Nicht aus der Schweiz? Besuchen Sie lehmanns.de

Selenium

Its Molecular Biology and Role in Human Health
Buch | Hardcover
444 Seiten
2006 | 2nd Revised edition
Springer-Verlag New York Inc.
978-0-387-33826-2 (ISBN)

Lese- und Medienproben

Selenium -
CHF 237,95 inkl. MwSt
zur Neuauflage
  • Titel erscheint in neuer Auflage
  • Artikel merken
Zu diesem Artikel existiert eine Nachauflage
Examines the molecular biology of selenium and how this element makes its way into protein. This title explores the role of this element in preventing certain forms of cancer, heart disease and other cardiovascular and muscle disorders.
This book examines the molecular biology of selenium and how this element makes its way into protein. The role of this element in preventing certain forms of cancer, heart disease and other cardiovascular and muscle disorders is explored in the text. The Second Edition outlines discoveries since this book was first introduced in 2001. Chapter updates have been written by investigators who have made important contributions to the field.

Contributors.- Foreword.- Preface.- Acknowledgements.- Selenium: A historical perspective.- Part I Biosynthesis of selenocysteine and its incorporation into protein: Selenium metabolism in prokaryotes.- Mammalian and other eukaryotic selenocysteine tRNAs.- Evolution of selenocysteine decoding and the key role of seleno-phosphate synthetase in the pathway of selenium utilization.- SECIS RNAs and K-turn binding proteins. A survey of evolutionary conserved RNA and protein motifs.- SECIS binding proteins and eukaryotic selenoprotein synthesis.- The importance of subcellular localization of SBP2 and EFsec for selenoprotein synthesis.- Selenocysteine biosynthesis and incorporation may require supramolecular complexes.- Part II Selenium-containing proteins: Deletion of selenoprotein P gene in the mouse.- Selenium and methionine sulfoxide reduction.- Selenoprotein W in development and oxidative stress.- The 15-kDa selenoprotein (Sep15): functional analysis and role in cancer.- Regulation of glutathione peroxidase-1 expression.- Selenoproteins of the glutathione system.- New roles of glutathione peroxidase-1 in oxidative stress and diabetes.- Selenoproteins of the thioredoxin system.- Mitochrondrial and cytosolic thioredoxin reductase knockout mice.- Selenium, deiodinases and endocrine function.- Biotechnology of selenium.- Part III Selenium and human health: Selenium, selenoproteins and brain function.- Selenium as a cancer preventive agent.- Peering down the kaleidoscope of thiol proteomics and unfolded protein response in studying the anticancer action of selenium.- Genetic variation among selenoprotein genes and cancer.- Selenium and viral infections.- Role of selenium in HIV/AIDS.- Effects of selenium on immunity and aging.- Selenium and male reproduction.- Mouse models for assessing the role of selenium in health and development.- Drosophila as a tool for studying selenium metabolism and role of selenoproteins.- Selenium in parasites.- Incorporating 'omics' approaches to elucidate the role of selenium and selenoproteins in cancer prevention.- Selenium-induced apoptosis.- Selenoprotein mimics.- Update of human dietary standards for selenium.- Index.

Erscheint lt. Verlag 7.11.2006
Zusatzinfo 72 black & white illustrations, 17 black & white tables
Verlagsort New York, NY
Sprache englisch
Maße 155 x 235 mm
Gewicht 801 g
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Onkologie
Studium Querschnittsbereiche Infektiologie / Immunologie
Naturwissenschaften Biologie Biochemie
ISBN-10 0-387-33826-8 / 0387338268
ISBN-13 978-0-387-33826-2 / 9780387338262
Zustand Neuware
Haben Sie eine Frage zum Produkt?
Mehr entdecken
aus dem Bereich

von Oliver Schmetzer

Buch | Softcover (2023)
Urban & Fischer in Elsevier (Verlag)
CHF 37,80