Pharmaceutical Substances, 5th Edition, 2009 (eBook)

Syntheses, Patents and Applications of the most relevant APIs

Jürgen Engel, Axel Kleemann, Bernhard Kutscher, Dietmar Reichert (Autoren)

eBook Download: PDF

2014 | 5. Auflage
1800 Seiten
Georg Thieme Verlag KG
978-3-13-179275-4 (ISBN)

Infos

'Pharmaceutical Substances' is a compendium of 1,300 of the most significant pharmaceutical compounds that are of interest to the chemical and pharmaceutical industries. It is the ideal companion to the 'Pharmaceutical Substances Online Edition' and an authoritative resource for everyone involved in design, discovery, development, evaluation, and marketing of drugs. Profs. Axel Kleemann, Jürgen Engel, Bernhard Kutscher, and Dr. Dietmar Reichert present in a clear and concise manner highly evaluated information collected from all the relevant literature, and commercial patent data. This includes synthetic routes and all intermediates for approved drugs from the six most important markets. All compounds are organized alphabetically according to their International Non-proprietary Name (INN). The book features four indexes: Trade Names / Intermediates / Enzymes, Microorganisms, Plants, and Animal Tissues / Substance Classes. // The content of this e-book was originally published in 2009.

Inhalt

Axel Kleemann, Jürgen Engel, Bernhard Kutscher et al.: Pharmaceutical Substances – Syntheses, Patents and Applications of the most relevant AIPs 1
Title page 4
Imprint 5
Table of Contents 6
Preface to the fifth printed edition 7
Introduction 8
Sample Entry Pharmaceutical Substances 5th edition 9
Alphabetical List of Drug Monographs 11
A 34
Abacavir 34
Abarelix 38
Acamprosate calcium 39
Acarbose 40
Acebutolol 40
Aceclofenac 42
Acemetacin 42
Acepromazine 44
Acetazolamide 44
Acetylcholine chloride 45
Acetylcysteine 46
ß-Acetyldigoxin 47
Acetylsalicylic acid 49
Aciclovir 50
Aclatonium napadisilate 53
Acrivastine 54
Adefovir dipivoxil 56
Ademetionine 57
Adrafinil 58
Ajmaline 59
Alacepril 59
Albendazole 60
Alclometasone dipropionate 61
Alcuronium chloride 62
Alendronate sodium 63
Alfacalcidol 65
Alfentanil 66
Alfuzosin 68
Aliskiren 69
Alitretinoin 72
Alizapride 74
Allantoin 74
Allopurinol 76
Alminoprofen 77
Almotriptan 78
Alosetron hydrochloride 79
Alprazolam 81
Amantadine 82
Ambrisentan 83
Ambroxol 84
Amcinonide 85
Amezinium metilsulfate 86
Amidotrizoic acid 87
Amifostine 88
Amikacin 89
Amiloride 91
Aminocaproic acid 92
5-Aminolevulinic acid 92
p-Aminosalicylic acid 93
Amiodarone 94
Amisulpride 95
Amitriptyline 96
Amitriptylinoxide 98
Amlodipine 98
Amorolfine 100
Amoxapine 100
Amoxicillin 101
Amphotericin B 104
Ampicillin 105
Amprenavir 108
Anagrelide hydrochloride 110
Anastrozole 112
Antazoline 113
Apomorphine 113
Apraclonidine 114
Aprepitant 115
Argatroban 118
Aripiprazole 120
Articaine 121
Ascorbic acid 121
Asparaginase 123
L-Aspartic acid 123
Atazanavir sulfate 124
Atenolol 126
Atorvastatin calcium 127
Atosiban 134
Atovaquone 136
Atracurium besilate 137
Atropine 138
Auranofin 139
Azacitidine 140
Azatadine 141
Azathioprine 142
Azelaic acid 143
Azelastine 144
Azithromycin 145
Aztreonam 147
B 150
Bacitracin 150
