Molecular Testing in Cancer (eBook)

George M. Yousef, Serge Jothy (Herausgeber)

eBook Download: PDF

2014 | 2014
XI, 442 Seiten
Springer New York (Verlag)
978-1-4899-8050-2 (ISBN)

Infos

Molecular Testing in Cancer provides a state of the art review of clinically relevant molecular pathology in cancer. The book provides a brief, easy to read review of commonly employed diagnostic molecular techniques including recently developed 'next generation' analytic tools, and offers a system-based run-through of the utility of molecular testing in individual cancer types, as well as reviewing current markers in cancer diagnosis, prognosis, and management. The volume also provides a prospective for the future which includes recently characterized and emerging biomarkers.

Written by experts in the field, Molecular Testing in Cancer serves as a useful and comprehensive resource for pathologists, hematologists, laboratory technicians and molecular scientists.

George M. Yousef, MD, PhD
University of Toronto, Department of Laboratory Medicine and Pathobiology, Toronto, ON, Canada

Serge Jothy, MD, PhD
University of Toronto, Department of Laboratory Medicine and Pathobiology, Toronto, ON, Canada

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Molecular Testing in Cancer provides a state of the art review of clinically relevant molecular pathology in cancer. The book provides a brief, easy to read review of commonly employed diagnostic molecular techniques including recently developed "e;next generation"e; analytic tools, and offers a system-based run-through of the utility of molecular testing in individual cancer types, as well as reviewing current markers in cancer diagnosis, prognosis, and management. The volume also provides a prospective for the future which includes recently characterized and emerging biomarkers.Written by experts in the field, Molecular Testing in Cancer serves as a useful and comprehensive resource for pathologists, hematologists, laboratory technicians and molecular scientists.

Inhalt

Part 1: Molecular approaches and techniques Chapter 1: Transitioning Diagnostic Molecular Pathology to the Genomic Era: Cancer Somatic Mutation Panel TestingKitchener D. Wilson and Iris Schrijver Chapter 2: Conventional and Molecular Cytogenetics in CancerMichelle Dolan Chapter 3: Comparative Genomic Hybridization and Array based CGH in CancerRoland Hubaux, Victor D. Martinez, David Rowbotham, and Wan L. Lam Chapter 4: Polymerase Chain ReactionMaria Pasic, Carlo Hojilia, and George M. Yousef Chapter 5: Single Nucleotide Polymorphisms (SNPs)Jyotsna Batra, Srilakshmi Srinivasan, and Judith Clements Chapter 6: Clinical Application of DNA Sequencing: Sanger and Next-Generation PlatformsJohn D. McPherson Chapter 7: Microarray-based Investigations in CancerMaud H.W. Starmans, Syed Haider, Cindy Yao, Philippe Lambin, and Paul C. Boutros Chapter 8: Proteomics in Cancer DiagnosticsKevin P. Conlon, Delphine Rolland, Kojo S. J. Elenitoba-Johnson Chapter 9: Circulating Tumor Cells: A Non-Invasive Liquid Biopsy in CancerEvi S. Lianidou Part 2: Molecular applications in various malignancies Chapter 10: Molecular Testing in Hematological MalignanciesAmir Behdad, Bryan L. Betz, Megan S. Lim, and Nathanael G. Bailey Chapter 11: Molecular Testing in Breast CancerDimitrios Zardavas, Debora Fumagalli, and Christos Sotiriou Chapter 12: Molecular Pathology of Gastrointestinal TumorsAndrea Grin and Serge Jothy Chapter 13: Molecular Testing in Pulmonary TumorsJeffrey J. Tanguay, Shirin Karimi, David M. Hwang, and Ming-Sound Tsao Chapter 14: Molecular testing in Gynecological MalignanciesPamela M. Ward and Louis Dubeau Chapter 15: Molecular Testing in Central Nervous System tumorsJason Karamchandani Chapter 16: Molecular Testing in Adult Kidney Tumors Manal Y. Gabril and George M. Yousef Chapter 17: Molecular Testing in Prostate CancerManal Y Gabril and George M Yousef Chapter 18: Molecular Testing in Urothelial TumorsManal Y Gabril and George M Yousef Chapter 19: Molecular Testing in Thyroid CancerMatthew T. Olson, Jason D. Prescott, and Martha A. Zeiger CHapter 20: Molecular Testing of Head and Neck TumorsDiana Bell and Ehab Y. Hanna Chapter 21: Molecular Testing in Bone and Soft Tissue TumorsBrendan C. Dickson, Gino R. Somers, Rita A. Kandel Chapter 22: Molecular testing in Cutaneous Melanoma   Margaret Redpath, Leon van Kempen, Caroline Robert, and Alan Spatz Chapter 23: Molecular Testing in Pediatric TumorsGino R. Somers and Paul S. Thorner Chapter 24: Pharmacogenomics in Molecular OncologyGregory J. Tsongalis Chapter 25: Quality Assurance in Molecular Testing of CancerSylviane Olschwang, Simon Patton, Etienne Rouleau, and Elisabeth Dequeker

Produkt-Details

• Erscheint lt. Verlag: 21.4.2014
• Zusatzinfo: XI, 442 p. 87 illus., 84 illus. in color.
• Verlagsort: New York
• Sprache: englisch
• Themenwelt: Medizinische Fachgebiete ► Innere Medizin ► Hämatologie
• Themenwelt: Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie
• Themenwelt: Studium ► 1. Studienabschnitt (Vorklinik) ► Biochemie / Molekularbiologie
• Themenwelt: Studium ► 2. Studienabschnitt (Klinik) ► Pathologie
• Schlagworte: epigenetics • methylation analysis • PCR • Proteomics • tumor markers
• ISBN-10: 1-4899-8050-4 / 1489980504
• ISBN-13: 978-1-4899-8050-2 / 9781489980502