Textbook of Receptor Pharmacology, Second Edition

John C. Foreman, Torben Johansen (Herausgeber)

Buch | Hardcover

289 Seiten

2002 | 2nd New edition
Crc Press Inc (Verlag)
978-0-8493-1029-4 (ISBN)

Infos

Focusing on drug receptors, this book includes chapters on G proteins and on tyrosine kinases as signal transductors. It contains over a hundred diagrams and tables to aid illustration of concepts, and practice problems to facilitate comprehension.

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The bestselling first edition of Textbook of Receptor Pharmacology originated from a renowned course in receptor pharmacology taught at the University College of London for the past three decades. Its innovative format united four major approaches to the study of receptors: molecular biology, quantitative functional studies of agonists and antagonists, ligand binding, and signal transduction systems. The second edition builds on this foundation.

This edition streamlines the material and focuses on cell membrane receptors along with their immediate signal transducers. The section on the molecular structure of receptors reflects the advances in this area. This edition also includes two restructured new chapters, one on G-proteins and one on tyrosine kinases, as signal transductors. Several chapters also contain problems for students to solve as well as worked-out solutions.

The book contains over one hundred useful diagrams and tables to aid illustration of concepts and a helpful appendix explaining the simple mathematics used in the text. A time-saving resource and comprehensive textbook, Textbook of Receptor Pharmacology, Second Edition provides in-depth, up-to-date coverage of this still rapidly expanding research area that is both fundamental to the science of pharmacology and on the cutting edge of new drug development.

Inhalt

Drug-Receptor Interactions
Classical Approaches to the Study of Drug-Receptor Interactions, D. H. Jenkinson

Molecular Structure of Receptors
Molecular Structure and Function of 7TM G-Protein Coupled Receptors, T. W. Schwartz and B. Holst
The Structure of Ligand-Gated Ion Channels, J. Egebjerg
Molecular Structure of Receptor Tyrosine Kinases, S. Gammeltoft New!

Ligand Binding Studies of Receptors
Direct Measurement of Drug Binding to Receptors, D. G. Haylett

Transduction of the Receptor Signal
Receptors Linked to Ion Channels: Mechanisms of Activation and Block, A. J. Gibb
G Proteins, D. A. Brown New!
Signal Transduction through Protein Tyrosine Kinases, I. Kramer

Receptors as Pharmaceutical Targets
Receptors as Pharmaceutical Targets, J. W. Black

Index

Produkt-Details

• Erscheint lt. Verlag: 28.8.2002
• Zusatzinfo: 68 Halftones, black and white; 21 Tables, black and white; 128 Illustrations, black and white
• Verlagsort: Bosa Roca
• Sprache: englisch
• Maße: 178 x 254 mm
• Gewicht: 703 g
• Themenwelt: Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie
• ISBN-10: 0-8493-1029-6 / 0849310296
• ISBN-13: 978-0-8493-1029-4 / 9780849310294
• Zustand: Neuware