Baclofen 151
Balsalazide sodium 152
Bambuterol 153
Barnidipine 153
Beclometasone 155
Befunolol 156
Bekanamycin 157
Benazepril 158
Bendamustine hydrochloride 159
Bendazac 160
Bendroflumethiazide 161
Benfotiamine 162
Benidipine 162
Benperidol 163
Benproperine 164
Benserazide 165
Benzalkonium chloride 166
Benzathine benzylpenicillin 167
Benzocaine 167
Benzonatate 168
Benzoyl peroxide 168
Benzydamine 169
Benzyl benzoate 170
Benzylpenicillin 171
Betacarotene 171
Betahistine 175
Betaine aspartate 175
Betaine hydrate 176
Betamethasone 177
Betamethasone dipropionate 181
Betamethasone valerate 181
Betaxolol 182
Bethanechol chloride 183
Bexarotene 184
Bezafibrate 185
Bibrocathol 186
Bicalutamide 186
Bifonazole 188
Bimatoprost 189
Biotin 190
Biperidene 193
Bisacodyl 194
Bisoprolol 195
Bitolterol 196
Bivalirudin 197
Bleomycin 198
Bornaprine 198
Bortezomib 199
Bosentan 201
Brimonidine 202
Brinzolamide 203
Brivudine 206
Bromazepam 207
Bromelain 209
Bromhexine 210
Bromocriptine 211
Bromperidol 212
Brompheniramine 212
Brotizolam 213
Bucillamine 214
Bucumolol 215
Budesonide 216
Budipine 217
Bufexamac 218
Buflomedil 219
Bumetanide 219
Bunazosin 220
Bupivacaine 221
Buprenorphine 222
Bupropion 224
Buserelin 225
Buspirone 226
Busulfan 227
Butalbital 228
Butenafine 228
Butorphanol 230
Butylscopolammonium bromide 231
C 233
Cabergoline 233
Cadralazine 234
Caffeine 235
Calcifediol 235
Calcipotriol 236
Calcitonin 239
Calcitriol 240
Calcium dobesilate 241
Calcium pantothenate 242
Camostat 244
Candesartan cilexetil 245
Capecitabine 247
Capreomycin 249
Captopril 249
Carbachol 252
Carbamazepine 253
Carbidopa 253
Carbimazole 255
Carbocisteine 256
Carboplatin 256
Carmofur 257
Carmustine 258
Carnidazole 259
Carpipramine 259
Carteolol 260
Carvedilol 261
Caspofungin acetate 262
Cefaclor 263
Cefadroxil 265
Cefalexin 266
Cefatrizine 268
Cefazolin 269
Cefbuperazone 270
Cefditoren pivoxil 272
Cefixime 273
Cefotaxime 277
Cefotiam 278
Cefoxitin 279
Cefpiramide 282
Ceftazidime 283
Ceftriaxone 286
Cefuroxime 288
Celecoxib 290
Celiprolol 291
Ceruletide 292
Cetirizine 294
Cetrimonium bromide 295
Cetrorelix 295
Cetylpyridinium chloride 298
Cevimeline hydrochloride 298
Chenodeoxycholic acid 299
Chloral hydrate 301
Chlorambucil 301
Chloramphenicol 302
Chlordiazepoxide 304
Chlorhexidine 305
Chlormadinone acetate 306
Chloroquine 307
Chlorphenamine 310
Chlorpromazine 311
Chlorprothixene 312
Chlortalidone 313
Chlortetracycline 315
Cibenzoline 316
Ciclesonide 316
Ciclopirox 317
Ciclosporin 318
Cidofovir 319
Cilastatin 320
Cilazapril 321
Cilostazol 323
Cimetidine 324
Cinacalcet hydrochloride 326
Cinchocaine 327
Cineole 328
Cinnarizine 328
Ciprofibrate 329
Ciprofloxacin 330
Cisatracurium besylate 333
Cisplatin 334
Citalopram 335
Citicoline 337
Cladribine 338
Clarithromycin 340
Clavulanic acid 342
Clebopride 344
Clemastine 345
Clenbuterol 346
Clindamycin 348
Clioquinol 349
Clobazam 349
Clobetasol propionate 350
Clobetasone butyrate 351
Clocortolone 352
Clodronate disodium 353
Clomethiazole 354
Clomifene 355
Clomipramine 356
Clonazepam 357
Clonidine 358
Clopamide 359
Clopidogrel hydrogensulfate 359
Cloprednol 362
Clorazepate dipotassium 363
