Towards Efficient Designing of Safe Nanomaterials

Innovative Merge of Computational Approaches and Experimental Techniques

Jerzy Leszczynski, Tomasz Puzyn (Herausgeber)

Buch | Hardcover

378 Seiten

2012
Royal Society of Chemistry (Verlag)
978-1-84973-453-0 (ISBN)

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The expanding field of nanotechnology is now one of the most promising areas of science. However, because some nanoparticles can have a negative impact on human health and the environment, the design of novel materials must always be accompanied by a comprehensive risk assessment. Until now, the information on the methods available has been fragmented and incomplete. This book is the first to provide a comprehensive review of recent progress and challenges in the risk assessment of nanomaterials by empirical and computational techniques. Topics covered include: benefits versus risks, carbon based nanomaterials, environmental detection and quantitative analysis, chemometric modelling, human exposure assessment, toxicity testing, nano-QSAR, risk assessment strategies, policy and regulatory frameworks.

Jerzy Leszczynski is Professor of Chemistry and a President's Distinguished Fellow. Director of Interdisciplinary Nanotoxicity Center. Author and co-author of almost 700 peer-reviewed papers (H index 47) and 50 book chapters.

Nanomaterials: benefits and risks;

Experimental characterizing structural properties of nanoparticles related to their toxicity;

Structure-property mapping methods;

Modelling properties of nanoparticles based on quantum-mechanical methods;

Ontology;

Empirical determination of nanoparticles' behavior in environmental media;

Computational mass-ballance modeling of environmental transport and fate of engineered nanoparticles;

Pharmacokinetics and biological fate of nanoparticles;

Pharmacokinetic-based modeling;

Modeling kinetics of nanoparticle cellular interaction and transport;

Toxicity and Ecotoxicity testing of engineered nanoparticles - experimental point of view;

In vitro toxicity of nanomaterials;

In vivo testing;

Computational modeling of interactions between nanoparticles and other species;

Comprehensive Environmental Assessment as a Tool for Nanomaterial Risk Assessment;

Predicting oxidative stress;

Nano-QSAR

Erscheint lt. Verlag	27.9.2012
Reihe/Serie	Nanoscience & Nanotechnology Series ; Volume 25
Verlagsort	Cambridge
Sprache	englisch
Maße	156 x 234 mm
Gewicht	748 g
Themenwelt	Naturwissenschaften ► Chemie
Themenwelt	Technik ► Maschinenbau
ISBN-10	1-84973-453-4 / 1849734534
ISBN-13	978-1-84973-453-0 / 9781849734530
Zustand	Neuware