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The Megaloblastic Anaemias

(Autor)

Buch | Hardcover
224 Seiten
1990 | 3rd Revised edition
Blackwell Science Ltd (Verlag)
978-0-632-02549-7 (ISBN)
CHF 95,15 inkl. MwSt
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A reference work which gives account of the physiology and pathophysiology of vitamin B12 (cobalamin) and folate and their biochemical roles in health and disease. Clinical presentation of patients with megaloblastic anaemias and the assessment of the deficiency state is described.
Megaloblastic anaemia is a common disorder encountered in daily haematological practice. The possibility of such diagnosis needs to be considered with every blood count showing an increase in red cell size. The clinical importance of megaloblastic anaemia is that it is commonly due to a deficiency of either folate or cobalamin (vitamin B12). Therapy with the appropriate vitamin produces very gratifying clinical benefits. Although a clinical suspicion of megaloblastic anaemia may initiate appropriate investigations, diagnosis must be made in the laboratory from examination of the blood and marrow. The book has been considerably shortened for the new edition, nevertheless is a full account of the field for the practising haematologist and for the student specialising in haematology.

Clinical presentation in megaloblastic anaemia; Normal cobalamin metabolism; Assessment of cobalamin status; Normal folate metabolism; Assesment of folate status; The response to therapy in megaloblastic anaemia; Biochemical basis of megaloblastic anaemia; Investigation, management and treatment in megaloblastic anaemia; Pernicious anaemia; Megaloblastic anaemia after gastric surgery; Nutritional cobalamin deficiency; Disease of the small gut; Inherited disorders of cobalamin and folate metabolism and disorders presenting in early life; Raised serum cobalamin levels; Nutritional folate deficiency; Folate deficiency in pregnancy; Folate and alcohol; Folate and anticonvulsant drugs; Chronic myelofibrosis and other myeloproliferative disorders; Chronic haemolytic states; Odds and ends

Erscheint lt. Verlag 6.3.1990
Zusatzinfo 65
Verlagsort Oxford
Sprache englisch
Maße 172 x 244 mm
Gewicht 623 g
Themenwelt Medizinische Fachgebiete Innere Medizin Hämatologie
ISBN-10 0-632-02549-2 / 0632025492
ISBN-13 978-0-632-02549-7 / 9780632025497
Zustand Neuware
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