Comprehensive Virology

Vol. 16: Virus-Host Interactions: Viral Invasion, Persistence, and Disease

Buch | Softcover

372 Seiten

2012 | Softcover reprint of the original 1st ed. 1980
Springer-Verlag New York Inc.
978-1-4613-3131-5 (ISBN)

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The time seems ripe for a critical compendium of that segment of the biological universe we call viruses. Virology, as a science, having passed only recently through its descriptive phase of naming and num bering, has probably reached that stage at which relatively few new truly new-viruses will be discovered. Triggered by the intellectual probes and techniques of molecular biology, genetics, biochemical cytology, and high resolution microscopy and spectroscopy, the field has experienced a genuine information explosion. Few serious attempts have been made to chronicle these events. This comprehensive series, which will comprise some 6000 pages in a total of about 18 volumes, represents a commitment by a large group of active investigators to analyze, digest, and expostulate on the great mass of data relating to viruses, much of which is now amorphous and disjointed, and scattered throughout a wide literature. In this way, we hope to place the entire field in perspective, and to develop an invalua ble reference and sourcebook for researchers and students at all levels. This series is designed as a continuum that can be entered anywhere, but which also provides a logical progression of developing facts and integrated concepts.

1 Viral Invasion: Morphological, Biochemical, and Biophysical Aspects.- 1. Introduction.- 2. Methods.- 3. Invasion of Cells by Naked Viruses.- 4. Erythrocyte Membrane Structure in Relation to Viral Hemagglutination.- 5. Invasion of Cells by Enveloped Virus.- 6. Summary and Conclusion.- 7. References.- 2 Viral Persistence: Evolution of Viral Populations.- 1. Introduction.- 2. Evolution of Virus in Persistence of RNA Viruses.- 3. Evolution of Virus in Persistence of DNA Viruses.- 4. Patterns of Evolution of Virus Properties in Persistent Infection.- 5. References.- 3 Defective Interfering RNA Viruses and the Host-Cell Response.- 1. Introduction.- 2. Structure and Genome Arrangement of DI Particles.- 3. Mechanisms of DI-Particle Generation, Replication, and Interference.- 4. Role of DI Particles in Long-Term Viral Persistence.- 5. Recent Preliminary Evidence for DI-Particle Involvement in Persistence of DNA Viruses.- 6. Conclusion.- 7. References.- 4 Persistence and Transmission of Cytomegalovirus.- 1. Introduction.- 2. Physical, Morphological, and Molecular Characteristics.- 3. Detection of Cytomegalovirus Infections.- 4. Clinical Disease.- 5. Latency and Persistence.- 6. Transmission.- 7. In Vitro Transformation of Mammalian Cells.- 8. Association of Cytomegalovirus with Cancer in Humans.- 9. Vaccines and Antiviral Agents.- 10. Looking Ahead.- 11. References.- 5 Aleutian Disease of Mink: A Model for Persistent Infection.- 1. Introduction.- 2. The Virus.- 3. The Disease Process.- 4. Immunological Aspects of Infection.- 5. Genetic Aspects.- 6. Discussion.- 7. References.- 6 Role of Viruses in Chronic Neurological Diseases.- 1. Introduction.- 2. Mechanisms of Virus Dissemination to the CNS.- 3. Mechanisms of Viral Clearance from the CNS.- 4. Mechanisms of Chronic Disease Induction.- 5. Subacute Spongiform Encephalopathies.- 6. Human Disease of Suspected Viral Etiology.- 7. Conclusions.- 8. References.- 7 Host Plant Responses to Virus Infection.- 1. Introduction.- 2. Kinds of Host Response.- 3. Influence of Host Genotype.- 4. Influence of the Viral Genome.- 5. Possible Mechanisms of Disease Induction.- 6. Organelle Responses.- 7. Cellular Responses.- 8. Plant Responses.- 9. Use of Protoplasts to Study Host Responses.- 10. References.

Reihe/Serie	Comprehensive Virology ; 16
Zusatzinfo	XVI, 372 p.
Verlagsort	New York, NY
Sprache	englisch
Maße	170 x 244 mm
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Mikrobiologie / Infektologie / Reisemedizin
	Studium ► Querschnittsbereiche ► Infektiologie / Immunologie
	Naturwissenschaften ► Biologie ► Mikrobiologie / Immunologie
ISBN-10	1-4613-3131-5 / 1461331315
ISBN-13	978-1-4613-3131-5 / 9781461331315
Zustand	Neuware