Challenges of Biological Aging

Edward J. Masoro (Autor)

Buch | Softcover

220 Seiten

2000
Springer Publishing Co Inc (Verlag)
978-0-8261-0082-5 (ISBN)

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This volume provides the non-biologist an overview of what is known about the physiological bases of aging. The author examines the many basic theories and emerging hypotheses underlying the molecular, cellular, and systemic processes involved in senescence. He addresses the normal physiological changes that characterize the aging phenotype, and also considers the role of many age-associated diseases in growing older. Masoro synthesizes a much-needed "unified theory" of biological aging to which explains how and why the body grows into the condition we call "old." This text is intended for gerontology students in training, as well as for human physiologists interested in gerontology,.

Edward J. Masoro, PhD, was the chairman of the UTHSCSA Physiology Department for many years. Currently a professor emeritus, has has served as President of the Gerontological Society of America.

Preface

Acknowledgments

Aging: A Biological Puzzle

The Puzzle

Mortality Risk

Anatomical and Physiological Changes

Age-Associated Diseases

Concept of Biological Age

Genetics

Universality

Demography and the Societal Challenge

Population Mortality Data

Factors Determining Population Age Structure

Societal Impact of Changing Age Structure

Need for Biomedical Breakthroughs

Why Aging Occurs

Evolutionary Biology

History of Evolutionary Theories of Aging

Current Evolutionary Theory of Aging

Genetic Mechanisms in the Evolution of Aging

Evidence Supporting the Evolutionary Theory

How Aging Occurs

Overview

Theories, Hypotheses, and Concepts

Conclusions

Biological Basis of Aging: A Unifying Concept

Evolutionary Theory as a Guide

The Disposable Soma Theory of Aging

"Private" and "Public" Proximate Mechanisms of Aging

Unifying Concept

The Human Aging Phenotype

Body Structure and Composition

Skin

Musculoskeletal System

Nervous System

Cardiovascular System

Respiratory System

Renal and Urinary System

Gastrointestinal System

Endocrine and Metabolic Function

Female Reproductive System

Male Reproductive System

Immune System

Thermoregulation

Possible Interventions to Retard Aging

Dietary Restriction in Rodents

Proposed Pharmacological Interventions

Lifestyle and Environmental Factors

Index

Erscheint lt. Verlag	5.9.2000
Verlagsort	New York
Sprache	englisch
Gewicht	633 g
Themenwelt	Sachbuch/Ratgeber ► Gesundheit / Leben / Psychologie ► Lebenshilfe / Lebensführung
	Medizin / Pharmazie ► Medizinische Fachgebiete ► Geriatrie
	Naturwissenschaften ► Biologie
	Sozialwissenschaften ► Soziologie
ISBN-10	0-8261-0082-1 / 0826100821
ISBN-13	978-0-8261-0082-5 / 9780826100825
Zustand	Neuware