Clorprenaline 364
Clotrimazole 364
Clozapine 366
Cocarboxylase 367
Codeine 367
Colecalciferol 368
Colesevelam hydrochloride 369
Colestipol hydrochloride 370
Colestyramine 370
Colforsin dapropate 371
Colfosceril palmitate 372
Colistin 372
Cortisone 373
Coumarin 376
Croconazole 376
Cromoglicic acid 377
Crotamiton 378
Cyanocobalamin 379
Cyclobenzaprine 381
Cyclopentolate 381
Cyclophosphamide 382
Cycloserine 383
Cyproheptadine 383
Cyproterone acetate 384
Cytarabine 386
Cytidine 387
D 389
Dabigatran etexilate 389
Dacarbazine 390
Dactinomycin 391
Dalteparin sodium 392
Danaparoid sodium 393
Dantrolene 394
Dapsone 394
Darifenacin 396
Dasatinib 397
Daunorubicin 398
Deferasirox 399
Deferiprone 400
Deferoxamine 401
Deflazacort 402
Delapril 403
Delavirdine mesilate 404
Demeclocycline 406
Dequalinium chloride 407
Desflurane 407
Desipramine 409
Desloratadine 410
Desmopressin 411
Desogestrel 414
Desoximetasone 415
Dexamethasone 416
Dexamethasone 21-isonicotinate 419
Dexamethasone phosphate 419
Dexchlorpheniramine 420
Dexketoprofen trometamol 421
Dexmethylphenidate hydrochloride 422
Dexpanthenol 423
Dexrazoxane 423
Dextromethorphan 424
Diacerein 425
Diazepam 426
Diazoxide 428
Diclofenac 429
Dicloxacillin 430
Didanosine 431
Diflorasone diacetate 432
Diflucortolone valerate 433
Diflunisal 435
Difluprednate 435
Digitoxin 436
Digoxin 437
Dihydralazine 439
Dihydrocodeine 439
Dihydroergotamine 440
Dihydroergotoxine 441
Dihydrotachysterol 442
Diltiazem 442
Dimenhydrinate 446
Dimethicone 446
Dimetindene 447
Dinoprostone 448
Diosmin 449
Diphenhydramine 449
Dipivefrine 450
Dipyridamole 451
Distigmine bromide 453
Disulfiram 453
Dithranol 454
Dobutamine 455
Docetaxel 455
Dolasetron mesilate 463
Domperidone 465
Donepezil hydrochloride 467
Dopamine 467
Dopexamine 468
Dornase alfa 469
Dorzolamide 469
Dosulepin 471
Doxapram 472
Doxazosin 472
Doxepin 473
Doxercalciferol 474
Doxifluridine 476
Doxorubicin 477
Doxycycline 478
Doxylamine 480
Dronabinol 481
Droperidol 482
Drospirenone 482
Duloxetine oxalate 484
Dutasteride 486
Dydrogesterone 488
E 489
Ebastine 489
Econazole 489
Edrophonium chloride 490
Efavirenz 491
Eflornithine 494
Efonidipine hydrochloride ethanol 494
Elcatonin 497
Eletriptan 498
Emedastine 500
Emtricitabine 500
Enalapril 502
Enalaprilat 505
Enflurane 505
Enfuvirtide 506
Enoxacin 508
Enoxaparin sodium 509
Enoximone 509
Entacapone 510
Entecavir 511
L(–)-Ephedrine 513
Epinastine hydrochloride 514
Epinephrine 515
Epirubicin 516
Eplerenone 519
Epoprostenol 522
Eprosartan 523
Eptifibatide 527
Ergocalciferol 530
Ergotamine 531
Erlotinib hydrochloride 531
Ertapenem 534
Erythromycin 536
Erythromycin ethylsuccinate 537
Erythromycin lactobionate 538
Escin 539
Escitalopram oxalate 540
Esmolol 542
Esomeprazole 543
Estazolam 545
Estradiol 546
Estradiol benzoate 548
Estradiol valerate 548
Estramustine phosphate 549
Estriol 550
Eszopiclone 551
Ethacridine 552
Ethambutol 553
Ethinylestradiol 555
Ethionamide 556
Ethosuximide 557
Etidronic acid 557
Etilefrine 558
Etodolac 559
Etofenamate 560
Etofibrate 560
Etomidate 561
Etopophos 562
Etoposide 563
Etoricoxib 564
Etravirine 566
Everolimus 567
Exemestane 568
Exenatide 570
