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Skin Cancer and UV Radiation -

Skin Cancer and UV Radiation

Buch | Softcover
XLII, 1334 Seiten
1998 | Softcover reprint of the original 1st ed. 1997
Springer Berlin (Verlag)
978-3-642-64547-1 (ISBN)
CHF 119,75 inkl. MwSt
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UV radiation is recognized as the major risk factor for skin can cer. For the last three decades the incidence and mortality of skin cancer have been increasing steadily in almost all parts of the world. Unfortunately, there have been very few advances in the management and treatment of skin cancer. In comparison to other malignant tumors, skin cancer offers the unique opportuni ty to identify this tumor at an early stage. Thus, there is strong interest in preventing death by early diagnosis and prompt treat ment. The proceedings of the International Congress on Skin Cancer and UV Radiation which was held in Bochum Germany in October 1996, reflect the newest scientific standards in the field of skin cancer. The conference in Bochum was a platform for leading scientists from all over the world to discuss the complexity and diversity of UV radiation in its interaction with the skin. Starting with basic science like physiology, immunology, and molecular biochemistry of the skin as influenced by UV radiati on, the book presents a profound survey into the field of skin can cer by focusing on the latest scientific results in prevention, early detection, treatment, and epidemiology. The congress in Bochum in 1996 was organized to provide a starting point for coordinated European strategies against skin cancer with internationally renown scientists.

Skin Cancer and UV Radiation in History of Medicine.- Sun and Men: An Ambivalent Relationship in the History of Medicine.- History of Therapeutic UV Radiation.- History of Skin Cancer.- UV Radiation and the Environment.- Basic Physical Aspects of Environmental UV Radiation.- UV Prognosis and UV Index Services in Europe.- Ozone Holes and UV Radiation: Ecological Consequences for Plants.- Public On-Line Information on Solar UV Irradiance Based on Spectrometric Measurements in a Sea Resort.- UV-Expert: A Spectroradiometric System for Individual UV Dosimetry.- Effects of UV Radiation on Human Skin.- MolecularBasics.- Basic Aspects of Collagen Metabolism.- Sunburn and Apoptosis.- Dermal Elimination of Apoptotic and Vital Melanocytes After UVA1 Radiation.- Importance of Calcium-Magnesium Antagonism and Thiols for Diminution of UVA1-Induced Cell Damage.- Molecular Role of Reactive Oxygen Species in Photoaging and Tumor Progression.- How Much Sun Do We Need To Produce Vitamin D?.- UV Radiation and Urocanic Acid.- Activation of Human Endogenous Retroviral Sequences by UVB.- Melanins,Pigmentation and Erythema.- Melanins and Related Metabolites in Skin Photoprotection.- Physiology of Skin Pigmentation: Recent Results.- Time Course of UV Erythema.- Measurement of Constitutive Skin Phototypes.- Photoprotection by Total Melanin Content and Pigment Phenotype (Eumelanin, Pheomelanin) in Human Melanoma Cell Lines.- Melatonin: Multiple Functions in Signaling and Protection.- Principles of Phototesting and Photopatch Testing.- Optics of Human Skin: UV Effects Investigated with Dye Lasers.- Quantitative Evaluation of the UV Reaction at 325 nm with a Two-Dimensional Laser Doppler Perfusion Imager.- Immunology.- UV Radiation and Cytokines.- Effect of UV Light on the Production of Proopiomelanocortin-Derived Peptides and Melanocortin Receptors in the Skin.- Cytokines, Cytokine Receptors and Cytokine Antibodies: Clinical Implications.- Mexoryl SX Protects Against Photoimmunosuppression.- UV Protection: Sunscreens and other UV Protective Measures.- The Evolution of Recent Sunscreen.- Sunscreens in Europe: Recent Developments.- UV Protection by Sunscreens.- Photostable Suncare Products: Major Progress in Sun Protection.- Evaluation of Sunscreens.- Regulations on Sunscreens.- Use and Misuse of Sunscreens.- Sunscreens in Melanoma Protection - Pros and Cons.- Influence of Sunscreen on the Spectral Energy Distribution of Ultraviolet Radiation in Human Skin.- Clothing as Protection Against the Sun.- Developing a United States Sun-Protective Clothing Standard.- New UV Absorbers for Sun Protective Fabrics.- Novel Approaches to Photoprotection.- Betacarotene in the Prevention of Chronic Ultraviolet Damage and Non-melanoma Skin Cancer.- Therapeutic Use of UV Radiation.- Balneophototherapy.- A New Psoralen-Containing Gel for Topical PUVA Therapy: Development and Treatment Results with Palmoplantar and Plaque-Type Psoriasis, Pustulosis Palmaris et Plantaria and Chronic/Hyperkeratotic Eczema.