Practical Radiobiology for Proton Therapy Planning (eBook)

Bleddyn Jones (Autor)

eBook Download: EPUB

2017
Institute of Physics Publishing (Verlag)
978-0-7503-1338-4 (ISBN)

Infos

This book covers the principles, advantages
and potential pitfalls that occur in proton therapy, especially its
radiobiological modelling applications. It is intended to educate, inform and stimulate
further research questions by blending the relevant physics, biology and
medical aspects of this multidisciplinary subject.

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Practical
Radiobiology for Proton Therapy Planning covers the
principles, advantages and potential pitfalls that occur in proton therapy,
especially its radiobiological modelling applications. This book is intended to
educate, inform and to stimulate further research questions. Additionally, it
will help proton therapy centres when designing new treatments or when
unintended errors or delays occur. The clear descriptions of useful equations
for high LET particle beam applications, worked examples of many important
clinical situations, and discussion of how proton therapy may be optimized are
all important features of the text. This important book blends the relevant
physics, biology and medical aspects of this multidisciplinary subject.

Autor

Bleddyn Jones is Professor of Clinical Radiation Biology at the new Gray Institute for Radiation Oncology and Biology at the University of Oxford, as well as Honorary Consultant in Clinical Oncology, Oxford Radcliffe Hospitals NHS Trust. Over the past 20 years he has been involved with selection and referral of patients abroad for particle therapy. Present research interests include development of new accelerator technology, better prediction of the biological effects of different qualities of radiation and the role of fractionation in particle beam therapy. He is Deputy Director of the Oxford Master of Science course in Radiation Biology and Co-Director of the new Particle Therapy Cancer Research Institute. 

Inhalt

Preface
1. Particle physics for biological interactions

2. The essential radiobiology background

3. Some important medical and surgical
considerations, including clinical trials

4. Treatment planning and further medical perspectives

5. Historical development of radiotherapy
including what was learned from fast neutrons

6. Fractionation

7. The case for using a variable proton RBE

8. A general RBE simple efficiency model
for protons and light ions

9. 
Inclusion of the energy-efficiency LET and RBE model in proton therapy

10. Compensating for elapsed time:
unintended treatment interruptions & re-treatments

11. Errors of Bragg
Peak Positioning and their radiobiological correction

12. Additional considerations and conclusions

Produkt-Details

• Erscheint lt. Verlag: 19.12.2017
• Reihe/Serie: IOP Expanding Physics
• Reihe/Serie: IPEM-IOP Series in Physics and Engineering in Medicine and Biology
• Reihe/Serie: IPEM-IOP Series in Physics and Engineering in Medicine and Biology
• Reihe/Serie: IPEM-IOP Series in Physics and Engineering in Medicine and Biology
• Reihe/Serie: ISSN
• Reihe/Serie: ISSN
• Zusatzinfo: With figures in colour and black and white
• Verlagsort: Bristol
• Sprache: englisch
• Themenwelt: Medizin / Pharmazie
• ISBN-10: 0-7503-1338-2 / 0750313382
• ISBN-13: 978-0-7503-1338-4 / 9780750313384