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Antiphospholipid Antibody Syndrome

From Bench to Bedside

Pier Luigi Meroni (Herausgeber)

Buch | Hardcover

X, 267 Seiten

2014 | 2015
Springer International Publishing (Verlag)
978-3-319-11043-1 (ISBN)

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This book, part of the series Rare Diseases of the Immune System, offers comprehensive, up-to-date coverage of the pathophysiology and management of the antiphospholipid syndrome (APS). Immunologic and genetic aspects are discussed and the pathogenic mechanisms responsible for such phenomena as APS-mediated thrombosis and pregnancy loss/complications are explained. The main clinical manifestations, classification criteria and diagnostic tools are identified, and close attention is paid to the nature of the involvement of various organs or organ systems in APS. Specific chapters describe the treatment of the different symptoms, therapies of value in avoiding recurrences, and innovative treatment approaches. The authors are senior experts in the field who are aided by younger fellows, ensuring that the book is also educationally oriented. This handy volume will be a valuable tool for postgraduates in training and professionals wishing to extend their knowledge of this specific syndrome.

Foreword.- Preface.- 1 APS: Introductory notes.- 2 Immunology and Genetics of APS.- 3 The paradox of the lupus anticoagulant.- 4 The pathogenic mechanism(s) for APS-mediated thrombosis.- 5 The pathogenic mechanism(s) for APS-mediated pregnancy loss.- 6 Classification criteria.- 7 Non-classification criteria.- 8 Obstetric APS.- 9 APS and the nervous system.- 10 APS and renal involvement.- 11 Non-thrombotic hematologic manifestations in APS.- 12 Heart and APS.- 13 Skin and APS.- 14 Additional organs involved in APS (eye, ENT, GI, endocrine).- 15 Treatment of thrombosis.- 16 Treatment of pregnancy complications.- 17 Asymptomatic carries of APS.- 18 New treatments.- 19 Secondary APS.- 20 Catastrophic APS.

From the book reviews:

"The purpose is to provide an overview of this very difficult subject that will benefit bench researchers as well as bedside clinicians. The book would serve any audience who wants to know more about antiphospholipid syndrome. ... This is an excellent, up-to-date overview of antiphospholipid syndrome. It will serve as a handy tool to get more information on the topic." (Dany V. Thekkemuriyil, Doody's Book Reviews, February, 2015)

Erscheint lt. Verlag	3.12.2014
Reihe/Serie	Rare Diseases of the Immune System
Zusatzinfo	X, 267 p. 19 illus., 15 illus. in color.
Verlagsort	Cham
Sprache	englisch
Maße	155 x 235 mm
Gewicht	584 g
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Gynäkologie / Geburtshilfe
	Medizinische Fachgebiete ► Innere Medizin ► Hämatologie
	Medizinische Fachgebiete ► Innere Medizin ► Rheumatologie
Schlagworte	Antiphospholipid antibody syndrome • autoantibodies • Hughes Syndrome • Phospholipid binding proteins • Pregnancy complications • thrombosis
ISBN-10	3-319-11043-8 / 3319110438
ISBN-13	978-3-319-11043-1 / 9783319110431
Zustand	Neuware