Arterial Disorders

Definition, Clinical Manifestations, Mechanisms and Therapeutic Approaches

Adel Berbari, Giuseppe Mancia (Herausgeber)

Buch | Softcover

IX, 431 Seiten

2016 | 1. Softcover reprint of the original 1st ed. 2015
Springer International Publishing (Verlag)
978-3-319-35348-7 (ISBN)

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As our knowledge about arterial disease is greatly expanding, the aim of this book is to explore all aspects of arterial pathology, including classification, clinical manifestations, pathogenesis, and therapeutic options. The discussion of pathophysiologic mechanisms of arterial disease is wide ranging, encompassing hemodynamic, metabolic, humoral, inflammatory, genetic and environmental factors. Particular emphasis is placed on recent concepts, such as: the role of age-associated arterial alterations in the initiation and progression of cardiovascular diseases in older persons, the importance of mineral metabolism-bone vascular interactions, the clinical and prognostic significance of the renal resistive index, retinal circulation, toxemia of pregnancy as an arterial disease, and the role of pulmonary/vascular interaction in pulmonary hypertension and cross-talk of macrocirculation and microcirculation in target organ involvement. Evaluation procedures are carefully explained, and the full range of currently available therapeutic options, including lifestyle modifications and pharmacologic approaches, are described and appraised.

PART I Introduction: Definition/Epidemiology of arterial disease.- PART II Normal structure and physiology of the arterial system.- PART III Classification of arterial pathology and clinical manifestations: Atherosclerosis.- Arteriosclerosis.- Disease of Precapillary resistance vessels.- PART IV Pathogenetic mechanisms in arterial disease: Hemodynamic and mechanical factors.- Metabolic factors.- Inflammatory markers.- Neurohormonal interactions.- Mineral-bone/ arterial interactions.- Endothelial function and impairment.- Miscellaneous: Pharmacologic/factors/environmental factors.- PART V Systemic arterial disorders: Arterial aging.- Diabetes mellitus.- Metabolic Syndrome/obesity.- Chronic kidney disease/Renovascular interactions.- Pulmonary Hypertension/Pulmonary vascular interactions.- Systemic vasculitides.- Genetic/ degenerative disorders.- Hypertension.- Toxemia of pregnancy.- Kidney transplants, both donors and recipients.- PART VI Evaluation procedures: Arterial function.- Renal resistive index.- Retinal microcirculation.- PART VII Therapeutic options: Lifestyle modifications.- Pharmacologic approaches.

"This book defines and examines the pathophysiological mechanisms of arterial disorders. ... Although intended primarily for general physicians, basic scientists, and physiologists who manage cardiovascular disorders, the book is also useful for internists and medical trainees. ... The book includes a comprehensive reference list, color pictures, diagrams, and tables." (Dustin Y. Yoon, Doody's Book Reviews, May, 2015)

Erscheinungsdatum	14.10.2016
Zusatzinfo	IX, 431 p. 61 illus., 41 illus. in color.
Verlagsort	Cham
Sprache	englisch
Maße	155 x 235 mm
Themenwelt	Medizinische Fachgebiete ► Innere Medizin ► Kardiologie / Angiologie
Themenwelt	Medizinische Fachgebiete ► Innere Medizin ► Nephrologie
Schlagworte	angiology • Arterial ageing • Biomedicine general • Calcium phosphorus and bone metabolism • Cardiology • Cardiovascular medicine • Macro-/microcirculation cross-talk • Medical Research • Medicine • Medicine: general issues • Nephrology • Renal medicine and nephrology • Renal resistive index • Toxemia of pregnancy
ISBN-10	3-319-35348-9 / 3319353489
ISBN-13	978-3-319-35348-7 / 9783319353487
Zustand	Neuware