Down Syndrome and Alzheimer Disease
John Wiley & Sons Inc (Verlag)
978-0-471-58841-2 (ISBN)
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Over the last decade, biomedical researchers have documented that individuals with Downs syndrome have a markedly high probability of developing Alzheimer disease in later life. This book presents a comprehensive overview of current research efforts aimed at understanding the behavioural, neuropathological, and genetic correlations between Downs syndrome and Alzheimer disease. As a survey of current knowledge on the subject, the book includes both clinical analyses and experimental approaches to offer a full perspective on the subject.
ALZHEIMER DISEASE IN DOWN SYNDROME: The Neurology of Alzheimer Disease in Down Syndrome; Longitudinal Study of Neuropsychological Function in Older Adults With Down Syndrome; Dementia in Down Syndrome: Methods of Evaluation; Parallels Between Down Syndrome Dementia and Alzheimer's Disease; Down Syndrome: Differentiating Mental Retardation and Dementia With Brain Imaging Techniques; Down Syndrome as a Key to the Time Sequence of Brain Changes in Alzheimer Disease; RELATIONSHIP OF CHROMOSOME 21 TO ALZHEIMER DISEASE AND AMYLOID: Amyloid Precursor Protein (APP) and A4 Amyloid in Alzheimer's Disease and Down Syndrome; Mutations in APP and Their Role in beta-Amyloid Deposition; MODEL SYSTEMS AND PATHOGENETIC MECHANISMS: Neurodegeneration and Gene Dysregulation: Studies Utilizing the Mouse Trisomy 16 Model of Down Syndrome; Alzheimer's Disease-Type Brain Abnormalities in Animal Models; Potential Role of S100-beta in Alzheimer's Disease: An Hypothesis Involving Mitotic Protein Kinases. @21 YC4, S
| Erscheint lt. Verlag | 24.11.1992 |
|---|---|
| Reihe/Serie | Progress in Clinical & Biological Research ; v. 379 |
| Zusatzinfo | Ill. |
| Verlagsort | New York |
| Sprache | englisch |
| Maße | 156 x 235 mm |
| Gewicht | 652 g |
| Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Geriatrie |
| Medizin / Pharmazie ► Medizinische Fachgebiete ► Neurologie | |
| Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie | |
| ISBN-10 | 0-471-58841-5 / 0471588415 |
| ISBN-13 | 978-0-471-58841-2 / 9780471588412 |
| Zustand | Neuware |
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