Missing Data in Clinical Studies (eBook)

Geerts Molenberghs, Michael Kenward (Autoren)

eBook Download: PDF

2007 | 1. Auflage
526 Seiten
John Wiley & Sons (Verlag)
978-0-470-51043-8 (ISBN)

Infos

Missing Data in Clinical Studies provides a comprehensive
account of the problems arising when data from clinical and related
studies are incomplete, and presents the reader with approaches to
effectively address them. The text provides a critique of
conventional and simple methods before moving on to discuss more
advanced approaches. The authors focus on practical and modeling
concepts, providing an extensive set of case studies to illustrate
the problems described.

* Provides a practical guide to the analysis of clinical trials
and related studies with missing data.

* Examines the problems caused by missing data, enabling a
complete understanding of how to overcome them.

* Presents conventional, simple methods to tackle these problems,
before addressing more advanced approaches, including sensitivity
analysis, and the MAR missingness mechanism.

* Illustrated throughout with real-life case studies and worked
examples from clinical trials.

* Details the use and implementation of the necessary statistical
software, primarily SAS.

Missing Data in Clinical Studies has been developed
through a series of courses and lectures. Its practical approach
will appeal to applied statisticians and biomedical researchers, in
particular those in the biopharmaceutical industry, medical and
public health organisations. Graduate students of biostatistics
will also find much of benefit.

Autor

Geert Molenberghs and Michael Kenward are the authors of Missing Data in Clinical Studies, published by Wiley.

Rezensionen

?Overall, this is an excellent text on missing data that is
engaging for practitioners while being rigorous enoughfor use in
the graduate biostatistics courses.?(Biometrics , September
2009)" "Missing Data in Clinical Studies does an excellent
job of presenting essential ideas on modern concepts and techniques
relevant to missing data in clinical studies." (Journal of the
American Statistician, December 2008)

"?this book is reasonably well organized and covers all the
relevant theory and much of the practical applications of the
field." (Journal of the American Chemical Association,
August 6, 2008)

"Missing Data in Clinical Studies does an excellent job of
presenting essential ideas on modern concepts and techniques
relevant to missing data in clinical studies." (Journal of
the American Statistician, December 2008)

"Clear, generally accessible and well written, and the content
is rich. This text is a highly recommendable addition to the
shelves of practicing statisticians." (Journal of Applied
Statistics, August 2008)

"The authors give key examples in the form of several clinical
trials and their analyses using the appropriate remedial
techniques." (Journal of Tropical Pediatrics, August
2007)

Produkt-Details

• Erscheint lt. Verlag: 4.4.2007
• Reihe/Serie: Statistics in Practice
• Reihe/Serie: Statistics in Practice
• Sprache: englisch
• Themenwelt: Mathematik / Informatik ► Mathematik ► Statistik
• Themenwelt: Mathematik / Informatik ► Mathematik ► Wahrscheinlichkeit / Kombinatorik
• Themenwelt: Medizin / Pharmazie ► Allgemeines / Lexika
• Themenwelt: Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie
• Schlagworte: Biostatistics • Biostatistik • Clinical Trials • Klinische Studien • Statistics • Statistik
• ISBN-10: 0-470-51043-9 / 0470510439
• ISBN-13: 978-0-470-51043-8 / 9780470510438