Ezetimibe 571
F 575
Fadrozole 575
Famciclovir 576
Famotidine 577
Febuprol 578
Felbamate 578
Felodipine 580
Felypressin 581
Fenipentol 582
Fenofibrate 582
Fenoprofen 583
Fenoterol 584
Fentanyl 585
Fenticonazole 586
Fexofenadine hydrochloride 587
Finasteride 590
Flavoxate 591
Flecainide 592
Flomoxef 592
Flucloxacillin 594
Fluconazole 595
Flucytosine 597
Fludarabine phosphate 598
Fludrocortisone 599
Flumazenil 600
Flumetasone 601
Flunarizine 603
Flunisolide 604
Flunitrazepam 605
Fluocinolone acetonide 606
Fluocinonide 607
Fluocortolone 608
Fluocortolone trimethylacetate 609
Fluorescein 610
Fluorometholone 610
Fluorouracil 611
Fluoxetine 613
Flupentixol 616
Fluphenazine 617
Flupirtine 618
Fluprednidene acetate 619
Flurazepam 621
Flurbiprofen 622
Fluspirilene 624
Flutamide 624
Fluticasone propionate 626
Fluvastatin sodium 627
Fluvoxamine 630
Folic acid 630
Folinic acid 632
Fomepizole 633
Fondaparinux sodium 634
Formoterol 638
Fosamprenavir 639
Foscarnet sodium 640
Fosfomycin 641
Fosinopril 642
Framycetin 644
Frovatriptan 645
Fulvestrant 647
Furosemide 648
G 650
Gabapentin 650
Gabexate 652
Gadobenic acid 653
Gadobutrol 654
Gadodiamide 656
Gadopentetic acid 657
Gadoteric acid 658
Gadoteridol 658
Gadoversetamide 659
Galantamine 660
Gallopamil 663
Ganciclovir 664
Ganirelix acetate 666
Gatifloxacin 667
Gefitinib 667
Gemcitabine 668
Gemfibrozil 672
Gentamicin 673
Gestodene 674
Glibenclamide 675
Gliclazide 676
Glimepiride 677
Glipizide 678
Gliquidone 679
D-Glucosamine 680
Glutathione 681
Glycopyrronium bromide 682
Gonadorelin 682
Goserelin acetate 683
Granisetron 685
Griseofulvin 686
Guaiazulene 687
Guaifenesin 688
Guanethidine sulfate 689
Gusperimus trihydrochloride 689
H 693
Halometasone 693
Haloperidol 693
Heparin 694
Hexetidine 696
L-Histidine 697
Homatropine methylbromide 697
Hyaluronic acid 698
Hydralazine 699
Hydrochlorothiazide 700
Hydrocodone 701
Hydrocortisone 702
Hydrocortisone acetate 705
Hydrocortisone 17-butyrate 706
Hydromorphone 707
Hydroxocobalamin 707
Hydroxycarbamide 708
Hydroxychloroquine 709
Hydroxyethyl salicylate 710
Hydroxyprogesterone caproate 710
Hydroxyzine 712
Hymecromone 713
I 714
Ibandronate sodium monohydrate 714
Ibuprofen 714
Ibuprofen lysinate 718
Idarubicin 718
Idebenone 720
Idoxuridine 721
Ifosfamide 722
Iloprost 723
Imatinib 725
Imidapril 726
Imipenem 728
Imipramine 734
Imiquimod 734
Indanazoline 739
Indapamide 740
Indinavir sulfate 740
Indometacin 746
Indoramin 748
Inositol nicotinate 749
Iobitridol 749
Iodixanol 750
Iohexol 751
Iomeprol 752
Iopamidol 753
Iopromide 754
Iotrolan 754
Iotroxic acid 756
Ioxaglic acid 756
Ioxitalamic acid 757
Ipratropium bromide 758
Irbesartan 759
Irinotecan 761
Isepamicin 762
Isoconazole 763
Isoflurane 764
Isoniazid 765
Isosorbide dinitrate 765
Isosorbide mononitrate 766
Isotretinoin 767
Isradipine 769
Itraconazole 770
Ivabradine 772
Ixabepilone 774
J 776
Josamycin 776
K 777
Kanamycin (A) 777
Ketamine 777
Ketoconazole 778
Ketoprofen 779
Ketorolac 780
Ketotifen 782
L 785
Labetalol 785
Lacidipine 786
Lactulose 787
Lamivudine 788
Lamotrigine 792
Lanreotide 793
Lansoprazole 794
Lapatinib 795
Latamoxef 797
Latanoprost 800
Leflunomide 802
