Atlas of Interstitial Cells of Cajal in the Gastrointestinal Tract

Terumasa Komuro (Autor)

Buch | Softcover

134 Seiten

2016 | Softcover reprint of the original 1st ed. 2012
Springer (Verlag)
978-94-017-7936-4 (ISBN)

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This atlas will illustrate the distribution and morphological features of interstitial cells of Cajal (ICC) which are the key cells to understanding of the regulatory mechanism of gastrointestinal motility, since ICC act as both pacemaker and as intermediates in neural transmission, and since ICC show specific distribution patterns depending on their anatomical positions. All subtypes of ICC located in the different tissue layers and different levels of the gastrointestinal tract will be revealed by immunohistochemistry for Kit receptors and nerves by using mainly whole-mount stretch preparation of the guinea-pig tissues. Three-dimensional reconstruction of confocal images will particularly help the readers to understand the peculiar arrangement of ICC networks in situ and the correlation between ICC and nerves. Electron micrographs will help illustrate the characteristic features of ICC and their ultrastructural differences from fibroblasts, smooth muscles and other interstitial cells.

1 Introduction; 2 Stomach; 3 Small intestine; 4 Duodenum; 5 Colon; 6 Caecum; 7 Ileocaecal Junction; 8 ICC found in the submucosal layer; 9 Ultrastructural demonstration of ICC; 10 Signal-pathways between the nerves and muscles not by means of ICC; 11 Issues for future studies

Erscheinungsdatum	18.08.2022
Zusatzinfo	XII, 134 p.
Verlagsort	Dordrecht
Sprache	englisch
Maße	178 x 254 mm
Themenwelt	Medizin / Pharmazie ► Studium
Schlagworte	c-kit • GI Tract • ICC • Morphology • Smooth musculature
ISBN-10	94-017-7936-8 / 9401779368
ISBN-13	978-94-017-7936-4 / 9789401779364
Zustand	Neuware