Pancreatic Cancer
Springer-Verlag New York Inc.
978-0-387-77497-8 (ISBN)
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This handbook details advances in pancreatic cancer research that have a profound and lasting impact on the field. It features the work of authors who are the very best in their respective fields and will have widespread appeal among clinicians, pathologists and basic scientists who are now struggling to understand this complex and rapidly expanding field.
John Neoptolemos is Professor of Surgery and Head of the Division of Surgery and Oncology at the University of Liverpool and Honorary Consultant Surgeon at the Royal Liverpool University Hospital. As an undergraduate he studied Natural Sciences at Cambridge (BA 1973, MA 1976) before completing his clinical undergraduate training at Guys Hospital (Cambridge: MB, BChir 1976). He completed his academic and clinical training in Leicester under Prof. Sir Peter Bell, being awarded a Doctorate in Medicine in 1986. Raul A. Urrutia, M.D., Mayo Clinic College of Medicine, Rochester, MN USA. Dr. Urrutia was awarded his M.D., Magna Cum Laude, by the University of Cordoba, Argentina. Dr. James L. Abbruzzese is the Chairman of the Department of Gastrointestinal Medical Oncology at the University of Texas M. D. Anderson Cancer Center, Houston, Texas, where he holds the Annie Laurie Howard Research Distinguished Professorship. Author of over 150 original articles and book chapters, Dr. Abbruzzese has recently been appointed the Editor-in-Chief of the International Journal of Pancreatology. He serves on the editorial board of a number of prestigious journals, including the Journal of Clinical Oncology and Clinical Cancer Research, and also serves on the Scientific Advisory Board of the Lustgarten Foundation for Pancreatic Cancer Research. Markus W. Büchler is Professor of Surgery at the University of Heidelberg, Germany. He studied medicine at the Universities of Heidelberg and Berlin and was trained in surgery at the Department of Surgery, University of Ulm, where he was appointed a Consultant Surgeon in 1987 and Vice Chairman in 1991. Professor Büchler is a specialist in hepato-pancreato-biliary surgery (HPB) and, in particular, pancreatic surgery. He has a substantial curriculum of scientific publications in the field of HPB diseases, especially in translational research of pancreatic cancer. He is Editor or Editorial Board member of many leading journals in general and gastrointestinal surgery, translational and molecular research in pancreatology and other gastrointestinal diseases, including Annals of Surgery, British Journal of Surgery. Digestive Surgery (Editor), Pancreas, Langenbeck's Archive of Surgery (Editor), HPB, and Surgery.
Section One: The Nature of Pancreatic Cancer
Epidemiology: world overview, risk factors, prospects for prevention
Development and structure of pancreas
Pathologic classification and biological behaviour of pancreatic neoplasia
Developmental molecular biology of the pancreas
Molecular pathology of precursor lesions of pancreatic cancer, pancreatic intraepithelial neoplasia (PanIN), intraductal papillary mucinous neoplasm (IPMN), and mucinous cystic neoplasm (MCN)
Epigenetics: its fundamentals and applications to a revised comprehensive progression model for pancreatic cancer
Molecular pathology of pancreatic neuroendocrine tumours MEN-1: gastrinomas, insulinoma, Non-Functioning Tumours, VIPoma, glucagonoma, Von Hippel-Lindau, Neurofibromatosis
Sporadic neuroendocrine pancreatic tumours
Molecular pathology of non-pancreatic cancer lesions: Ampullary cancer, intra-pancreatic bile duct cancer, and duodenal cancer
Miscellaneous non-pancreatic non-endocrine tumours
Novel molecular relationships between chronic pancreatitis and cancer
Pancreatic cancer stem cells
Cell cycle control: signalling pathways in pancreatic pathogenesis
Apoptosis: signalling pathways in pancreatic pathogenesis
EGFR: signalling pathways in pancreatic pathogenesis Pl3, Akt, lKK, Ras, Raf, MAPKK, ERK
Hedgehog: signalling pathways in pancreatic pathogenesis
Smad4/TGF-ß pathway: signalling pathways in pancreatic pathogenesis
Notch signalling in pancreatic morphogenesis and pancreatic cancer
Molecular characterization of pancreatic cell lines
Mouse models of exocrine pancreatic cancer
Principles and applications of microarray gene expression in pancreatic cancer
Principles and applications of proteomics in pancreatic cancer
Tumour-stromal interaction: invasion and metastases
Genetic susceptibility, high risk groups, chronic and hereditary pancreatitis, familial pancreatic cancer syndromes
Inherited endocrine pancreatic tumors associated with Multiple Endocrine Neoplasia Type 1 Von-Hippel-Lindau Syndrome, and Neurofibromatosis Type 1
Section Two: Clinical Management of Pancreatic Cancer
Clinical decision making in pancreatic cancer
Paraneoplastic syndromes
Diagnostic and therapeutic response markers
CT and fusion PET-CT Diagnosis, staging, and follow-up
MRI and MRCP: diagnosis and staging of pancreatic cancer
EUS Diagnosis and staging
Laparoscopy and laparoscopic ultrasound: diagnosis and staging
Overview of palliative management for pancreatic cancer
Endoscopy.
Interventional radiology
Role of palliative surgery in advanced pancreatic cancer
Chemotherapy for advanced pancreatic cancer
Developments in chemoradiation in advanced pancreatic cancer
Surgical resection for pancreatic cancer
Role of venous resection in pancreatic cancer surgery
Pathological reporting and staging following resection
Japanese Pancreas Society staging for pancreatic cancer
Adjuvant chemotherapy in pancreatic cancer
Case for adjuvant chemoradiation therapy for pancreatic cancer
Case for neoadjuvant treatment in pancreatic cancer
Borderline resectable disease
Management of cystic neoplasms serous cystic neoplasms mucinous, cystic neoplasms, intraductal paillary mucinous neoplasms
Laparoscopic surgery for pancreatic neoplasm
Modern Japanese approach to pancreas cancer
Section Three: New Directions
Development of novel biomarkers
Inherited genetics of pancreatic cancer and secondary screening
Gene therapy for pancreatic cancer
Vaccine therapy and immunotherapy
Emerging targets in pancreatic cancer
| Erscheint lt. Verlag | 22.1.2010 |
|---|---|
| Reihe/Serie | Handbook of Pancreatic Cancer | 1.20 |
| Zusatzinfo | LVIII, 1390 p. In 2 volumes, not available separately. |
| Verlagsort | New York, NY |
| Sprache | englisch |
| Maße | 155 x 235 mm |
| Themenwelt | Medizinische Fachgebiete ► Innere Medizin ► Endokrinologie |
| Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie | |
| Medizin / Pharmazie ► Studium | |
| ISBN-10 | 0-387-77497-1 / 0387774971 |
| ISBN-13 | 978-0-387-77497-8 / 9780387774978 |
| Zustand | Neuware |
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