Lenalidomide 803
Lentinan 804
Lercanidipine hydrochloride 805
Letrozole 807
Leuprorelin acetate 808
Levamisole 811
Levetiracetam 814
Levobunolol 815
Levobupivacaine hydrochloride 816
Levocabastine 818
Levocarnitine 819
Levocetirizine 822
Levodopa 824
Levofloxacin 827
Levomepromazine 831
Levonorgestrel 832
Levosalbutamol 833
Levothyroxine 835
Lidocaine 836
Linezolid 837
Liothyronine 839
Lisinopril 840
Lisuride 842
Lofepramine 843
Lomefloxacin 844
Lomustine 845
Loperamide 846
Lopinavir 847
Loratadine 848
Lorazepam 851
Lormetazepam 852
Lornoxicam 853
Losartan potassium 854
Lovastatin 858
Loxapine 859
Loxoprofen 860
Lynestrenol 860
M 862
Magaldrate 862
Manidipine 862
Maprotiline 863
Maraviroc 864
Mebendazole 866
Mebeverine 867
Meclozine 868
Medazepam 868
Medrogestone 870
Medroxyprogesterone acetate 872
Mefenamic acid 873
Mefloquine 874
Mefruside 876
Megestrol acetate 876
Meloxicam 877
Melperone 878
Melphalan 879
Memantine 880
(–)-Menthol 881
Mephenesin 882
Mepivacaine 883
Meprobamate 884
Meptazinol 884
Mequitazine 885
Mercaptopurine 886
Meropenem 886
Mesalazine 889
Mesna 891
Mestranol 892
Mesuximide 893
Metamizole sodium 893
Metaxalone 894
Metformin 895
Methadone 896
Methenamine 897
Methocarbamol 898
Methohexital 899
Methotrexate 899
Methoxsalen 902
Methyldopa 903
Methylergometrine 904
Methylphenidate 905
Methylprednisolone 906
Methyltestosterone 908
Methylthioninium chloride 909
Metildigoxin 909
Metipranolol 910
Metirosine 911
Metixene 913
Metoclopramide 914
Metolazone 915
Metoprolol 916
Metronidazole 917
Mexiletine 918
Mezlocillin 919
Mianserin 920
Micafungin 921
Miconazole 922
Micronomicin 923
Midazolam 924
Midecamycin 926
Midodrine 926
Mifepristone 927
Miglitol 928
Milnacipran hydrochloride 929
Milrinone 932
Miltefosine 933
Minocycline 934
Minoxidil 935
Mirtazapine 937
Misoprostol 938
Mitomycin 940
Mitotane 940
Mitoxantrone 941
Mizolastine 942
Moclobemide 943
Modafinil 944
Moexipril 945
Molindone 947
Molsidomine 947
Mometasone furoate 948
Montelukast sodium 949
Morphine 953
Moxaverine 954
Moxifloxacin hydrochloride 955
Moxisylyte 957
Moxonidine 958
Mupirocin 959
Mycophenolate mofetil 960
Mycophenolic acid 961
Myrtecaine 961
N 963
Nabumetone 963
Nadifloxacin 963
Nadolol 965
Nafarelin acetate 965
Naftidrofuryl 967
Naftifine 968
Nalbuphine 969
Nalidixic acid 970
Nalmefene 970
Naloxone 971
Naltrexone 972
Nandrolone decanoate 974
Naphazoline 974
Naproxen 975
Naratriptan 979
Natamycin 982
Nateglinide 982
Nebivolol 984
Nedocromil 985
Nelarabine 986
Nelfinavir mesylate 987
Neostigmine methylsulfate 991
Netilmicin 991
Nevirapine 992
Nicardipine 994
Nicergoline 995
Niclosamide 997
Nicorandil 998
Nicotinamide 998
Nicotinic acid 999
Nicotinic acid benzyl ester 1000
Nifedipine 1000
Niflumic acid 1001
Nifuratel 1002
Nilotinib 1003
Nilvadipine 1005
Nimesulide 1006
Nimodipine 1007
Nimustine 1008
Nisoldipine 1008
Nitazoxanide 1009
Nitisinone 1010
Nitrazepam 1011
Nitrendipine 1012
Nitrofural 1013
Nitrofurantoin 1014
Nitroxoline 1015
Nizatidine 1015
Nomegestrol acetate 1016
Nonoxinol 9 1017
Nordazepam 1018
Norelgestromin 1018
Norethisterone 1019
Norethisterone acetate 1020
Norethisterone enanthate 1021
