Annual Reports in Medicinal Chemistry (eBook)

eBook Download: PDF

1988 | 1. Auflage
389 Seiten
Elsevier Science (Verlag)
978-0-08-058367-9 (ISBN)

Infos

ANNUAL REPORTS IN MED CHEMISTRY V23 PPR

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Annual Reports in Medicinal Chemistry

Inhalt

Front Cover 1
Annual Reports in Medicinal Chemistry, Volume 23 4
Copyright Page 5
CONTENTS 6
CONTRIBUTORS 12
PREFACE 14
SECTION I: CNS AGENTS 16
Chapter 1. Antipsychotic Agents 16
Chapter 2. Analgesics 26
Chapter 3. Antianxiety Agents and Anticonvulsants 34
Chapter 4. Agents for the Treatment of Cognitive Disorders 44
Chapter 5. Central Nervous System Actions of Adenosine Agonists and Antagonists 54
Chapter 6. Central Serotonin Receptors: Opportunities for Drug Discovery 64
SECTION II: CARDIOPULMONARY AND VASCULAR AGENTS 74
Chapter 7. Antihypertensive Agents 74
Chapter 8. Pulmonary and Antiallergy Agents 84
Chapter 9. Peripheral Actions of Selective Muscarinic Agonists and Antagonists 96
Chapter 10. Vasopressin Antagonists 106
Chapter 11. Atrial Natriuretic Peptide 116
Chapter 12. Plasminogen Activators 126
SECTION III: CHEMOTHERAPEUTIC AGENTS 136
Chapter 13. Beta-Lactam Antibiotics 136
Chapter 14. Quinolone Antibacterial Agents 148
Chapter 15. Novel Approaches Toward Discovery of Antibacterial Agents 156
Chapter 16. Chemical Modification of Antibodies for Cancer Chemotherapy 166
Chapter 17. Antiviral Agents 176
SECTION IV: ENDOCRINOLOGY, IMMUNOLOGY AND METABOLIC DISORDERS 186
Chapter 18. Immunomodulatory Approaches to the Treatment of Inflammation 186
Chapter 19. Modulation of Arachidonic Acid Metabolism in the Treatment of Rheumatoid Arthritis 196
Chapter 20. The Pharmacological Treatment of Obesity 206
Chapter 21. Gastrointestinal Motility Enhancing Agents 216
Chapter 22. Luteinizing Hormone Releasing Hormone Analogs In Control of Fertility and Gonadal Hormone Dependent Disease 226
SECTION V: TOPICS IN BIOLOGY 236
Chapter 23. Structure and Function of G-Protein Coupled Receptors 236
Chapter 24. G-proteins as Receptor-Effector Couplers 250
Chapter 25. Isozymes of Protein Kinase C 258
Chapter 26. Therapeutic Strategies in the Treatment of AIDS 268
Chapter 27. Enzyme Changes Linked to Anticancer Drug Resistance 280
SECTION VI: TOPICS IN CHEMISTRY AND DRUG DESIGN 290
Chapter 28. Applications of NMR Spectroscopy to Protein Structure Determination 290
Chapter 29. Search Strategies for Determining Bioactive Conformers of Peptides and Small Molecules 300
Chapter 30. Oligonucleotide Inhibitors of Gene Expression in Living Cells: New Opportunities in Drug Design 310
Chapter 31. Enzyme Assisted Transformations in Organic Media 320
Chapter 32. Mechanistic Aspects of Xenobiotic Metabolism as Related to Drug Design 330
SECTION VII: SPECIAL TOPICS 340
Chapter 33. To Market, To Market – 1987 340
COMPOUND NAME, CODE NUMBER AND SUBJECT INDEX 364
CUMULATIVE CHAPTER TITLES KEYWORD INDEX, VOLUMES 1–23 374
CUMULATIVE CONTRIBUTOR INDEX, VOLUMES 1–23 382
CUMULATIVE NCE INTRODUCTION INDEX, 1983–1987 394
CUMULATIVE NCE INTRODUCTION INDEX, 1983–1987, BY INDICATION 400

Produkt-Details

• Erscheint lt. Verlag: 1.11.1988
• Mitarbeit: Herausgeber (Serie): Richard C. Allen
• Sprache: englisch
• Themenwelt: Sachbuch/Ratgeber
• Themenwelt: Medizin / Pharmazie ► Gesundheitsfachberufe
• Themenwelt: Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie
• ISBN-10: 0-08-058367-9 / 0080583679
• ISBN-13: 978-0-08-058367-9 / 9780080583679