STAT Inhibitors in Cancer

Buch | Softcover

VII, 195 Seiten

2018 | 1. Softcover reprint of the original 1st ed. 2016
Springer International Publishing (Verlag)
978-3-319-82701-8 (ISBN)

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This volume, which includes contributions from leading scientists and clinicians in the field, provides definitive, state-of-the-art information on STAT inhibitors in a biological and clinical context. It gives an overview of the biology of the STAT family of transcription factors and their role in cancer etiology. Additionally, it describes the raft of therapeutic approaches being used to inhibit STATs in the context of various cancers, covering the full spectrum of therapeutic approaches to inhibiting STATs, and presenting emerging data from clinical trials.

Alister C. Ward is Foundation Professor/Director of Pre-Clinical Studies, School of Medicine, Deakin University, Geelong, Australia.

STATs in Health and Disease.- STAT Proteins in Cancer.- Translating STAT Inhibitors from the Lab to the Clinic.- Historical Development of STAT3 Inhibitors and Early Results in Clinical Trials.- STAT3 Inhibitors in Cancer: A Comprehensive Update.- Targeting Upstream Janus Kinases.- Inhibitors of Upstream Inducers of STAT Activation

Erscheinungsdatum	05.03.2022
Reihe/Serie	Cancer Drug Discovery and Development
Zusatzinfo	VII, 195 p. 11 illus. in color.
Verlagsort	Cham
Sprache	englisch
Maße	155 x 235 mm
Gewicht	320 g
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie
Themenwelt	Medizin / Pharmazie ► Studium
Schlagworte	Alternate inhibitors • cancer etiology • Inhibitors • STAT • transcription factors
ISBN-10	3-319-82701-4 / 3319827014
ISBN-13	978-3-319-82701-8 / 9783319827018
Zustand	Neuware