Advances in Cancer Biomarkers

From biochemistry to clinic for a critical revision

Buch | Softcover

372 Seiten

2016 | Softcover reprint of the original 1st ed. 2015
Springer (Verlag)
978-94-024-0420-3 (ISBN)

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At present there are a growing number of biomolecules under investigation to understand their potential role as cancer biomarker for diagnostic, prognostic and therapeutic purposes. Intriguingly, the state of art on cancer biomarkers research shows interesting and promising results together to clamorous failures. Also from a clinical point of view, there are contradictory results on routine clinical use of the present cancer biomarkers. Some patients may be simply monitored in their course by a periodic blood sample, but sometimes this monitoring shows dramatic limits. A lot of patients show serious and extensive relapses without significant change in serum concentrations of biomarkers tested. Often the physician who should utilize these biomarker does not entirely know their limits and the total potential applications as well and sometimes this knowledge is influenced by economical and marketing strategies. This limited and “polluted” knowledge may have dramatic consequences for patient. The aim of this book is to diffuse all aspects of cancer biomarkers, from their biochemical peculiarities to all clinical implications by passing through their physiology and pathophysiology.

This critical approach towards old and new cancer biomarkers should foster a deepened and useful understanding of the diagnostic and prognostic index of these fundamental parameters of laboratory medicine and in the same time facilitating the research of new and more sensitive-specific signals of the cancer cell proliferation.

Prelims.- I Generality.- II Tumor markers-a critical revision.- Enzymes.- Hormones.- Oncofetal proteins.- Cytokeratins.- Carbohydrate markers.- Blood group antigens.- Genetic markers.- Various protein markers.- III Perspectives.- The role of Circulating tumor Cells as tumor markers.- Index.

Erscheinungsdatum	23.09.2017
Reihe/Serie	Advances in Experimental Medicine and Biology ; 867
Zusatzinfo	21 Illustrations, color; 6 Illustrations, black and white; IX, 372 p. 27 illus., 21 illus. in color.
Verlagsort	Dordrecht
Sprache	englisch
Maße	178 x 254 mm
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie
	Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie
	Medizin / Pharmazie ► Studium
Schlagworte	Biomarkers • cancer diagnosis • cancer pathophysiology • Cancer Therapy • Metastasis
ISBN-10	94-024-0420-1 / 9402404201
ISBN-13	978-94-024-0420-3 / 9789402404203
Zustand	Neuware