Norfloxacin 1022
Norgestimate 1023
D-Norpseudoephedrine 1023
Nortriptyline 1024
Nystatin 1025
O 1027
Obidoxime chloride 1027
Octreotide 1027
Ofloxacin 1028
Olanzapine 1029
Olmesartan medoxomil 1031
Olopatadine 1032
Olsalazine sodium 1034
Omeprazole 1034
Ondansetron 1037
Opipramol 1038
Orciprenaline 1039
Orlistat 1040
Orotic acid 1049
Orphenadrine 1050
Oseltamivir 1051
Oxaceprol 1055
Oxacillin 1056
Oxaliplatin 1057
Oxandrolone 1058
Oxaprozin 1058
Oxazepam 1059
Oxcarbazepine 1060
Oxetacaine 1062
Oxiconazole 1063
Oxilofrine 1064
Oxitriptan 1065
Oxitropium bromide 1067
Oxprenolol 1068
Oxybuprocaine 1069
Oxybutynin 1070
Oxycodone 1071
Oxymetazoline 1071
Oxymorphone 1072
Oxytetracycline 1073
Oxytocin 1074
Ozagrel 1075
P 1076
Paclitaxel 1076
Paliperidone 1082
Palonosetron 1083
Pamidronic acid 1085
Pancuronium bromide 1086
Pantethine 1087
Pantoprazole sodium 1088
Paracetamol 1090
Parecoxib sodium 1091
Paricalcitol 1092
Paromomycin 1093
Paroxetine 1094
Pemetrexed 1098
Pemirolast 1099
Penbutolol 1101
Penciclovir 1101
D-Penicillamine 1103
Pentaerithrityl tetranitrate 1105
Pentamidine 1105
Pentazocine 1106
Pentostatin 1107
Pentoxifylline 1107
Pentoxyverine 1109
Perazine 1110
Pergolide 1110
Perindopril 1111
Perphenazine 1113
Pethidine 1114
Phenazopyridine 1114
Phenobarbital 1115
Phenoxybenzamine 1116
Phenoxymethylpenicillin 1117
Phenprocoumon 1118
Phentermine 1119
Phenylbutazone 1120
Phenylpropanolamine 1120
Phenytoin 1121
Phytomenadione 1122
Pilocarpine 1123
Pimecrolimus 1124
Pimozide 1125
Pindolol 1126
Pioglitazone 1126
Pipamperone 1128
Pipemidic acid 1129
Pipenzolate bromide 1130
Piperacillin 1131
Piracetam 1132
Pirarubicin 1133
Pirbuterol 1133
Pirenzepine 1135
Piretanide 1136
Piritramide 1137
Piroxicam 1137
Pitavastatin 1139
Podophyllotoxin 1143
Polymyxin B 1146
Posaconazole 1147
Potassium canrenoate 1151
Prajmalium bitartrate 1152
Pralidoxime iodide 1152
Pramipexole hydrochloride 1153
Pramocaine 1155
Pranlukast 1155
Pranoprofen 1157
Prasterone enanthate 1158
Pravastatin 1158
Prazepam 1160
Praziquantel 1161
Prazosin 1162
Prednicarbate 1164
Prednisolone 1164
Prednisolone sodium phosphate 1166
Prednisolone sodium succinate 1167
Prednisone 1167
Pregabalin 1168
Pridinol 1171
Prilocaine 1172
Primidone 1173
Probenecid 1173
Procaine 1174
Procarbazine 1175
Procaterol 1176
Prochlorperazine 1176
Procyclidine 1177
Progesterone 1178
Proglumetacin 1179
Proguanil 1180
Promestriene 1180
Promethazine 1181
Propafenone 1182
Propicillin 1183
Propiverine 1183
Propofol 1185
Propranolol 1185
Propylthiouracil 1186
Propyphenazone 1187
Proscillaridin 1188
Prothipendyl 1189
Protionamide 1189
Protirelin 1190
Proxymetacaine 1192
Pyrantel 1193
Pyrazinamide 1194
Pyridostigmine bromide 1194
Pyridoxine 1195
Pyrimethamine 1197
Pyritinol 1198
Pyrvinium embonate 1199
Q 1201
Quazepam 1201
Quetiapine fumarate 1202
Quinagolide hydrochloride 1204
Quinapril hydrochloride 1205
Quinidine 1208
Quinine 1209
Quinisocaine 1209
R 1211
Rabeprazole sodium 1211
Raloxifene hydrochloride 1212
Raltegravir potassium 1215
Raltitrexed 1216
Ramelteon 1218
Ramipril 1219
Ramosetron hydrochloride 1220
Ranimustine 1221
Ranitidine 1222
Ranolazine 1224
