Cell-Extracellular Matrix Interactions in Cancer
Seiten
2009
|
2010 ed.
Springer-Verlag New York Inc.
978-1-4419-0813-1 (ISBN)
Springer-Verlag New York Inc.
978-1-4419-0813-1 (ISBN)
Cancer was thought to originate from alterations in intercellular signaling that resulted in the transformation of cells, their uncontrolled proliferation and metastasis. Cells adhere and receive signals from various extracellular matrices via transmembrane receptors, the best known of which are the heterodimeric glycoproteins, integrins.
Cancer was thought to originate from alterations in intercellular signaling that resulted in the transformation of cells, their uncontrolled proliferation and metastasis. There is now an increasing body of evidence demonstrating that the surrounding matrix and cell-matrix interactions are also major players in this process. Cells adhere and receive signals from various extracellular matrices via transmembrane receptors, the best known of which are the heterodimeric glycoproteins, integrins.
Cancer was thought to originate from alterations in intercellular signaling that resulted in the transformation of cells, their uncontrolled proliferation and metastasis. There is now an increasing body of evidence demonstrating that the surrounding matrix and cell-matrix interactions are also major players in this process. Cells adhere and receive signals from various extracellular matrices via transmembrane receptors, the best known of which are the heterodimeric glycoproteins, integrins.
The Extracellular Matrix: An Overview.- Integrin Structure and Function.- Cancer in Context: Importance of the Tumor Microenvironment.- Basement Membrane Collagens and Cancer.- Laminins and Cancer Progression.- Fibronectins and Their Receptors in Cancer.- Vitronectin-Binding Integrins in Cancer.- The Function of SPARC in Tumor Cell Biology: SPARC as a Modulator of Cell–Extracellular Matrix Interaction.- Proteoglycans and Cancer.- Tetraspanins in Cancer.- The Role of Integrin-Linked Kinase in Cancer Development and Progression.- Focal Adhesion Kinase with the Interacting Proteins and Signaling in Cancer.
| Erscheint lt. Verlag | 14.12.2009 |
|---|---|
| Zusatzinfo | XII, 314 p. With 1 4-page color insert. |
| Verlagsort | New York, NY |
| Sprache | englisch |
| Maße | 155 x 235 mm |
| Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie |
| Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie | |
| Medizin / Pharmazie ► Studium | |
| Naturwissenschaften ► Biologie ► Zellbiologie | |
| Schlagworte | Extrazelluläre Matrix • Krebs (Krankheit) |
| ISBN-10 | 1-4419-0813-7 / 1441908137 |
| ISBN-13 | 978-1-4419-0813-1 / 9781441908131 |
| Zustand | Neuware |
| Haben Sie eine Frage zum Produkt? |
Mehr entdecken
aus dem Bereich
aus dem Bereich
Korrigierter Nachdruck 2020 mit allen Ergänzungen der UICC aus den …
Buch | Softcover (2020)
Wiley-VCH (Verlag)
CHF 59,95
Resilienz innovativ stärken : ein Praxishandbuch
Buch | Softcover (2023)
Kohlhammer (Verlag)
CHF 49,95
