Studies on Graphene-Based Nanomaterials for Biomedical Applications (eBook)

Je Min Yoo (Autor)

eBook Download: PDF

2020 | 1st ed. 2020
XXIV, 68 Seiten
Springer Singapore (Verlag)
978-981-15-2233-8 (ISBN)

Infos

This thesis presents various applications of graphene-based nanomaterials, especially in biomedicine. Graphene and its derivatives have gained enormous attention from scientists in all fields of study due to many unprecedented properties. The initial scientific attention was focused on the development of transparent flexible electrodes by exploiting two-dimensional graphene film's extraordinary electrical and physical properties. Recently, given an increasing evidence of dispersed graphene-based nanomaterials' biocompatibility, researchers have endeavored to employ these materials in other studies relevant to biomedical technologies.

In this respect, the thesis provides a comprehensive review on the synthesis, toxicity, and a few of the key biomedical applications in the first chapter. The following chapter discusses the use of a graphene film as a novel catalyst to oxidatively destroy phenols, which are known to be potentially mutagenic and carcinogenic. Finally, and most importantly, the last chapter introduces the therapeutic role of graphene quantum dots, the smallest graphene-based nanomaterials, for Parkinson's disease. The results are promising for the use of graphene quantum dots as the basis of future clinical drug candidates for neurodegenerative disorders. 

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​Je Min Yoo earned a PhD degree in the Department of Chemistry, Seoul National University, Republic of Korea in 2019. His research interests focus on various biomedical application  of graphene technology.

Inhalt

Supervisor’s Foreword 6
Preface 8
Parts of this dissertation have been published in the following journals: 10
Acknowledgements 11
Contents 13
List of Figures 15
1 Introduction of Graphene-Based Nanomaterials 25
1.1 Applications in Biology and Medical Science 25
1.1.1 Sensing Applications 26
1.1.2 Therapeutic Applications 27
1.1.3 Fluorescence Bio-imaging 27
1.2 Preparation of Graphene-Based Nanomaterials 29
1.2.1 Enhancing the Stability Under Physiological Conditions 30
1.2.2 Reduction of GOs 30
1.3 Toxicity of Graphene-Based Nanomaterials 31
1.3.1 In Vitro Toxicity of Graphene-Based Nanomaterials 31
1.3.2 In Vivo Toxicity of Graphene-Based Nanomaterials 32
1.3.3 Biodegradation of Graphene-Based Nanomaterials 34
1.4 Perspectives and Other Applications 34
References 36
2 Catalytic Degradation of Phenols by Recyclable CVD Graphene Films 38
2.1 Summary 38
2.2 Introduction 38
2.3 Results and Discussion 39
2.4 Conclusion 45
2.5 Experimental 45
Supplementary Information 46
References 49
3 Graphene Quantum Dots Prevent ?-Synucleinopathy in Parkinson’s Disease 51
3.1 Summary 51
3.2 Introduction 51
3.3 Results and Discussion 52
3.4 Conclusion 62
3.5 Experimental 62
Supplementary Information 70
References 86
Appendix 87

Produkt-Details

• Erscheint lt. Verlag: 8.1.2020
• Reihe/Serie: Springer Theses
• Reihe/Serie: Springer Theses
• Zusatzinfo: XXIV, 68 p. 31 illus., 27 illus. in color.
• Sprache: englisch
• Themenwelt: Medizin / Pharmazie ► Pflege
• Themenwelt: Medizin / Pharmazie ► Physiotherapie / Ergotherapie ► Orthopädie
• Themenwelt: Naturwissenschaften ► Physik / Astronomie ► Festkörperphysik
• Themenwelt: Technik ► Elektrotechnik / Energietechnik
• Themenwelt: Technik ► Maschinenbau
• Themenwelt: Technik ► Medizintechnik
• Schlagworte: Catalytic Degradation of Phenols • Fluorescence Bio-Imaging • Graphene-based Nanomaterials • Graphene Quantum Dots • Recyclable CVD Grapehene Films • α-synucleinopathy
• ISBN-10: 981-15-2233-2 / 9811522332
• ISBN-13: 978-981-15-2233-8 / 9789811522338