- PUVA, Psoralens and Skin Cancer.- PUVA Bath Therapy: A Therapeutic Alternative to Systemic Photochemotherapy.- Artifical Light Sources for Phototherapy.- Trioxsalen Bath PUVA Does Not Increase the Risk of Squamous Cell Skin Carcinoma: A Joint Analysis of 1124 Swedish and Finnish Patients Followed Up for 10 Years.- Photoaging and Other Side Effects Due to the Long-Term PUVA Therapy.- Evaluation of PUVA Bath Therapy for Sclerosing Dermatoses by in Vivo Measurement of Skin Elasticity Using Cutometer SEM 575.- Kinetics of 8-Methoxypsoralen - Induced Skin Photosensitization in PUVA Bath Photochemotherapy.- 8-Methoxypsoralen Plasma Levels in Patients with Different Dermatoses Following PUVA Bath Photochemotherapy.- A New Treatment Modality of Localized Scleroderma: Low-Dose UVAl Phototherapy.- Influences of UV Radiation in the Therapy of Psoriasis Vulgaris.- Assessment of Actinic Elastosis by 20 MHz Sonography.- Photopheresis as a Therapeutical Alternative for PUVA.- Extracorporeal Photochemotherapy in the Treatment of Cutaneous T Cell Lymphoma.- Modifications in Cutaneous Infiltrate and Death Rate of Lymphoid Cells in Mycosis Fungoides Patients Treated with Photopheresis.- Epidemiology of Skin Cancer.- Future Trends in the Incidence of Cutaneous Malignant Melanoma in White Populations.- Recent Epidemiological Trends of Cutaneous Melanoma in Germany, Austria and Switzerland.Results of the Central Malignant Melanoma Registry.- Seasonal Patterns in the Diagnosis of Cutaneous Malignant Melanoma due to Differential Detection Rather than Biological Causes. An Analysis of the Data of the German Central Malignant Melanoma Registry.- Parametric Estimation of the ”Risk of Melanoma-Related Death“ with the Recursion Formula of the Gompertz Survival Function.- Nonmelanoma Skin Cancer Mortality.- Basal and Squamous Cell Carcinoma: Sex, Age and Location Distribution.- Meta-analysis of the Role of Oral Contraceptives in the Development of Malignant Melanoma Based on Published Case-Control Studies Revealed no Evidence for an Association.- Demographic and Enviromental Factors Associated with Excess Risk for Malignant Melanoma and Non-melanocytic Skin Cancers in Alberta, Canada.- Risk Factors of Skin Cancer.- Defining Individual Risk Factors for Skin Melanoma.- Pregnancy, Nevi, and Melanoma.- Allelic Loss and Skin Cancer.- Cancer Prone Genophotodermatoses.- Nevi and Initiation by Sun.- Children and Sun.- Skin Cancer Risks from Ultraviolet Lamps and Sunbeds.- Artificial Light Sources and Skin Cancer: Definition of a Carcinogenic Action Spectrum.- Efficiency of Therapeutic UV Devices and the Risk of Skin Cancer.- Occupation and Skin Cancer.- Skin Cancers in Organ Transplant Recipients.- Malignant and Virus-Induced Skin Tumors in a 49-Year-Old Patient with a Heart Transplant.- HIV Infection and Malignancies.- Thermal Injury and UV Radiation as Cofactors in Scar-Associated Malignant Melanoma: Case Report and Review of the Literature.- Naevi and Solar Keratoses as Risk Factors for Melanoma in Australia.- Molecular Basics of Skin Cancer.- Immunology of Melanoma.- The Genetics of Actinic Keratoses.- Multiple p53 Mutations are Common in Basal Cell Carcinoma.- Nuclear Reactivity Relationship Among p53 and Some of its Downstream Proteins is Predictive of p53 Functional State.- DNA Photodamage and its Repair in Human Epidermis in Vivo.- UVB Irradiation, Mismatch Repair and Cutaneous Melanoma.- Human Photoimmunology: The Relevance of Ultraviolet Radiation-Induced Immunosuppression for Photocarcinogenesis.- The Induction of Nevi and Skin Tumors in Pigmented Hairless Mice HRA, HRII-c/+SKH by 9,10 Dimethyl-1,2-Benzanthracene and UV Radiation.- The Role of Human Papillomaviruses in Non-melanoma Skin Cancer.- Presence of HPV DNA in Trichilemmomas Detected by Polymerase Chain Reaction.- Immunhistology of Skin Cancer.- Biochemical Cell Markers Used in Diagnosis of Spinous Cellular Carcinoma of the Lower Lip.- Immunohistochemical Evaluation of Cell Cycle Regulating Proteins in Epithelial Skin Tumors.- Screening Campaigns and Prevention of Skin Cancer.- Skin Cancer Prevention.- Do Not Give Skin Cancer A Chance.- Worldwide Experience with the Realization of Educational Campaignes.- Legislation of Skin Cancer Prevention in Europe.- European Screening Projects: Experience in Germany.- Skin Cancer Prevention in Germany.- The Activities of German Cancer Aid for the Prevention and Early Detection of Skin Cancer.- Skin Cancer Prevention in North Rhine-Westphalia: How to Place the Message.