Enantioselective Synthesis of Beta-Amino Acids
Seiten
1996
|
New edition
John Wiley & Sons Inc (Verlag)
978-0-471-18627-4 (ISBN)
John Wiley & Sons Inc (Verlag)
978-0-471-18627-4 (ISBN)
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This book presents an overview of the importance of beta-amino acids in pharmaceutical sciences, and discusses the most important methods that have been developed for the preparation of enantiomerically pure compounds. Each method is described by the organic chemist who developed it.
This book presents an overview of the importance of beta-amino acids in pharmaceutical sciences, and discusses the most important methods that have been developed for the preparation of enantiomerically pure compounds. Each method is described by the organic chemist who developed it, and so will be written with authoritative, first-hand knowledge. This title is the first book to summarize new available methodologies for preparing beta-amino acids in optically pure form, a recent development in this field. The title also provides methods for synthesizing optically pure precursors to pharmacologically active substances, including beta-lacatams.
This book presents an overview of the importance of beta-amino acids in pharmaceutical sciences, and discusses the most important methods that have been developed for the preparation of enantiomerically pure compounds. Each method is described by the organic chemist who developed it, and so will be written with authoritative, first-hand knowledge. This title is the first book to summarize new available methodologies for preparing beta-amino acids in optically pure form, a recent development in this field. The title also provides methods for synthesizing optically pure precursors to pharmacologically active substances, including beta-lacatams.
Partial table of contents:; The Medicinal Chemistry of beta--Amino Acids: Paclitaxel as an Illustrative Example (T. Boge & G. Georg).; Biological Activity of beta--Amino Acids and beta--Lactams (J. Tamariz).; Selective Transformations of N,N--Dibenzyl Protected Asparagine and Aspartic Acid Derivatives (P. Gmeiner).; Synthesis of Nonracemic beta--Amino Acids via Chiral Sulfinimines (F. Davis & R. Reddy).; Enantioselective Synthesis of beta--Amino Acids via 6--Substituted Perhydropyrimidin--4--Ones (G. Cardillo & C. Tomasini).; Efficient Stereoselective Preparation of the Taxol Phenylisoserine Side Chain (A. Koskinen & E. Karvinen).; Chemoenzymatic Synthesis of the Side Chain of Taxol (C. Sih).; Index.
| Erscheint lt. Verlag | 8.4.1997 |
|---|---|
| Zusatzinfo | index |
| Verlagsort | New York |
| Sprache | englisch |
| Maße | 240 x 160 mm |
| Gewicht | 879 g |
| Einbandart | gebunden |
| Themenwelt | Naturwissenschaften ► Biologie ► Biochemie |
| Naturwissenschaften ► Chemie ► Organische Chemie | |
| ISBN-10 | 0-471-18627-9 / 0471186279 |
| ISBN-13 | 978-0-471-18627-4 / 9780471186274 |
| Zustand | Neuware |
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