G Protein-Coupled Receptors

Structure, Function, and Ligand Screening

Tatsuya Haga, Shigeki Takeda (Herausgeber)

Buch | Softcover

336 Seiten

2019
CRC Press (Verlag)
978-0-367-39237-6 (ISBN)

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This book provides a broad base of knowledge of G-protein-coupled receptors. Useful at both the university and industrial levels, this book is of particular interest to those who are developing therapeutic approaches to diseases using drugs that influence receptor activation.

Tatsuya Haga, Shigeki Takeda

Screening of Ligands for GPCRs. Screening of Endogenous Ligands for Orphan GPCRs. Screening of Ligands for Human GPCRs by the Use of Receptor-Ga Fusion Proteins. Screening and Identification of Ghrelin, an Endogenous Ligand for the Growth-Hormone-Secretagogue Receptor. Ligand Screening of Olfactory Receptors. Functions and Regulation of GPCRs. Generation and Phenotypical Analysis of Muscarinic Acetylcholine Receptor Knockout Mice. Systematic Mutagenesis of M1 Muscarinic Acetylcholine Receptors. Analysis of the Regulation of Muscarinic Acetylcholine Receptors. Single-Molecule Analysis of Chemotactic Signaling Mediated by cAMP Receptor on Living Cells. Oligomerization of G Protein-Coupled Purinergic Receptors. Tertiary Structure of GPCRs and their Ligands. Methods and Results in X-ray Crystallography of Bovine Rhodopsin. Determination of Steric Structure of Muscarinic Ligands Bound to Muscarinic Acetylcholine Receptors: Approaches by TRNOE (Transferred Nuclear Overhauser Effect). Modeling of G Protein-Coupled Receptors for Drug Design.

Erscheinungsdatum	24.09.2019
Verlagsort	London
Sprache	englisch
Maße	156 x 234 mm
Gewicht	620 g
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie
Themenwelt	Naturwissenschaften ► Biologie ► Biochemie
ISBN-10	0-367-39237-2 / 0367392372
ISBN-13	978-0-367-39237-6 / 9780367392376
Zustand	Neuware