The Reoviridae

Buch | Softcover

571 Seiten

2013 | Softcover reprint of the original 1st ed. 1983
Springer-Verlag New York Inc.
978-1-4899-0582-6 (ISBN)

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It is now just 20 years since Gomatos and his co-workers at the Rocke feller University showed that the nucleic acid in reovirus particles is double-stranded RNA (dsRNA). This discovery created great excitement, for dsRNA was at that time under intense investigation as the replicative form of viral genomes consisting of single-stranded RNA. An equally interesting and important finding followed soon after: it was found that the reovirus genome consists, not of a single nucleic acid molecule, but of 10 discrete "segments," each with its specific sequence content and each transcribed into its own messenger RNA. It is clear now that these segments are genes. Not surprisingly, the availability of a viral genome 10 unlinked genes has permitted some unique lines of in consisting of vestigation in molecular biology. Mammalian and avian reoviruses proved to be but the first of several viruses recognized as sharing Similarity in size and morphology and ge nomes consisting of 10, II, or 12 separate genes. These viruses are dis tributed throughout living organisms; among the natural hosts of mem bers of this virus family are vertebrates, Insects, and plants. Members of the Reoviridae family differ widely in the virulence that they exhibit toward their hosts . . For example, the first discovered mam malian reovirus literally is, as the name signifies, a "respiratory enteric orphan" virus, that is, a virus unassociated with disease.

1 The Members of the Family Reoviridae.- 2 The Reovirus Particle.- 3 Biochemical Aspects of Reovirus Transcription and Translation.- 4 The Reovirus Multiplication Cycle.- 5 Genetics of Reoviruses.- 6 Pathogenesis of Reovirus Infection.- 7 Orbiviruses.- 8 Rotaviruses.- 9 Cytoplasmic Polyhedrosis Viruses.- 10 The Plant Reoviridae.

Reihe/Serie	The Viruses
Zusatzinfo	XV, 571 p.
Verlagsort	New York
Sprache	englisch
Maße	155 x 235 mm
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Mikrobiologie / Infektologie / Reisemedizin
	Studium ► Querschnittsbereiche ► Infektiologie / Immunologie
	Naturwissenschaften ► Biologie ► Botanik
	Naturwissenschaften ► Biologie ► Ökologie / Naturschutz
	Naturwissenschaften ► Biologie ► Zoologie
ISBN-10	1-4899-0582-0 / 1489905820
ISBN-13	978-1-4899-0582-6 / 9781489905826
Zustand	Neuware