Bacterial Resistance to Antimicrobials
Marcel Dekker Inc (Verlag)
978-0-8247-0635-7 (ISBN)
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Focuses on combating bacterial pathogens by understanding their strategies of defense!
Each chapter begins with a summary of concepts, so those not actively working in the field gain an overall picture of what follows!
Highlights antibiotic resistance in pathogens that poses the greatest threat to human health!
Containing nearly 2000 references for additional research, Bacterial Resistance to Antimicrobials
discusses the ecology of drug resistance genes, acquired response, and selection in natural bacterial populations
describes global response systems that are a basis of resistance
details antibiotic modification, inactivation, and host target modification as means of resistance development
considers efflux mechanisms, one of the major causes of multidrug resistance
covers concepts for developing therapies against multidrug resistant organisms
emphasizes the structural basis of lactamases and other enzymes involved in inactivation of antibiotics
surveys the epidemiology of methicillin resistance among nosocomial isolates and community-acquired strains
outlines molecular detection methods for mainstream diagnostic tests
assesses the promise of modern genomics to identify novel targets for drug discovery screening
Presenting the molecular basis, methods of detection and identification, and concepts for reducing the development and spread of resistant bacterial strains, Bacterial Resistance to Antimicrobials is an excellent reference for microbiologists, pharmacists, public health officials, infectious disease specialists, organic and medicinal chemists, and upper-level undergraduate and graduate students in these disciplines.
The Ecology of Antibiotic Resistance Genes
Abigail A. Salyers, Nadja B. Shoemaker, and George T. Bonheyo
Antibiotic Resistance: How Bacterial Populations Respond to a Simple Evolutionary Force
Fernando de la Cruz, Juan M. García-Lobo, and Julian Davies
Global Response Systems That Cause Resistance
Paul F. Miller and Philip Rather
Drug Efflux
Kim Lewis and Olga Lomovskaya
Mechanisms of Aminoglycoside Antibiotic Resistance
Gerard D. Wright
b-Lactamases and Resistance to b-Lactam Antibiotics
Lakshmi P. Kotra, Jean-Pierre Samama, and Shahriar Mobashery
Target Modification as a Mechanism of Antimicrobial Resistance
David C. Hooper
Antibiotic Permeability
Harry W. Taber
Phenotypic Tolerance of Bacteria
Rodger Novak and Elaine I. Tuomanen
Resistance as a Worldwide Problem
Rosamund Williams
Genetic Methods for Detecting Bacterial Resistance Genes
Amalio Telenti and Fred C. Tenover
Evolution and Epidemiology of Antibiotic-Resistant Pneumococci
Christopher Gerard Dowson and Krzysztof Trzcinski
Resistance Problems Associated with the Enterococcus
George M. Eliopoulos
Methicillin Resistance in Staphylococcus aureus Keeta S. Gilmore, Daniel F. Sahm, and Michael S. Gilmore
Drug Resistance and Tuberculosis Chemotherapy-From Concept to Genomics
Alexander S. Pym and Stewart T. Cole
Antibiotic Resistance in Enterobacteria
Nafsika H. Georgopapadakou
Public Health Responses to Antimicrobial Resistance in Outpatient and Inpatient Settings
Richard E. Besser, Julia Y. Morita, and Scott K. Fridkin
Approaches to New Antimicrobial Targets in the Age of Genomics
Philip J. Youngman
Index
| Erscheint lt. Verlag | 21.11.2001 |
|---|---|
| Verlagsort | New York |
| Sprache | englisch |
| Maße | 152 x 229 mm |
| Gewicht | 748 g |
| Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Mikrobiologie / Infektologie / Reisemedizin |
| Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie | |
| ISBN-10 | 0-8247-0635-8 / 0824706358 |
| ISBN-13 | 978-0-8247-0635-7 / 9780824706357 |
| Zustand | Neuware |
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