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Antimicrobial Prophylaxis in Urology with special reference to the new Quinolones

T. Gasser (Autor)

Buch | Softcover

VIII, 76 Seiten

1992 | 1. Softcover reprint of the original 1st ed. 1992
Steinkopff (Verlag)
978-3-7985-0942-9 (ISBN)

Lese- und Medienproben

Inhaltsverzeichnis (PDF)

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This monograph gives an excellent review of the issue of antimicrobial prophylaxis in urol ogy and the use of the new fluoroquinolones in urology. The development of the fluoro quinolones has had a profound effect in urology, specifically because of the unique phar macokinetics of the fluoroquinolones with their two or more pK values, making concen tration of these compounds possible in the prostate. Their wide spectra against infecting organisms causing infections in the urinary tract have also made them popular and almost ideal in the treatment of urinary tract infections. This thesis summarizes in an concise way and brings up to date practically all our know ledge concerning the use of fluoroquinolones in urology. The chapter on antimicrobial prophylaxis covers our present knowledge completely, especially concerning the use of these drugs in antimicrobial prophylaxis in transurethral surgery. September 1992 PaulO. Madsen Madison, Wisconsin, USA v Contents Preface. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . V I. Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 1. 1. Author's Publications Referred to in Text . . . . . . . . . . . . . . . . . . . . . . 1 1. 2. Historical Background . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 1. 3. Problems of Antimicrobial Prophylaxis in Urology . . . . . . . . . . . . . . . . 2 D. General Considerations . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 2. 1. Definitions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 2. 1. 1. Bacteriuria and urinary tract infections . . . . . . . . . . . . . . . . . . . . . . 3 2. 1. 2. Bacteremia and septicemia .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 2. 1. 3. Nosocomial infections . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4 2. 1. 4. Wound infections . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5 2. 2. Pathophysiology of Infection . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5 2. 3. Specifics of Antimicrobial Agents to be Used in Prophylaxis . . . . . . . . . . 6 2. 4. Role of Quinolones . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6 2. 4. 1. Antimicrobial activity . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6 2. 4. 2. Pharmacokinetic properties . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Professor Dr. med. Thomas Gasser, Direktor der Urologischen Universitätsklinik Basel-Liestal/Klinik Liestal.

I. Introduction.- 1.1. Author's Publications Referred to in Text.- 1.2. Historical Background.- 1.3. Problems of Antimicrobial Prophylaxis in Urology.- II. General Considerations.- 2.1. Definitions.- 2.2. Pathophysiology of Infection.- 2.3. Specifics of Antimicrobial Agents to be Used in Prophylaxis.- 2.4. Role of Quinolones.- 2.5. Cost-Benefit Analysis of Antimicrobial Prophylaxis.- III. In Vitro Studies.- 3.1. Minimal Inhibitory Concentrations (MIC).- 3.2. Influence of Various Factors on MIC.- IV. Animal Studies.- 4.1. Drug Penetration into Various Tissues.- 4.2. Timing, Dosing, and Duration Studies.- 4.3. Bladder Irrigation Studies.- V. Human Studies and Review of the Literature.- 5.1. Catheterization and Urethral Dilatation.- 5.2. Endourologic Procedures.- 5.3. Open Surgery.- 5.4. Various Urologic Procedures.- 5.5. Various High-Risk Conditions.- VI. Literature.- VII. Summary.- VIII. Acknowledgements.- IX. Reprints of Papers I - VII.

Erscheint lt. Verlag	6.11.1992
Reihe/Serie	Fortschritte der Urologie und Nephrologie
Zusatzinfo	VIII, 76 p.
Verlagsort	Heidelberg
Sprache	englisch
Maße	170 x 244 mm
Gewicht	180 g
Themenwelt	Medizinische Fachgebiete ► Innere Medizin ► Nephrologie
	Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie
	Medizin / Pharmazie ► Medizinische Fachgebiete ► Urologie
	Studium ► Querschnittsbereiche ► Infektiologie / Immunologie
	Studium ► Querschnittsbereiche ► Prävention / Gesundheitsförderung
Schlagworte	Antimicrobial • Antimicrobial prophylaxis • Bacteremia • Bacteria • Infection • Infections • Infectious • infectious disease • Infectious Diseases • nosocomial infection • pathophysiology • Physiology • Transplantation
ISBN-10	3-7985-0942-5 / 3798509425
ISBN-13	978-3-7985-0942-9 / 9783798509429
Zustand	Neuware