Anion Carriers of Mitochondrial Membranes
Springer Berlin (Verlag)
978-3-642-74541-6 (ISBN)
I. Isolation and Reconstitution of Carriers.- Purification and Characterization of Three Mitochondrial Substrate Carriers: the Phosphate, the 2-Oxoglutarate and the Dicarboxylate Carriers.- Purification and Reconstitution of the 2-Oxoglutarate Carrier from Bovine Heart and Liver Mitochondria.- Hydroxyapatite Chromatography as a Tool for the Isolation of Anion Carriers and Other Membrane Proteins.- Purification of the Monocarboxylate Carrier by Affinity Chromatography.- Recent Developments in the Extraction, Reconstitution, and Purification of the Mitochondrial Citrate Transporter from Normal and Diabetic Rats.- Isolation and Functional Reconstitution of the Dicarboxylate Carrier from Bovine Liver Mitochondria.- New Photoaffinity Derivatives of Malonate and Succinate to Study Mitochondrial Carrier Systems.- Reaction Mechanism of the Reconstituted Aspartate/Glutamate Antiporter from Mitochondria. Reversible Switching to Uniport function.- II. Functional Evidence and Characterization of Various Carriers.- Recent Studies on the Mitochondrial Phosphate Transport Protein (PTP) and on its Relationship to the ADP/ATP Translocase (AAC) and the Uncoupling Protein (UCP).- Mitochondrial Phosphate Carrier: Relation of its SH Groups to Oligomeric Organization.- Recent Developments in the Study of the Conformational States and the Nucleotide Binding Sites of the ADP/ATP Carrier.- Immunological and Enzymatic Approaches to the Orientation of the Membrane Bound ADP/ATP Carrier.- The ATP/ADP Antiporter is Involved in the Uncoupling Effect of Fatty Acids.- Molecular Aspects of the Adenine Nucleotide Carrier from Mitochondria.- Kinetic Mechanisms of the Adenylic and the Oxoglutaric Carriers: A Comparison.- III. Porins.- Porins from Mitochondrial and Bacterial Outer Membrances: Structural and Functional Aspects.- Modulation of the Mitochondrial Channel VDAC by a Variety of Agents.- Bioenergetic Consequences of the Lack of Mitochondrial Porin: Identification of a Putative New Pore.- Purification of Mammalian Porins.- IV. Uncoupling Protein of Brown Adipose Tissue.- A Molecular Biology Study of the Uncoupling Protein of Brown Fat Mitochondria. A Contribution to the Analysis of Genes of Mitochondrial Carriers.- On the Mechanism of Transport by the Uncoupling Protein from Brown Adipose Tissue Mitochondria.- Regulation of the Amount and Activity of the Uncoupling Protein Thermogenin in Brown Adipose Tissue.- Regulation of Uncoupling Protein and Formation of Thermogenic Mitochondria.- V. Carriers and their Cellular Environment.- Biogenesis of Mitochondrial Proteins.- Insensitivity of Carbamoyl-Phosphate Synthetase Towards Inhibition by Carbamoyl Phosphate Makes it Unlikely that Mitochondrial Metabolite Transport Controls Ornithine Cycle Flux.- Mitochondrial Adenine Nucleotide Translocation During Fatty Acid Metabolism in the Intact Cell.- Control of Oxidative Phosphorylation in Yeast Mitochondria: The Role of Phosphate Carrier and pH.- The Role of Pyrophosphate and the Adenine Nucleotide Transporter in the Regulation of the Intra-Mitochondrial Volume.- Role of the Mitochondrial Outer Membrane in Dynamic Compartmentation of Adenine Nucleotides.- Topology of Peripheral Kinases: its Importance in Transmission of Mitochondrial Energy.- Control of Mitochondrial Energy Production in vivo.
| Erscheint lt. Verlag | 22.11.2011 |
|---|---|
| Zusatzinfo | XI, 381 p. |
| Verlagsort | Berlin |
| Sprache | englisch |
| Maße | 170 x 244 mm |
| Gewicht | 680 g |
| Themenwelt | Naturwissenschaften ► Biologie ► Biochemie |
| Naturwissenschaften ► Biologie ► Zellbiologie | |
| Schlagworte | Aspartat • ATP • Biology • Cell • Glutamat • Membrane • Metabolism • mitochondria • Molecular Biology • Nucleotide • phosphorylation • Protein • Regulation • tissue • Topology |
| ISBN-10 | 3-642-74541-5 / 3642745415 |
| ISBN-13 | 978-3-642-74541-6 / 9783642745416 |
| Zustand | Neuware |
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