Glucosinolates

Jean-Michel Mérillon, Kishan Gopal Ramawat (Herausgeber)

Buch | Hardcover

XIV, 473 Seiten

2017 | 2017
Springer International Publishing (Verlag)
978-3-319-25461-6 (ISBN)

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This is the first comprehensive reference compilation on the substance class of glucosinolates. This handbook introduces the reader to the sulfur-containing glucosinolates (S-glucosides), a class of secondary metabolites of almost all plants of the order Capparales, in particular in the family Brassicaceae (e.g. broccoli and other cabbages), derived from glucose and an amino acid. The book illustrates the natural variety of glucosinolate structures, mainly derived from the precursor amino acid. Chapters describe the resulting rich bioactivity of the glucosides, for example as anti-cancer agents, insecticides, nematicides, fungicides, their potential phytotoxic effects, antimicrobial activity and their possible role in neurodegenerative diseases and human health. Different methods for the extraction, characterization, quantification and processing of the glucosinolates are introduced, and potential applications are discussed. The fate of glucosinolates during food processing is also briefly addressed. This handbook is written by leading experts and structured in different sections addressing the natural occurrence of glucosinolates, their (bio-)synthesis, bioactivity, food processing of glucosinolate-containing vegetables, health and disease-related aspects, biotechnology, and methods applied in glucosinolate-research. It is thus a rich reference source for every reader working in the field, from chemists and biotechnologists, to life scientists, pharmacists and medical scientists.

Prof. Dr. Kishan G. Ramawat is Former Professor & Head of the Botany Department, M.L. Sukhadia University, Udaipur, India, and can look back on longstanding research experience. He received his Ph.D. in Plant Biotechnology in 1978 from the University of Jodhpur, India and afterwards joined the university as a faculty member. In 1991 he moved to the M.L.Sukhadia University in Udaipur as Associate Professor and became Professor in 2001. He served as the Head of the Department of Botany (2001-2004, 2010-2012), was in charge of the Department of Biotechnology (2003-2004), was a member of the task force on medicinal and aromatic plants of the Department of Biotechnology, Government of India, New Delhi (2002-2005) and coordinated UGC-DRS and DST-FIST programmes (2002-2012). Prof. Ramawat had done his postdoctoral studies at the University of Tours, France from 1983-85, and later returned to Tours as visiting professor (1991). He also visited the University of Bordeaux 2, France several times as visiting professor (1995, 1999, 2003, 2006, 2010), and in 2005 Poland in an academic exchange programme (2005). Through these visits in France, Prof. Ramawat and Prof. Mérillon established a strong connection, which has resulted in productive collaborations and several book and reference work publications. Prof. Ramawat has published more than 170 well cited peer reviewed papers and articles, and edited several books and reference works on topics such as the biotechnology of medicinal plants, secondary metabolites, bioactive molecules, herbal drugs, and many other topics. His research was funded by several funding agencies. In his research group, Prof. Ramawat has supervised doctoral thesis of 25 students. He is an active member of several academic bodies, associations and editorial boards of journals.