Rasagiline 1225
Rebamipide 1226
Reboxetine 1227
Remifentanil 1228
Repaglinide 1229
Repirinast 1232
Reproterol 1233
Reserpine 1234
Retinol 1235
Ribavirin 1239
Riboflavin 1240
Rifampicin 1242
Rifaximin 1243
Rilmazafone 1244
Rilmenidine 1245
Riluzole 1246
Rimantadine 1247
Rimexolone 1248
Rimonabant 1249
Risedronate sodium 1251
Risperidone 1251
Ritonavir 1254
Rivaroxaban 1257
Rivastigmine 1258
Rizatriptan benzoate 1259
Rocuronium bromide 1262
Ropinirole 1262
Ropivacaine hydrochloride 1264
Rosiglitazone 1265
Rosuvastatin calcium 1267
S 1270
Saccharin 1270
Salazosulfapyridine 1271
Salbutamol 1272
Salmeterol 1274
Saquinavir 1275
Sarpogrelate 1278
Saxagliptin 1279
Scopolamine 1280
Secretin 1281
Selegiline 1282
Seratrodast 1283
Sertaconazole 1284
Sertindole 1285
Sertraline 1287
Setiptiline 1290
Sevoflurane 1291
Sibutramine hydrochloride 1292
Sildenafil 1294
Silibinin 1296
Simvastatin 1297
Sirolimus 1298
Sitagliptin phosphate 1299
Sizofiran 1302
Sobrerol 1303
Sodium aurothiomalate 1303
Sodium picosulfate 1304
Solifenacin 1304
Somatostatin 1306
Sorafenib 1306
Sorbitol 1307
Sotalol 1308
Spiramycin 1309
Spirapril 1309
Spironolactone 1312
Stavudine 1314
Streptokinase 1318
Streptomycin 1318
Sucralfate 1319
Sufentanil 1320
Sulbactam 1321
Sulbenicillin 1322
Sulconazole 1322
Sulfacetamide 1323
Sulfadiazine 1324
Sulfadoxine 1325
Sulfalene 1326
Sulfamethoxazole 1327
Sulindac 1327
Sulpiride 1329
Sultiame 1330
Sultopride 1330
Sumatriptan 1331
Sunitinib malate 1332
Suplatast tosilate 1334
Suxamethonium chloride 1335
T 1337
Tacalcitol 1337
Tacrolimus 1338
Tadalafil 1344
Talinolol 1345
Talipexole 1346
Taltirelin 1347
Tamoxifen 1347
Tamsulosin hydrochloride 1350
Tandospirone 1352
Taurolidine 1353
Tazanolast 1354
Tazarotene 1355
Tegafur 1356
Tegaserod maleate 1357
Teicoplanin 1358
Telbivudine 1359
Telithromycin 1361
Telmesteine 1364
Telmisartan 1365
Temazepam 1366
Temocapril 1367
Temoporfin 1370
Temozolomide 1371
Temsirolimus 1373
Tenofovir disoproxil fumarate 1374
Tenoxicam 1376
Terazosin 1377
Terbinafine 1379
Terbutaline 1380
Terconazole 1381
Terfenadine 1383
Terlipressin 1383
Testosterone 1385
Testosterone enanthate 1386
Tetrabenazine 1387
Tetracaine 1388
Tetracycline 1388
Tetrazepam 1390
Tetryzoline 1391
Thalidomide 1391
Theophylline 1393
Theophylline ethylenediamine 1394
Thiamazole 1394
Thiamine 1395
Thiamphenicol 1397
Thioctic acid 1398
Thiopental 1399
Thioridazine 1400
Thiotepa 1400
Tiabendazole 1401
Tiadenol 1402
Tiagabine 1402
Tianeptine sodium 1403
Tiapride 1404
Tiaprofenic acid 1405
Tibezonium iodide 1406
Tibolone 1407
Ticarcillin 1407
Ticlopidine 1409
Tilidine 1410
Tilisolol hydrochloride 1411
Tiludronate disodium 1412
Timepidium bromide 1413
Timiperone 1414
Timolol 1415
Tinidazole 1417
Tioconazole 1418
Tioguanine 1419
Tiopronin 1419
Tiotropium bromide 1420
Tipranavir 1422
Tiquizium bromide 1425
Tirofiban hydrochloride 1426
Tixocortol pivalate 1428
Tizanidine 1429
Tobramycin 1429
a-Tocopherol 1431
Todralazine 1433
Tolazamide 1433
Tolbutamide 1434
Tolcapone 1434
Tolnaftate 1436
Toloxatone 1436
Tolperisone 1437
Tolterodine 1437
Tomoxetine hydrochloride 1439
Topiramate 1440
Topotecan 1441
Torasemide 1442
