Essential Developmental Biology

Jonathan M. W. Slack (Autor)

Buch | Softcover

376 Seiten

2005 | 2nd Revised edition
Blackwell Publishing Ltd (Verlag)
978-1-4051-2216-0 (ISBN)

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TO ACCESS THE DEDICATED TEXTBOOK WEBSITE, PLEASE VISIT www.blackwellpublishing.com/slack Essential Developmental Biology, 2nd Edition, is a concise and well-illustrated treatment of this subject for undergraduates. With an emphasis throughout on the evidence underpinning the main conclusions, this book is suitable as the key text for both introductory and more advanced courses in developmental biology. * Includes new chapters on Evolution & Development, Gut Development, & Growth and Aging. * Contains expanded treatment of mammalian fertilization, the heart and stem cells. * Now features a glossary, notated further reading, and key discovery boxes. * Illustrated with over 250 detailed, full-color drawings. * Accompanied by a dedicated website, featuring animated developmental processes, a photo gallery of selected model organisms, and all art in PowerPoint and jpeg formats (also available to instructors on CD-ROM). An Instructor manual CD-ROM for this title is available. Please contact our Higher Education team at HigherEducation@wiley.com for more information.

Professor Jonathan Slack has worked in London and Oxford and is currently Head of the Department of Biology and Biochemistry at the University of Bath in England. He is a member of the European Molecular Biology Organization and a Fellow of the Academy of Medical Sciences. He is a leading authority in developmental biology and has published over 150 scientific papers, as well as the well-received monograph From Egg to Embryo and the lighthearted and popular Egg and Ego.

Preface. Section 1: Groundwork. 1 The excitement of developmental biology. Where the subject came from. Central position in biology. Impact on society. Future impact. 2 Common features of development. Genomic equivalence, cloning of animals. Gametogenesis. Early development. Morphogenetic processes. Growth and death. 3 Developmental genetics. Developmental mutants. Screening for mutants. Cloning of genes. Transgenesis. Gene duplication. 4 Experimental embryology. Normal development. Developmental commitment. Acquisition of commitment. Homeotic genes. Criteria for proof. 5 Techniques for the study of development. Microscopy. Study of gene expression by biochemical methods. Study of gene expression by in situ methods. Reporter genes. Microinjection. Cell-labeling methods. Cell sorting. Section 2: Major model organisms. 6 Model organisms. The big six. Availability and cost. Access and micromanipulation. Genetics and genome maps. Relevance and tempo. 7 Xenopus. Oogenesis, maturation, fertilization. Embryonic development. Experimental methods. Regional specification. Inductive interactions. 8 The zebrafish. Normal development. Mutagenesis. Regional specification. 9 The chick. Normal development. Regional specification of the early embryo. Description of organogenesis in the chick. 10 The mouse. Mammalian fertilization. Normal embryonic development. Technology of mouse development. Regional specification in development. Other topics in mouse development. 11 Drosophila. Insects. Normal development. Drosophila developmental genetics. Overview of the developmental program. The dorsoventral pattern. The anteroposterior system. 12 Caenorhabditis elegans. Normal development. Regional specification in the embryo. Analysis of postembryonic development. Programmed cell death. Section 3: Organogenesis. 13 Tissue organization and stem cells. Types of tissue. Tissue renewal. Skin. Intestine. Hematopoietic system. 14 Development of the nervous system. Overall structure and cell types. Anteroposterior patterning of the neural plate. Dorsoventral patterning of the neural tube. Neurogenesis and gliogenesis. The neural crest. Development of neuronal connectivity. 15 Development of mesodermal organs. Somitogenesis and myogenesis. The kidney. Germ cell and gonadal development. Limb development. Heart and blood vessels. 16 Development of endodermal organs. Normal development. Determination of the endoderm. The pancreas. 17 Drosophila imaginal discs. Metamorphosis. Genetic study of larval development. Mitotic recombination. Disc development. Regional patterning of the wing disc. Section 4: Growth, regeneration, and evolution. 18 Growth, aging, and cancer. Size and proportion. Growth in stature. Aging. Postnatal disorders of growth and differentiation. 19 Regeneration of missing parts. Distribution of regenerative capacity. Planarian regeneration. Vertebrate limb regeneration. 20 Evolution and development. Macroevolution. The primordial animal. What really happened in evolution? Appendix: Key molecular components. Genes. Transcription factor families. Signaling systems. Inducing factor families. Cytoskeleton. Cell adhesion molecules. Extracellular matrix components. Glossary. Index.

Erscheint lt. Verlag	16.9.2005
Zusatzinfo	797 illustrations
Verlagsort	Oxford
Sprache	englisch
Maße	218 x 276 mm
Gewicht	1180 g
Themenwelt	Naturwissenschaften ► Biologie ► Allgemeines / Lexika
Themenwelt	Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie
ISBN-10	1-4051-2216-1 / 1405122161
ISBN-13	978-1-4051-2216-0 / 9781405122160
Zustand	Neuware