Immunotherapy of Type 1 Diabetes
John Wiley & Sons Ltd (Verlag)
978-0-471-92302-2 (ISBN)
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Recent national, European and international diabetes meetings have seen controversial discussions on the potential benefit and also on ethical aspects of immune intervention in patients with Type 1 diabetes or in persons with a high risk of developing the disease. This volume has been prepared to accompany the 1st International Symposium on the Immunotherapy of Type 1 Diabetes and represents the first attempt to bring together researchers and clinicians working in this field. The degree of interest in this topic was demonstrated by the formation of the International Diabetes Immunotherapy Group (IDIG), the registry of which is included at the end of this book. The editors of this text shared the view that a comprehensive review of attempts to cure or to predict diabetes was necessary at this stage in response to the increasing interest that many diabetologists now have in this field. Their aim was to describe and critically evaluate all therapeutic approaches that are currently being explored.
This volume is intended to provide guidelines for those diabetologists in highly specialized centres who may consider embarking on immune intervention trials in newly diagnosed diabetic patients.
Immunointervention in Type 1 diabetes - hope for prevention, D.Andreani; rationale of immune intervention in type 1 diabetes, J. Nerup; immunotherapy in organ-specific autoimmune diseases - success or failure, L.Bonomo; a new look to the mechanism of action of steroid hormones on the immune system, A.Gulino et al; mechanisms of action of anti-T-cell monoclonal antibodies, H.Waldmann; immunomodulators - mechanisms of action and guidelines for treatment, P.Pozzilli et al; cyclosporin treatment in diabetes, J.F.Bach; a critical evaluation of immunosuppression trials in Type 1 diabetes, J.Dupre and C.R.Stiller; a critical evaluation of immunomodulation trials in recent-onset Type 1 diabetes, G.Pozza and A.Secchi; metabolic and immunological parameters for monitoring immunotherapy in Type 1 diabetes, G.D.Bompiani et al; intensive insulin therapy and sustained remission in Type 1 diabetes mellitus, P.Brunetti and G.B.Bolli; new lines of intervention in Type 1 diabetes, L.C.Harrison; prediction of Type 1 diabetes - the Bart's-Windsor family study, P.J.Bingley and E.A.M.Gale; prediction of Type 1 diabetes and attempts at prevention - the Joslin study, G.S.Eisenbarth; - the Gainesville study, N.K.Maclaren; prediction of Type 1 diabetes and attempts at prevention - the Dusseldorf/Karlsburg study, H.Kolb; prediction of Type 1 diabetes - the Rome family study, G. Ghirlanda et al; immunodeficiency in long-standing diabetes - evidence and approaches to prevention, N.Visalli et al. Appendix: registry of Published Immune Intervention Trials in Type 1 diabetes with complete addresses of authors.
| Erscheint lt. Verlag | 29.3.1989 |
|---|---|
| Zusatzinfo | line drawings, tables, index |
| Verlagsort | Chichester |
| Sprache | englisch |
| Maße | 36 x 55 mm |
| Gewicht | 550 g |
| Themenwelt | Medizinische Fachgebiete ► Innere Medizin ► Diabetologie |
| ISBN-10 | 0-471-92302-8 / 0471923028 |
| ISBN-13 | 978-0-471-92302-2 / 9780471923022 |
| Zustand | Neuware |
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