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Antimicrobial Resistance in the Environment (eBook)

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2011 | 1. Auflage
624 Seiten
John Wiley & Sons (Verlag)
978-1-118-15621-6 (ISBN)

Lese- und Medienproben

Antimicrobial Resistance in the Environment - Patricia L. Keen, Mark H. M. M. Montforts
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Examines effects of the environmental distribution of
antimicrobial resistance genes on human health and the
ecosystem

Resistance genes are everywhere in nature--in pathogens,
commensals, and environmental microorganisms. This contributed work
shows how the environment plays a pivotal role in the development
of antimicrobial resistance traits in bacteria and the distribution
of resistant microbial species, resistant genetic material, and
antibiotic compounds. Readers will discover the impact of the
distribution in the environment of antimicrobial resistance genes
and antibiotics on both the ecosystem and human and animal
health.

Antimicrobial Resistance in the Environment is divided into four
parts:

* Part I, Sources, including ecological and clinical consequences
of antibiotic resistance by environmental microbes

* Part II, Fate, including strategies to assess and minimize the
biological risk of antibiotic resistance in the environment

* Part III, Antimicrobial Substances and Resistance, including
antibiotics in the aquatic environment

* Part IV, Effects and Risks, including the effect of
antimicrobials used for non-human purposes on human health

Recognizing the intricate links among overlapping complex
systems, this book examines antimicrobial resistance using a
comprehensive ecosystem approach. Moreover, the book's
multidisciplinary framework applies principles of microbiology,
environmental toxicology, and chemistry to assess the human and
ecological risks associated with exposure to antibiotics or
antibiotic resistance genes that are environmental
contaminants.

Each chapter has been written by one or more leading researchers
in such fields as microbiology, environmental science, ecology, and
toxicology. Comprehensive reference lists at the end of all
chapters serve as a gateway to the primary research in the
field.

Presenting and analyzing the latest findings in a field of
growing importance to human and environmental health, this text
offers readers new insights into the role of the environment in
antimicrobial resistance development, the dissemination of
antimicrobial resistant genetic elements, and the transport of
antibiotic resistance genes and antibiotics.

Patricia Lynn Keen, Ph.D. received her doctorate in Resource Management Environmental Studies from the University of British Columbia. Mark H.M.M. Montforts, Ph.D. is a Senior Policy Officer and Project Leader with The National Institute for Public Health and the Environment in The Netherlands. He is also a member of many other organizations such as the Dutch Biocides Expertise Network, the Working Group on Ecotoxicology of the EU Committee for Human Medicinal Products (CHMP) at the European Medicines Agency (EMEA), and the Scientific Advisory Board of the National Asthma Foundation.

"This is an excellent publication, including primary data
and detailed explanations of specific studies and techniques as
well as review chapters. As both an introduction to a research area
and a call for greater study and thought into how we regulate
antimicrobial use in all spheres of society to limit further
resistance, I highly recommend Antimicrobial resistance in the
environment." (Phenotype, 1 February
2013)

"This book will be an ideal read for anyone seeking a
comprehensive introduction to the many reservoirs and routes a
resistance gene may pass through before or after its appearance in
a clinical setting. Even experts in the field stand to gain
knowledge regarding the complex web that is the issue of antibiotic
resistance in the environment." (The Quarterly
Review of Biology, 1 December 2012)

Erscheint lt. Verlag 30.11.2011
Sprache englisch
Themenwelt Medizin / Pharmazie Gesundheitsfachberufe
Studium 2. Studienabschnitt (Klinik) Pharmakologie / Toxikologie
Naturwissenschaften Biologie Biochemie
Naturwissenschaften Biologie Mikrobiologie / Immunologie
Naturwissenschaften Biologie Ökologie / Naturschutz
Technik
Schlagworte Ökologie • Ökologie / Mikroben • Biowissenschaften • Infectious Disease & Microbiology • Infektionskrankheiten u. Mikrobiologie • Life Sciences • Medical Science • Medizin • microbial ecology • Microbiology & Virology • Mikrobiologie • Mikrobiologie u. Virologie • Ökologie • Ökologie / Mikroben
ISBN-10 1-118-15621-8 / 1118156218
ISBN-13 978-1-118-15621-6 / 9781118156216
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