Part I Occurrence: Glucosinolates: an Overview.- Glucosinolates: Novel Sources and Biological Potential.- Glucosinolates: a Brief overview over their Chemistry and Biological Activities.- Health-Promoting Compounds of Broccoli.- Genetic analysis of Glucosinolate Variability in Broccoli.- Glucosinolates in the Endemic Plants of the Tribe Alysseae (Brassicaceae) Wild-Growing in Croatia.- Part II (Bio)Synthesis: Costs of Glucosinolates in Brassica Rapa.- The Significance of Glucosinolates for Sulfur Storage in Brassicaceae Seedlings.- The Influence of Environment and Process Parameters on Glucosinolate-Myrosinase System from Brassica.- Control of Glucosinolates in Plants by Environmental Factors (Light).- Part III Bioactivity: Glucosinolates and Plant Defence.- Glucosinolates and Leaf-Chewing Herbivores.- Insect Attraction versus Plant Defense.- The role of Glucosinolates in Resistance against Molluscan Herbivores.- Glucosinolates Interactions with Herbivores and their Natural Enemies.- Transport of Defense Compounds: Glucosinolates.- Control of Postharvest Disease by Glucosinolates.- Turning the 'Mustard Oil Bomb' into A 'Cyanide Bomb': Aromatic Glucosinolate Metabolism in A Specialist Insect Herbivore.- Glucosinolates and their Nematicidal Activity.- Glucosinolate and Isothiocyanate Production in A Plasticulture Production System.- Part IV Food Processing: The Fate of Glucosinolates During Thermal Processing of Vegetables.- Influence of Fermentation on Glucosinolates and Glucobrassicin Degradation Products in Sauerkraut.- Part V Health and Diseases: Glucosinolates in Health and Diseases.- Protection of Humans by Plant Glucosinolates.- Glucosinolates as Antioxidants?.- Glucosinolates and Bone formation.- Glucosinolates as Nutraceuticals.- Glucosinolates and Cholesterol Gallstones.- Glucosinolates and Bioavailibility - Isothiocyanates.- Antimicrobial Activities of Isothiocyanates.- The Role of Glucosinolate-Containing Vegetables in Cancer Prevention and their Promotion in Clinical Practice.- Glucosinolates and Chemopreventive Activity.- Detoxication of Airborne Pollutants by Broccoli Sprouts.- Antibacterial Activity of Glucosinates in Humans.- Anti-inflammatory Activity of Sulforaphane.- Chemopreventive Activity of Sulforaphane and Mechanisms of Action.- Sulforaphane: Antitumor Effects and Induction of Apoptosis.- Sulforaphane and Neuroprotection.- Sulphoraphane and Diabetes.- Sulphoraphane and Atherosclerosis.- Clinical and Molecular Evidence of the Consumption of Broccoli, Glucoraphanin and Sulforaphane in Humans.- Part VI Biotechnology: Metabolic Engineering of Aliphatic Glucosinolates in Hairy Root Cultures.- Biotic Elicitors Effectively increase the Glucosinolates Content.- The Physiological Importance of Glucosinolates on Plant Response to Abiotic Stress.- Sucrose Enhances the Accumulation of anthocyanins and Glucosinolates in Broccoli Sprouts.- Enhancement of Glucosinolate and Sulforaphane Formation of Broccoli Sprouts by Zinc Sulphate via its Stress Effect.- Reactivity and Stability of Glucosinolates and their Breakdown Products in Foods.- Part VII Methods: Extraction and Characterization of Glucosinolates.- Analytical Methods for Determining Bioavailability and Bioaccessibility of Bioactive Compounds from Fruits and Vegetables: Glucosinolates.- Phytochemical Fingerprinting for Simultaneous Identification of Glucosinolates and Phenolics.- Major and Minor Glucosinolates by Mass Spectrometry.- Quantification of Plant Surface Metabolites by Matrix-Assisted Laser Desorption-Ionization Mass Spectrometry Imaging: Glucosinolates on Arabidopsis Thaliana Leaves.- Quantification of Glucosinolates by Reverse-Phase Liquid Chromatography.- Glucosinolates: Extraction and Methods of Analysis from Paper Chromatography to Microchip analysis.- Spectrophotometric Method for Quantification of Total Glucosinolates.- The Use of 'Omics Technologies in Brassicaceous Vegetables.

Erscheinungsdatum	12.05.2017
Reihe/Serie	Reference Series in Phytochemistry
Zusatzinfo	XIV, 473 p. 83 illus., 49 illus. in color.
Verlagsort	Cham
Sprache	englisch
Maße	155 x 235 mm
Themenwelt	Naturwissenschaften ► Biologie ► Biochemie
Themenwelt	Naturwissenschaften ► Chemie ► Organische Chemie
Schlagworte	Anthocyanins broccoli sprouts • bioorganic chemistry • Brassicaceae plants biochemistry • Broccoli health promotion • Chemistry and Materials Science • Chromatography phytochemical compounds • Enzymatic activation glucosinolates • food science • Health promotion cruciferous vegetables • medical biochemistry • Mustard oils • Pharmacology/Toxicology • Phytochemical fingerprinting • plant biochemistry • Plant Breeding/Biotechnology • secondary metabolites • S-glucosides • Sulforaphane
ISBN-10	3-319-25461-8 / 3319254618
ISBN-13	978-3-319-25461-6 / 9783319254616
Zustand	Neuware