Toremifene 1443
Tosufloxacin 1444
Tramadol 1445
Tramazoline 1446
Trandolapril 1447
Tranexamic acid 1448
Tranilast 1449
Tranylcypromine 1450
Travoprost 1450
Trazodone 1453
Tretinoin 1453
Triamcinolone 1454
Triamcinolone acetonide 1456
Triamcinolone diacetate 1457
Triamcinolone hexacetonide 1457
Triamterene 1458
Triazolam 1459
Triclosan 1460
Trientine 1461
Trifluoperazine 1461
Trifluridine 1462
Trihexyphenidyl 1463
Trilostane 1464
Trimethoprim 1464
Trimipramine 1468
Tripelennamine 1469
Triprolidine 1469
Triptorelin 1470
Trofosfamide 1471
Tromantadine 1472
Trometamol 1472
Tropicamide 1473
Tropisetron 1473
Trospium chloride 1474
Troxerutin 1475
Troxipide 1476
L-Tryptophan 1477
Tulobuterol 1478
Tyloxapol 1478
L-Tyrosine 1479
U 1481
Ubidecarenone 1481
Undecylenic acid 1484
Unoprostone isopropyl 1484
Urapidil 1486
Urokinase 1487
Ursodeoxycholic acid 1488
V 1489
Valaciclovir 1489
Valganciclovir hydrochloride 1489
Valproic acid 1491
Valsartan 1492
Vancomycin 1494
Vardenafil hydrochloride 1495
Varenicline 1496
Vecuronium bromide 1498
Venlafaxine 1499
Verapamil 1501
Verteporfin 1502
Vigabatrin 1503
Vildagliptin 1504
Vinblastine 1505
Vincamine 1506
Vincristine 1510
Vindesine 1511
Vinorelbine 1512
Voglibose 1514
Voriconazole 1515
Vorinostat 1516
W 1517
Warfarin 1517
X 1518
Xamoterol 1518
Xantinol nicotinate 1518
Xipamide 1519
Xylometazoline 1520
Z 1521
Zafirlukast 1521
Zalcitabine 1523
Zaleplon 1525
Zanamivir 1526
Zidovudine 1528
Zileuton 1530
Ziprasidone hydrochloride 1532
Zoledronic acid 1534
Zolmitriptan 1535
Zolpidem 1537
Zonisamide 1539
Zopiclone 1540
Zotepine 1540
Index 1542
Trade Names 1542
Intermediates 1578
Enzymes, microorganisms, plants, animal tissue 1730
Substance Classes 1734
List of Abbreviations 1756

Produkt-Details

• Erscheint lt. Verlag: 14.5.2014
• Verlagsort: Stuttgart
• Sprache: englisch
• Themenwelt: Naturwissenschaften ► Chemie ► Organische Chemie
• Themenwelt: Technik
• Schlagworte: Active Pharmaceutical Ingredient • &AMP • amp;AMP • (&GT • )&GT • &LT • amp;LT • API • api compendium • api database • api guide • api reference work • Apis • approved drug • chemistry api guide • D • drug company • drug company research • drug compound • drug development • drug guide • drug index • drug manufacturers • drug synthesis • FDA approved • FDA drugs • Generic drugs • generic pharmaceutical manufacturers • generic pharmaceuticals • Generika • Intermediate • intermediates • medicinal chemistry • Medikamente • Medikamentensynthese • Medizinalchemie • Medizinische Chemie • Patente • Pharmaceutical Chemistry • pharmaceutical compound • pharmaceutical drug • pharmaceutical ingredient • pharmaceutical intermediates • pharmaceutical Patents • pharmaceutical r&d • PHARMACEUTICAL R&LT • pharmaceutical r&d • pharmaceutical research • pharmaceuticals • pharmaceutical substances • pharma r&d • PHARMA R&LT • pharma r&d • pharma reference work • pharma research • Pharmazeutika • Pharmazeutische Chemie • Pharmazeutische Wirkstoffe • Syntheseketten • synthesis of drugs • synthetic route • synthetic route drugs • trade name API
• ISBN-10: 3-13-179275-2 / 3131792752
• ISBN-13: 978-3-13-179275-4 / 9783131792754