Inc. (Verlag)
978-1-61737-315-2 (ISBN)

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A diverse team of researchers, technologists, and engineers describe, in simple and practical language, the major current and evolving technologies for improving the biocatalytic capabilities of mammalian, microbial, and plant cells. The authors present state-of-the-art techniques, proven methods, and strategies for industrial screening, cultivation, and scale-up of these cells, and describe their biotech and industrial uses. Special emphasis is given to the solving critical issues encountered during the discovery of new drugs, process development, and the manufacture of new and existing compounds. Other topics include recombinant protein expression, bioinformatics, high throughput screening, analytical tools in biotechnology, DNA shuffling, and genomics discovery.

I. Mammalian Cell Culture.- 1 Analysis and Manipulation of Recombinant Glycoproteins Manufactured in Mammalian Cell Culture.- 2 • Genetic Approaches to Recombinant Protein Production in Mammalian Cells.- 3 • Protein Expression Using Transgenic Animals.- 4 • Mammalian Cell Culture: Process Development Considerations.- II. Microbial Cell Culture.- 5 • Natural Products: Discovery and Screening.- 6 • Genetic Engineering Solutions for Natural Products in Actinomycetes.- 7 • Culture Medium Optimization and Scale-Up for Microbial Fermentations.- III. Plant Cell Culture.- 8 • Functional Genomics for Plant Trait Discovery.- 9 • Molecular Tools for Engineering Plant Cells.- 10 • Plant Cell Culture: A Critical Tool for Agricultural Biotechnology.- 11 • Expression of Recombinant Proteins via the Plastid Genome.- 12 • Oleosin Partitioning Technology for Production of Recombinant Proteins in Oil Seeds.- IV. Critical Tools for Biotechnology.- 13 • Genome Sequencing and Genomic Technologies in Drug Discovery and Development.- 14 • Proteomics.- 15 • Metabolic Flux Analysis, Modeling, and Engineering Solutions.- 16 • Advances in Analytical Chemistry for Biotechnology: Mass Spectrometry of Peptides, Proteins, and Glycoproteins.- 17 • DNA Shuffling for Whole Cell Engineering.- 18 • Cell Culture Preservation and Storage for Industrial Bioprocesses.

"This book provides an updated, informative and practical knowledge of mammalian, microbial and plant cell culture methods for industrial use. The handbook can prove useful for students and experienced biotechnology professionals who are interested in industrial cell culture. The book is a great starting point and will be a useful addition to university libraries." -E-STREAMS

Erscheint lt. Verlag	5.11.2010
Zusatzinfo	1 Illustrations, color; 162 Illustrations, black and white; X, 536 p. 163 illus., 1 illus. in color.
Verlagsort	Totowa, NJ
Sprache	englisch
Maße	178 x 254 mm
Themenwelt	Schulbuch / Wörterbuch
	Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie
	Naturwissenschaften ► Biologie ► Zellbiologie
	Sozialwissenschaften
	Technik ► Umwelttechnik / Biotechnologie
ISBN-10	1-61737-315-X / 161737315X
ISBN-13	978-1-61737-315-2 / 9781617373152
Zustand	Neuware