- Health and Fun: A Program for Preventive Care in Primary Schools.- Primary prevention of Skin Cancer: A Model Conception in Cooperation with Schools and Kindergartens.- Cost Effectiveness in Skin Cancers Prevention.- Public Health Potential for Cancer Prevention in Europe.- The Knowledge about Melanoma Risk Factors in the Public: Has it Changed for the Better?.- Preventive Suggestions to Avoid Excessive Sunlight Exposure.- The Improvement of Sun Protection Among Children: Empirical Evidence from Successive Studies in Gottingen.- Multimedia Techniques in the Primary and Secondary Prevention of Malignant Melanoma.- Statistical Methods for Evaluating the Efficacy of Screening Programs for Skin Cancer.- Quality Assurance in Cancer Screening.- General Guidelines for Quality Assurance of Skin Cancer Screening.- Diagnosis of Skin Cancer.- Pitfalls in the Diagnosis of Pigmented Skin Tumors.- Epiluminescence Microscopy: Diagnostic Standard.- Differential Diagnosis of Skin Tumors Using Tumor Microcirculation.- High-Frequency Ultrasound of Skin Tumors.- High-Frequency Ultrasound (50-150 MHz) in Dermatology.- Computerised Diagnosis of Skin Cancer Using Neural Networks.- Automated Instrumentation for the Diagnosis of Invasive Melanoma: Image Analysis of Oil Epiluminescence Microscopy.- Noninvasive Bioengineering Techniques to Measure UV Effects in Human Skin.- Influence of Two Minimal Erythema Doses on the Dermoscopic Image of Acquired Melanocytic Nevi.- Instrumental Evaluation of Skin Colour and Melanoma Risk.- Nevocellular Nevus, Malignant Melanoma, Basal Cell Carcinoma and Seborrheic Keratosis Can Be Differentiated Using Magnetic Resonance Microscopy.- Skin Cancer Evaluation using Texture and Form Analysis of Sonograms.- The Pre-operative Lympho-scintigraphy: Drainage Pathways and Variability in the Malignant Melanoma of the Trunc.- Positron Emission Tomography: Evaluation of the Diagnostic Validity in Metastatic Melanoma.- Tyrosinase Fails as an Early Melanoma Progression Marker.- Evaluation of Serum Protein S-100 as a New Melanoma Marker.- Single Dimensional Line Measurement with a Laser Sensor by Dynamic Focusing Principle as a Tool of Modern Skin Physiology.- Telecommunication of Digitized Dermatoscopic Images Improves Histopathological Examination and Surgical Treatment of Skin Lesions.- Skin Cancer Therapy.- Recent Developments in Melanoma Surgery.- Surgical Treatment of Non-Melanoma Skin Cancer.- New Aspects in the Chemotherapy of Malignant Melanoma.- The Sentinel Lymphono dec tomy in the Treatment of Malignant Melanomas.- Advances in the Adjuvant Therapy of Melanoma.- Adjuvant Therapy for Malignant Melanoma.- Active Immunotherapy in Melanoma Patients: New Experiences at National Cancer Institute of Milan.- New Developments in (Chemo)Immunotherapy in the Management of Micrometastatic and Macrometastatic Melanoma.- Follow-Up of Malignant Skin Tumors.- Vaccination Against the Mouse B16 Melanoma: Irradiated Tumor Cells Mixed with Liposome Encapsulated IL-2 as an Alternative to IL-2-Gene Transfected Tumor Cells.- Fotemustine Monochemotherapy in Patients with Advanced Melanoma.- Quality of Life and Pain Management of Terminal III Melanoma Patients: A Retrospective Study.- Retinoids and Photocarcinogenesis: An End to the Controversy?.- The Short-Term Use of 5-Fluorouracil to Identify Subclinical Actinic Keratoses in Young Adults with Subsequent Long-Term Application of Tretinoin to Prevent Tumor Progression.- Improvement of the Therapy of Actinic Keratoses with 5-Fluorouracil: Clinical Results of a Treatment with a Low Dose Patch.- Photodynamic Therapy of Skin Cancers: A New Therapeutic Alternative?.- The Application of Nd-Yag Laser in the Surgical Treatment of Skin Cancer.- Case Reports.- Desmoplastic Malignant Melanoma: Case Report.- Amelanotic Malignant Melanoma: Case Report.- An Unusual Case of Dermatofibrosarcoma Protuberans.- Mistletoe Treatment for Melanoma Brain Metastases: A Single Case.

Erscheinungsdatum
Mitarbeit Assistent: H.P. Schwarze, M. Freitag
Vorwort O. Braun-Falco, A. Horstmann
Zusatzinfo XLII, 1334 p. 402 illus., 136 illus. in color.
Verlagsort Berlin
Sprache englisch
Maße 155 x 235 mm
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Dermatologie
Medizin / Pharmazie Medizinische Fachgebiete Onkologie
Schlagworte Cancer • Cancer Therapy • Dermatology • Diagnostics • epidemiology • immunotherapy • Laser • melanoma • Molecular Biology • prevention • Screening • Skin • skin cancer • therapy • UV radiation
ISBN-10 3-642-64547-X / 364264547X
ISBN-13 978-3-642-64547-1 / 9783642645471
Zustand Neuware
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