Transgenic and Knockout Models of Neuropsychiatric Disorders

Gene S. Fisch, Jonathan Flint (Herausgeber)

Buch | Hardcover

296 Seiten

2006
Humana Press Inc. (Verlag)
978-1-58829-507-1 (ISBN)

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In this up-to-date survey and critical assessment of transgenic and knockout models in neuropsychiatry and behavior, a panel of leading researchers comprehensively assesses how and whether the genetic abnormalities produced from these models manifest the neuropsychiatric disorders to which they correspond. The authors focus on transgenic and knockout models of neurocognitive dysfunction and neuropsychiatric dysfunction. The discussion of neurobiological problems covers mental retardation, polyglutamate, and speech disorders, as well as disorders that involve cognitive, social, speech, and language dysfunction. The neuropsychiatric dysfunctions examined include psychosis and schizophrenia, anxiety, depression, and bipolar disorder.

and Overview.- Transgenic and Knockout Models of Psychiatric Disorders.- Transgenic Mouse Models and Human Psychiatric Disease.- Transgenic and Knockout Mouse Models.- If Only They Could Talk.- Transgenic and Knockout Models of Neurocognitive Dysfunction.- Spinocerebellar Ataxia Type 1.- Mouse Models of Hereditary Mental Retardation.- How Can Studies of Animals Help to Uncover the Roles of Genes Implicated in Human Speech and Language Disorders?.- Animal Models of Autism.- Transgenic and Knockout Models of Neuropsychiatric Dysfunction.- Genetic Mouse Models of Psychiatric Disorders.- Animal Models of Psychosis.- Animal Models of Anxiety.- Modeling Human Anxiety and Depression in Mutant Mice.- Mutant Mouse Models of Bipolar Disorder.

Reihe/Serie	Contemporary Clinical Neuroscience
Zusatzinfo	20 Illustrations, black and white; XII, 296 p. 20 illus.
Verlagsort	Totowa, NJ
Sprache	englisch
Maße	155 x 235 mm
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Neurologie
	Medizin / Pharmazie ► Studium
	Naturwissenschaften ► Biologie ► Humanbiologie
ISBN-10	1-58829-507-9 / 1588295079
ISBN-13	978-1-58829-507-1 / 9781588295071
Zustand	Neuware