Dialysis Amyloid

Charles Van Ypersele, Tilman B. Drüeke (Herausgeber)

Buch | Hardcover

290 Seiten

1996
Oxford University Press (Verlag)
978-0-19-262494-9 (ISBN)

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Amyloidosis is a condition associated with renal dialysis, leading to progressive organ failure, and is of great concern to all clinical nephrologists. This book is aimed at practising nephrologists and will help them successfully to diagnose, relieve, and possibly prevent dialysis-related amyloidosis.

Dialysis amyloidosis is a syndrome observed in dialysis patients characterized initially by joint pain, followed later by joint destruction. It is at present one of the few compliations in these patients.

The factors involved in the genesis of this syndrome are not yet known with certainty and there is as yet no proven efficacious treatment otehr then renal transplantation. As a result, the interest in this topic among nephrologists remains very high.

Dialysis amyloid gives general information on the pathophysiology, and the clinical aspects of all types of amyloidosis. It then goes on to discuss recently discovered B2, type of dialysis amyloidosis, from clinical and pathological features to physiological and pathophysiological aspects of this serious complication which effects patients suffering from chronic renal failure.

This book will give nephrologists and rheumatologists a clear understanding of the dialysis amyloidosis syndrome as well as making a valuable contribution to identifying strategies for treatment and prevention.

Part I: General aspects of amyloidosios ; 1. Pathpophysiology of amyloidogenesis ; 2. Various clinical types of amyloidosis ; Part II: Clinical characteristics of *B2=microglobulin amyloidosis ; 3. Arthropathy and carpal tunnel syndrome of *B2-microglobulin amyloidosis ; 4. Radiology of dialysis amyloidosis ; 5. Ultrasonography of the joints ; 6. Whole-body scintigraphy ; Part III: Pathology of *B2-microglobulin deposits ; 7. Composition of *B2-microglobulin deposits ; 8. Description, localization, and progression of B2-microglobulin dialysis-related amyloid deposition ; Part IV: Physiopathology of *B2-microglobulin accumulation and deposition ; 9. Characteristics of *B2-microglobulin metabolism ; 10. Involvement of *B2- microglobulin modified with AGEs in dialysis-related amyloidosis ; 11. Factors modifying removal and production of *B2-microglobulin ; 12. Determinants of fibril precipitation and aggregation in amyloid deposits. ; Part IV: Review of the clinical evidence on the prophylactic and therapeutic approaches to *B2-microglobulin amyloidosis ; 13. Prevention and treatment of *B2-microglobulin amyloidosis

Erscheint lt. Verlag	7.3.1996
Reihe/Serie	Oxford Clinical Nephrology Series
Zusatzinfo	black and white photographs, line figures and tables
Verlagsort	Oxford
Sprache	englisch
Maße	173 x 247 mm
Gewicht	720 g
Themenwelt	Medizinische Fachgebiete ► Innere Medizin ► Nephrologie
	Medizin / Pharmazie ► Medizinische Fachgebiete ► Urologie
	Studium ► 2. Studienabschnitt (Klinik) ► Anamnese / Körperliche Untersuchung
	Studium ► 2. Studienabschnitt (Klinik) ► Humangenetik
ISBN-10	0-19-262494-6 / 0192624946
ISBN-13	978-0-19-262494-9 / 9780192624949
Zustand	Neuware